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个人简介

杨维涛,博士,现为同济大学医学院/生物医学工程与纳米科学研究院副教授,近年来围绕分子影像探针在恶性肿瘤早期诊断中的国家重大需求,聚焦分子探针研究领域的关键科学问题,开展了一系列基础应用研究,提出“蛋白仿生合成”策略,提高磁共振探针的特异性、敏感性和医用性,加快促进了磁共振探针的临床转化。目前,已主持国家自然科学基金面上项目、青年项目、上海市自然科学基金面上项目、上海市卫健委临床研究专项、同济大学自主原创基础研究项目、中国博士后面上项目、聚合物工程国家重点实验室开放课题等项目资助。近年来,以第一/共同第一作者在 ACS Nano(4篇),Biomaterials(2篇),Chemical Science,Theranostics, Small等国际期刊上共发表SCI论文20篇(其中IF>10的9篇,部分入选封面、封底和ESI前1%高被引),并获授权3项国家发明专利,获得同济大学医学院同医最美科技工作者称号。 教育经历 2012.09—2017.06 天津大学 材料学 工学博士 2016.12—2017.03 柏林自由大学 生物化学药学院 国家公派访问 2014.01—2016.10 同济大学 生物医学工程 联合培养 2008.09—2012.07 青岛科技大学 高分子科学与工程 工学学士 工作经历 2022.03-至今 同济大学 医学院 预聘副教授 2019.05-2022.02 同济大学 医学院 副研究员 2017.06-2019.05 同济大学 医学院 博士后(2019年同济大学优秀出站博后)

研究领域

磁共振分子影像探针的构建及其重大疾病诊疗应用

近期论文

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Weitao Yang#, Cuijun Deng#, Xiudong Shi#, Yan Xu, Chenyu Dai, Hui Wang, Kexin Bian, Tianming Cui, and Bingbo Zhang*. Structural and Molecular Fusion MRI Nanoprobe for Differential Diagnosis of Malignant Tumors and Follow-Up Chemodynamic Therapy. ACS Nano, 2023 (Online, IF: 18.0) . Weitao Yang, Xiudong Shi, Yuxin Shi, Defan Yao, Shizhen Chen, Xin Zhou, and Bingbo Zhang*, Beyond the Roles in Biomimetic Chemistry: An Insight into the Intrinsic Catalytic Activity of an Enzyme for Tumor-Selective Phototheranostics, ACS Nano, 2018, 12 (12): 12169-12180. (IF: 18.0) (Supplementary Cover) Weitao Yang#, Weisheng Guo#, Wenjun Le, Guoxian Lv, Fuhe Zhang, Lei Shi, Xiuli Wang, Jun Wang, Sheng Wang, Jin Chang*, and Bingbo Zhang*. Albumin-Bioinspired Gd:CuS Nanotheranostic Agent for In Vivo Photoacoustic/Magnetic Resonance Imaging-Guided Tumor-Targeted Photothermal Therapy, ACS Nano, 2016, 10(11): 10245-10257. ESI 1%高被引 (IF: 18.0,高被引论文) Weitao Yang#, Chenyang Xiang#, Yan Xu, Shizhen Chen, Weiwei Zeng, Kai Liu, Xiao Jin, Xin Zhou*, and Bingbo Zhang*, Albumin-constrained large-scale synthesis of renal clearable ferrous sulfide quantum dots for T1-Weighted MR imaging and phototheranostics of tumors. Biomaterials, 2020, 255, 120186.(IF: 15.3) Weitao Yang, Xiaoli Wu, Yan Dou, Jin Chang*, Chenyang Xiang, Jiani Yu, JunWang, Xiuli Wang, Bingbo Zhang*, A human endogenous protein exerts multi-role biomimetic chemistry in synthesis of paramagnetic gold nanostructures for tumor bimodal imaging, Biomaterials, 2018, 161: 256-269.(IF: 15.3) Weitao Yang, Weisheng Guo, Xiaoqun Gong, Bingbo Zhang*, Sheng Wang, Na Chen, Wentao Yang, Yu Tu, Xiangming Fang, and Jin Chang*, Facile Synthesis of Gd-Cu-In-S/ZnS Bimodal Quantum Dots with Optimized Properties for Tumor Targeted Fluorescence/MR in Vivo Imaging. ACS Applied Materials & Interfaces, 2015, 7(33): 18759-18768.(IF: 10.3) Weitao Yang, Bingbo Zhang*, Porphyrin-based nanocomposites for tumor photodynamic therapy. MRS Bulletin, 2019, 44(3), 189-194. Weitao Yang#, Weisheng Guo#, Jin Chang*, Bingbo Zhang*. Protein/peptide-templated biomimetic synthesis of inorganic nanoparticles for biomedical applications. Journal of Materials Chemistry B, 2017. Weitao Yang, Weisheng Guo, Jin Chang*, Bingbo Zhang*, Synthesis of Noble Metal Nanoclusters Based on Protein and Peptide as a Template. Acta Chim. Sinica, 2014, 72(12): 1209-1217. Peiru Wang#, Weitao Yang#, Shuzhan Shen#, Chao Wu, Long Wen, Qian Cheng, Bingbo Zhang* and Xiuli Wang*,Differential Diagnosis and Precision Therapy of Two Typical Malignant Cutaneous Tumors Leveraging Their Tumor Microenvironment: A Photomedicine Strategy. ACS Nano, 2019, 13, 11168-11180. (并列第一) Yan Xu#, Weitao Yang#, Yi Han#, Kexin Bian, Weiwei Zeng, Liangwen Hao, Hui Wang, Yingsheng Cheng, Peijun Wang, and Bingbo Zhang*. Biomimetic Molybdenum Sulfide-Catalyzed Tumor Ferroptosis and Bioimaging. Small, 2023, 2207544. (并列第一) Liangwen Hao#, Weitao Yang#, Yan Xu#, Tianming Cui, Guoqi Zhu, Weiwei Zeng, KexinBian, Hongying Liang, Pengfei Zhang and Bingbo Zhang*. Engineering Light-Initiated Afterglow Lateral Flow Immunoassay for Infectious Disease Diagnostics. Biosensors and Bioelectronics, 2022, 212, 114411. (并列第一) Yan Xu#, Weitao Yang#, Defan Yao, Kexin Bian, Weiwei Zeng, Kai Liu, Dengbin Wang and Bingbo Zhang*, An aggregation-induced emission dye-powered afterglow luminogen for tumor imaging. Chemical Science, 2020, 11, 419-428. (并列第一) Xiudong Shi#, Weitao Yang#, Qiong Ma, Yang Lu, Yan Xu, Kexin Bian, Fengjun Liu, Chunzi Shi, Han Wang*, Yuxin Shi*, and Bingbo Zhang*,Hemoglobin-mediated biomimetic synthesis of paramagnetic O2-evolving theranostic nanoprobes for MR imaging-guided enhanced photodynamic therapy of tumor.Theranostics 2020, 10(25):11607-11621(并列第一). Xiao Jin#, Weitao Yang#, Yan Xu, Kexin Bian, Bingbo Zhang*, Emerging strategies of activatable MR imaging probes and their advantages for biomedical applications,View, 2021, 2(5): 20200141. (Front Cover, Invited,并列第一) Weisheng Guo#, Weitao Yang#, Bingbo Zhang*, Jin Chang*, and Xiaoyuan Chen*, Color-tunable Gd-Zn-Cu-In-S/ZnS quantum dots for dual modality magnetic resonance and fluorescence imaging, Nano Research, 2014, 7(11): 1581-1591. (并列第一) Jiani Yu#, Weitao Yang#, Shige Xing, Jun Wang, Huanxing Han, Pengfei Zhang, Chenyang Xiang, and Bingbo Zhang*, Blended gold/MnO2@BSA nanoparticles for fluorometric and magnetic resonance determination of ascorbic acid, Microchimica Acta, 2019, 186 (2), 89. (并列第一) Sheng Wang#, Weitao Yang#, Jin Chang*, Xiaoqun Gong* and Bingbo Zhang*, Multifunctional reduction-responsive SPIO&DOX-loaded PEGylated polymeric lipid vesicles for magnetic resonance imaging-guided drug delivery, Nanotechnology, 2016, 27(16): 165101. (并列第一).

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