当前位置: X-MOL首页全球导师 国内导师 › 刘晓雨

个人简介

工作经历 2022.03至今 教授 同济大学生命科学与技术学院 2019.02至今 研究员 同济大学附属东方医院再生医学研究所 2018.08-2022.02 特聘研究员 同济大学生命科学与技术学院/同济大学高等研究院 2017.11-2018.10 访问学者 康奈尔大学医学院,New York,NY,USA 2016.06-2018.07 博士后 同济大学生命科学与技术学院 学习经历 2011.07 – 2016.06 博士 生物化学与分子生物学 北京生命科学研究所(NIBS) 2007.09 – 2011.06 学士 生物技术,生命科学学院,南开大学

研究领域

1,哺乳动物植入前胚胎的表观遗传调控机制 2,细胞早期分化和命运决定的表观遗传机制研究 3,哺乳动物早期胚胎发育中关键转录因子对表观修饰和基因表达的调控机制研究 4,单细胞和微量细胞测序技术

发育生物学,表现遗传学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Ruimin Xu1, Sen Li1, Qiu Wu1, Chong Li1, Manxi Jiang1, Lei Guo, Mo Chen, Lingyue Yang, Xin Dong, Hong Wang, Chenfei Wang*, Xiaoyu Liu*, Xianghong Ou*, Shaorong Gao*. Stage-specific H3K9me3 allocations ensure retrotransposon silencing in human preimplantation embryos. Cell Stem Cell, 2022. Chenfei Wang1, Chuan Chen1, Xiaoyu Liu1, Chong Li1, Qiu Wu, Xiaolan Chen, Lingyue Yang, Xiaochen Kou, Yanhong Zhao, Hong Wang, Yawei Gao*, Yong Zhang*, Shaorong Gao*.Dynamic nucleosome organization after fertilization reveals regulatory factors for mouse zygotic genome activation. Cell Research, 2022 Lingyue Yang1, Xiaocui Xu1, Ruimin Xu, Chuan Chen, Xiaolei Zhang, Mo Chen, Xiaochen Kou, Yanhong Zhao, Hong Wang, Xiaoyu Liu*, Shaorong Gao*, Chong Li*.Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq. Stem Cell Reports, 2022 Xu Rumin1, Li Chong1, Liu Xiaoyu*, Gao Shaorong*. Insights into epigenetic patterns in mammalian early embryos. Protein & Cell. 2021 Xiaolei Zhang, Shaorong Gao*, Xiaoyu Liu*, Advance in the Role of Epigenetic Reprogramming in Somatic Cell Nuclear Transfer-Mediated Embryonic Development, Stem Cells International, vol. 2021, Chen, Mo1; Zhu, Qianshu1; Li, Chong1; Kou, Xiaochen; Zhao, Yanhong; Li, Yanhe; Xu, Ruimin; Yang, Lei; Yang, Lingyue; Gu, Liang; Wang, Hong; Liu, Xiaoyu*; Jiang, Cizhong*; Gao, Shaorong*; Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos, Nature Communications,2020. Tiegang Meng1, Qian Zhou1, Xueshan Ma1, Xiaoyu Liu1, Qingren Meng, Xianju Huang, Honglin Liu, Wenlong Lei , Zhenghui Zhao, Yingchun Ouyang, Yi Hou, Heide Schatten, Xianghong Ou*, Zhenbo Wang *, Shaorong Gao* & Qingyuan Sun *.PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome. Nature Communications, 2020 Chenfei Wang1, Xiaoyu Liu1, Yawei Gao*1, Lei Yang1, Chong Li, Wenqiang Liu, Chuan Chen, Xiaochen Kou, Yanhong Zhao, Jiayu Chen, Yixuan Wang, Rongrong Le, Hong Wang, Tao Duan, Yong Zhang*, Shaorong Gao*. Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development. Nature Cell Biology,2018,20(5):620-631 (co-first author) Yawei Gao1, Xiaoyu Liu1, Bin Tang1, Chong Li1, Zhaohui Kou, Lin Li, Wenqiang Liu, You Wu, Xiaochen Kou, Jingyi Li, Yanhong Zhao, Jiqing Yin, Hong Wang, She Chen, Lujian Liao*, Shaorong Gao*. Protein expression landscape of mouse embryos during pre-implantation development. Cell Reports, 2017, 21(13):3957-3969 (co-first author) Xiaoyu Liu1, Chenfei Wang1, Wenqiang Liu1, Jingyi Li1, Chong Li, Xiaochen Kou, Jiayu Chen, Yanhong Zhao, Haibo Gao, Hong Wang, Yong Zhang*, Yawei Gao*, Shaorong Gao*. Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos. Nature, 2016. 537: p.558-562. Wenqiang Liu1, Xiaoyu Liu1, Chenfei Wang1, Yawei Gao1*, Rui Gao, Xiaochen Kou, Yanhong Zhao, Jingyi Li, You Wu, Wenchao Xiu, Su Wang, Jiqing Yin, Wei Liu, Tao Cai, Hong Wang, Yong Zhang*, Shaorong Gao*. Identification of key factors releasing cloned embryo arrests by combining embyo biopsy and single-cell sequencing. Cell Discovery, (2016) 2, 16010; doi:10.1038/celldisc.2016.10. (co-first author)

推荐链接
down
wechat
bug