郝爱军 - 山东大学 - 基础医学院

个人简介

毕业于山东医科大学获得医学学士及硕士学位，在新加坡国立大学获得医学博士学位，在新加坡细胞与分子生物学研究所任Research Fellow，现任组织胚胎学系主任。

研究领域

主要从事神经发育及相关疾病机制研究，构建了多种转基因小鼠及神经系统疾病相关模型，重点关注神经干细胞命运调控机制，神经系统发育及疾病中胶质细胞作用机制，以及发育相关精神疾病机制研究，靶向干细胞或胶质细胞，筛选关键蛋白及小分子药物，并结合NSC、MSC等干细胞及其衍生外泌体，开展神经系统疾病相关的治疗研究

近期论文

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Zhao T, Wu D, Du J, Liu G, Ji G, Wang Z, Peng F, Man L, Zhou W, Hao A*. Folic Acid Attenuates Glial Activation in Neonatal Mice and Improves Adult Mood Disorders Through Epigenetic Regulation.Front Pharmacol. 2022 Feb7; 13:818423. Zhao M, Yao Y, Du J, Kong L, Zhao T, Wu D, Man L, Zhou W*.6-Gingerol Alleviates Neonatal Hypoxic-Ischemic Cerebral and White Matter Injury and Contributes to Functional Recovery.Front Pharmacol. 2021 Sep 22; 12:707772. Ji G, Zhou J, Du J, Zhou J, Zhao M, Yang L, Hao A*. PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment.Cell Death Dis. 2021 Jun 19;12(7):633. Li X, Ji G, Zhou J, Du J, Li X, Shi W, Hu Y, Zhou W*, Hao A*. Pcgf1 Regulates Early Neural Tube Development Through Histone Methylation in Zebrafish.Front Cell Dev Biol. 2021 Jan 26; 8:581636. Wang X, Zhou W, Ren J, Ji G, Du J, Tian W, Liu Q, Hao A*. Graphene oxide suppresses the growth and malignancy of glioblastoma stem cell-like spheroids via epigenetic mechanisms.J Transl Med. 2020 May 14;18(1):200. Zhou W, Zhao T, Du J, Ji G, Li X, Ji S, Tian W, Wang X, Hao A*. TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation.Cell Death Dis.201927;10(3):198. Ji S, Zhou W, Li X, Liu S, Wang F, Li X, Zhao T, Ji G, Du J, Hao A*. Maternal hyperglycemia disturbs neocortical neurogenesis via epigenetic regulation in C57BL/6J mice.Cell Death Dis.2019 Mar 1;10(3):211. Li X, Zhou W, Li X, Gao M, Tian W, Ji S, Du J, Hao A*. SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish,Stem Cell Res Ther. 2019 Dec 16;10(1):389. Liu S, Guo Y,Yuan Q, Pan Y, Wang L, Liu Q, Wang F, Wang J*, Hao A*. Melatonin prevents neural tube defects in the offspring of diabetic pregnancy.J Pineal Res.2015 Nov;59(4):508-17.