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李浩宇,哈工大仪器科学与工程学院,教授,博士生导师,国家优青,哈工大先进光电成像技术课题组长。研究方向包括:光学超分辨显微镜;计算成像技术;多模态光电仪器;全息光学等。近年来,以第一/通信(共)作者在学术期刊Nature Biotechnology, Nature Photonics, Nature Communications, Light: Science & Applications等发表论文50余篇。参加国内外学术会议并作邀请报告60余次,申请中国专利20项,国际专利10项。主持国家自然科学基金(青年、优青、仪器专项)和国家重点研发计划课题等。担任中国仪器仪表学会青年委员;中国仪器仪表学会显微分会委员;中国光学工程学会计算成像专业委员会委员;《激光与光电子学进展》杂志青年编委。成果入选2021年中国光学领域十大社会影响力事件;2022年中国光学十大进展(应用研究类提名奖)。主讲本科专业必修课《工程光学2》和创新研修课《新一代光学显微成像技术》。 教育经历 2011/09-2015/12,爱尔兰都柏林大学,电子工程,博士(导师:John T. Sheridan教授) 2009/09-2011/07,哈尔滨工业大学,电磁场与微波技术,硕士 2005/09-2009/07,哈尔滨工业大学,通信工程,本科 工作经历 2021年12月-至今,哈尔滨工业大学,仪器科学与工程学院,教授,博士生导师 2018年1月-2021年12月,哈尔滨工业大学,仪器科学与工程学院,副教授,博士生导师 2015年11月-2017年12月,美国纽约州立大学石溪分校,生物医学工程系,博士后 荣誉称号 2023年9月,全国高校黄大年式教师团队(谭久彬院士团队) 2023年4月,中国光学十大进展(应用研究类提名奖) 2023年1月,黑龙江省高层次人才B类 2022年12月,哈工大青年科学家工作室 2022年8月,国家自然科学基金优秀青年基金 2022年1月,中国光学领域十大社会影响力事件 2021年12月,哈工大科学原创探索奖 2021年7月,黑龙江省自然科学基金优秀青年基金 2019年11月,中国仪器仪表学会金国藩青年学子奖 2019年8月,黑龙江省头雁计划(谭久彬院士团队) 2018年10月,中国科协青年人才托举工程 2017年10月,哈工大青年拔尖人才选聘计划

研究领域

4D荧光光场显微镜,对全细胞空间动态活体状态下虚拟现实重现技术 深度学习荧光显微成像 三维成像光场微型化显微镜 超分辨显微成像技术 四维光场荧光显微成像系统 三维信息加密技术 光波导自激与调制 高密度全息存储

近期论文

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Weisong Zhao#, Xiaoshuai Huang#, Jianyu Yang#, Liying Qu, Guohua Qiu, Yue Zhao, Xinwei Wang, Deer Su, XUMIN Ding, Heng Mao, Yaming Jiu, Ying Hu, Jiubin Tan, Shiqun Zhao*, Leiting Pan*, Liangyi Chen*, and Haoyu Li*. Quantitatively mapping local quality of super-resolution microscopy by rolling Fourier ring correlation, Light: Science & Applications, 12, 298 (2023). (Nature期刊,光学类顶刊,2022年影响因子:20.3) 原文链接:https://doi.org/10.1038/s41377-023-01321-0 Deer Su, Weida Gao, Haoyu Li, Changliang Guo, and Weisong Zhao*, "Highly flexible and compact volumetric endoscope by integrating multiple micro-imaging devices," Optics Letters, 48(24), 6416 (2023).(JCR一区,影响因子:3.56) 原文链接:https://doi.org/10.1364/OL.506261 Yue Zhang, Xiaowei Zhang, Zhongyi Li, Weisong Zhao, Hui Yang, Shuangshuang Zhao, Daijiao Tang, Qian Zhang, Zonghong Li, Huisheng Liu, Haoyu Li, Bo Li, Pekka Lappalainen, Tao Xu, Zongqiang Cui, Yaming Jiu. Single particle tracking reveals SARS-CoV-2 regulating and utilizing dynamic filopodia for viral invasion, Science Bulletin (2023). (Q1区,影响因子:18.9) 原文链接:DOI: https://doi.org/10.1016/j.scib.2023.08.031 Weisong Zhao#, Shiqun Zhao#, Zhenqian Han#, Xiangyan Ding#, Guangwei Hu, Liying Qu, Yuanyuan Huang, Xinwei Wang, Heng Mao, Yaming Jiu, Ying Hu, Jiubin Tan, Xumin Ding*, Liangyi Chen*, Changliang Guo* & Haoyu Li*. Enhanced detection of fluorescence fluctuations for high-throughput super-resolution imaging, Nature Photonics, 17, 806–813 (2023). (2023年9月封面文章)(影响因子:39.7,顶刊) . 原文链接:DOI:10.1038/s41566-023-01234-9 Abstractly, the individually fluctuating molecules distributed in the strong background are like the “shining stars in the mist” to some extent. Our core intention is to dispel such “mist” before the cumulant calculation, to enable high-quality SR under real physiological conditions. Xinwei Wang, Hao Wang, Jinlu Wang, Xingsi Liu, Huijie Hao, You Sin Tan, Yilei Zhang, He Zhang, Xiangyan Ding, Weisong Zhao, Yuhang Wang, Zhengang Lu, Jian Liu, Joel K. W. Yang, Jiubin Tan, Haoyu Li*, Cheng-Wei Qiu*, Guangwei Hu* & Xumin Ding*. Single-shot isotropic differential interference contrast microscopy. Nature Communications, 14, 2063 (2023). (影响因子:14.919,顶刊) 原文链接:https://doi.org/10.1038/s41467-023-37606-6 Guanyu Shang, Guoyu Li, Chunsheng Guan, Weisong Zhao, Haoyu Li*, Kuang Zhang, Jian Liu, Qun Wu, Xue-Mei Ding, Shah Nawaz Burokur*, and Xumin Ding*. Metasurface with Directional-Controlled Asymmetric Transmissions. Advanced Photonics Research, 2200359, 2023. 原文链接:https://doi.org/10.1002/adpr.202200359 Guanyu Shang, Chunsheng Guan, Kuang Zhang, Qun Wu, Jian Liu, Xue-Mei Ding, Haoyu Li*, Shah Nawaz Burokur* and Xumin Ding*. Design of a frequency-multiplexed metasurface with asymmetric transmission. Optics Letters, 47(17), 4504-4507, 2022. (JCR一区,影响因子:3.56) 原文链接:https://doi.org/10.1364/OL.464854 Guanyu Shang, Guangwei Hu, Chunsheng Guan, Yue Wang, Kuang Zhang, Qun Wu, Jian Liu, Xue-Mei Ding, Shah Nawaz Burokur*, Haoyu Li*, Xumin Ding*, and Cheng-Wei Qiu*, A non-interleaved bidirectional Janus metasurface with full-space scattering channels. Nanophotonics, 2022. (光学顶刊,影响因子7.923) 原文链接:https://doi.org/10.1515/nanoph-2022-0292 Zihan Zhao#, Yue Wang#, Chunsheng Guan#, Kuang Zhang, Qun Wu, Haoyu Li*, Jian Liu, Shah Nawaz Burokur* and Xumin Ding*, Deep learning enabled compact optical trigonometric operator with metasurface. PhotoniX, 3(15), (2022). (光学顶刊,影响因子19.818,JCR1区) 原文链接:DOI: https://doi.org/10.1186/s43074-022-00062-4 Zhuochao Wang#, Guangwei Hu#, Xinwei Wang#, Xumin Ding*, Kuang zhang*, Haoyu Li*, Shah Nawaz Burokur*, Qun Wu, Jian Liu, Jiubin Tan, and Cheng-Wei Qiu*, Single-layer spatial analog meta-processor for imaging processing, Nature Communications, 13, 2188, (2022). (影响因子:14.919,顶刊) 原文链接:DOI: https://www.nature.com/articles/s41467-022-29732-4 Deer Su#, Xinwei Wang#, Guanyu Shang, Xumin Ding*, Shah Nawaz Burokur*, Jian Liu, and Haoyu Li*, Amplitude-phase modulation metasurface hologram with inverse angular spectrum diffraction theory, Journal of Physics D: Applied Physics 55, 235102 (2022). (SCI, 影响因子:3.207) 原文链接:DOI: https://doi.org/10.1088/1361-6463/ac5699 Zihan Zhao, Yue Wang, Xumin Ding*, Kuang Zhang, Haoyu Li*, Jia-Hui Fu, Shah Nawaz Burokur*, Qun Wu, Compact logic operator utilizing single-layer metasurface, Photonics Research, 10(2) (2022). (JCR一区,2020年影响因子7.08) 原文链接:DOI: https://doi.org/10.1364/PRJ.439036 Weisong Zhao#, Shiqun Zhao#, Liuju Li#, Xiaoshuai Huang, Shijia Xing, Yulin Zhang, Guohua Qiu, Zhenqian Han, Yingxu Shang, De-en Sun, Chunyan Shan, Runlong Wu, Lusheng Gu, Shuwen Zhang, Riwang Chen, Jian Xiao, Yanquan Mo, Jianyong Wang, Wei Ji, Xing Chen, Baoquan Ding, Yanmei Liu, Heng Mao, Baoliang Song, Jiubin Tan, Jian Liu, Haoyu Li*, Liangyi Chen*.Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy, Nature Biotechnology, 40, 606-617, (2022). (影响因子: 68.164,顶刊) . 原文链接:https://doi.org/10.1038/s41587-021-01092-2 Our sparse deconvolution confers a general computational method to improve the ability of fluorescence microscopes to resolve structures beyond those permitted by their hardware optics, thus shall be of high potential impact for the life sciences researchers Haoyu Li, Liying Qu, Zijie Hua, Xinwei Wang, Weisong Zhao, Jian Liu. Deep Learning Based Fluorescence Microscopy Imaging Technologies and Applications[J]. Laser & Optoelectronics Progress, 2021, 58(18): 1811007 (in chinese) 李浩宇, 曲丽颖, 华子杰, 王新伟, 赵唯淞, 刘俭. 基于深度学习的荧光显微成像技术及应用[J]. 激光与光电子学进展, 58(18) 2021. (特邀综述) Guanyu Shang, Haoyu Li, Zhuochao Wang, Shah Nawaz Burokur,* Kuang Zhang,* Jian Liu, Qun Wu, Xuemei Ding, and Xumin Ding*, Transmission-Reflection-Integrated Multiplexed Janus Metasurface, ACS Applied Electronic Materials 2021. DOI: https://doi.org/10.1021/acsaelm.1c00246 Guanyu Shang, Zhuochao Wang, Haoyu Li, Kuang Zhang , Qun Wu , Shah Nawaz Burokur, and Xumin Ding*, Metasurface Holography in the Microwave Regime, Photonics, 8(5), 135 (2021). (SCI,影响因子:2.14) DOI: https://doi.org/10.3390/photonics8050135 Guanyu Shang, Haoyu Li, Zhuochao Wang, Kuang Zhang, Shah Nawaz Burokur, Jian Liu, Qun Wu, Xuemei Ding, and Xumin Ding*, Coding metasurface holography with polarization-multiplexed functionality, Journal of Applied Physics 129, 035304 (2021). (SCI, 影响因子:2.286) DOI: https://doi.org/10.1063/5.0036027 K Zhang*, Y Yuan, X Ding*, Haoyu Li, B Ratni, Q Wu, J Liu, SN Burokur*, J Tan, Polarization-Engineered Noninterleaved Metasurface for Integer and Fractional Orbital Angular Momentum Multiplexing, Laser & Photonics Reviews 15 (1), 2000351, (2021). (SCI, 影响因子:10.655, 中科院一区) DOI: https://doi.org/10.1002/lpor.202000351 Yue Wang#, Chunsheng Guan#, Haoyu Li#, Xumin Ding*, Kuang Zhang*, Jinxiang Wang, Shah Nawaz Burokur*, Jian Liu, Qun Wu, Dual-polarized Tri-channel Encrypted Holography Based on Geometric Phase Metasurface, Advanced Photonics Research, 1, 2000022, (2020). DOI: https://doi.org/10.1002/adpr.202000022 Chunsheng Guan#, Haoyu Li#, Xumin Ding*, Zhuochao Wang, Kuang Zhang*, Ming Jin, Shah Nawaz Burokur*, Jian Liu, and Qun Wu, Dual-Polarized Dual-Channel Helicity-Switching or Helicity-Preserving Retroreflectors Utilizing 1-Bit Coding Metasurfaces, ACS Applied Electronic Materials,2, 10, 3380-3389, (2020). DOI: https://doi.org/10.1021/acsaelm.0c00650 Zhuochao Wang#; Jian Liu#; Xumin Ding*; Weisong Zhao; Kuang Zhang*; Haoyu Li*; Badreddine Ratni; Shah Nawaz Burokur*; Qun Wu, Three-Dimensional Microwave Holography Based on Broadband Huygens' Metasurface. Physical Review Applied, 13 (1), 014033 (2020). (SCI, 影响因子:4.194, 中科院一区) DOI: https://doi.org/10.1103/PhysRevApplied.13.014033 Chunsheng Guan#, Jian Liu#, Xumin Ding*, Zhuochao Wang, Kuang Zhang*, Haoyu Li, Ming Jin,Shah Nawaz Burokur* and Qun Wu, Dual-polarized multiplexed meta-holograms utilizing coding metasurface, Nanophotonics, 20200237 (2020). (SCI, 影响因子:7.491, 中科院一区,光学顶刊) DOI: https://doi.org/10.1515/nanoph-2020-0237 Xumin Ding#, Zhuochao Wang#, Guangwei Hu#, Jian Liu#, Kuang Zhang, Haoyu Li, Badreddine Ratni, Shah Nawaz Burokur, Qun Wu, Jiubin Tan & Cheng-Wei Qiu*, Metasurface Holographic Image Projection based on Mathematical Properties of Fourier Transform. PhotoniX 1, 16 (2020).(光学顶刊,影响因子19.818,JCR1区) DOI: https://doi.org/10.1186/s43074-020-00016-8 Jian Liu, Yixuan Zhao, Cheng Guo, Weisong Zhao, Yutian Zhang, Changliang Guo, and Haoyu Li,*. Robust autofocusing method for multi-wavelength lensless imaging. Optics Express, 27(17), 23814-23829, (2019). (SCI, IF=3.669, 中科院二区) DOI: https://doi.org/10.1364/OE.27.023814 Changliang Guo,Wenhao Liu, Xuanwen Hua, Haoyu Li, and Shu Jia*. Fourier Light-Field Microscopy. Optics Express, 27(18) 25573-25594, (2019). (SCI, IF=3.669, 中科院二区) DOI: https://doi.org/10.1364/OE.27.025573 Haoyu Li, Changliang Guo, Deborah Kim-Jolzapfel, Weiyi Li,Yelena Altshuller, Bryce Schroeder, Wenhao Liu, Yizhi Meng, Jarrod B. French, Ken-Ichi Takamaru, Micheal A. Frohman, and Shu Jia. Fast, volumetric live-cell imaging using high-resolution light-field microscopy, Biomedical Optics Express, 10, 29–49,(2019). (SCI, IF=3.921, 中科院二区) DOI: https://doi.org/10.1364/BOE.10.000029 Ra'ed Malallah, Haoyu Li, Yue Qi, Derek Cassidy, Inbarasan Muniraj, Nebras Al-Attar, and John T. Sheridan. Improving the uniformity of holographic recording using multi-layer photopolymer: Part I. Theoretical analysis, Journal of the Optical Society of America A, 36, 320–333, (2019). (SCI, IF=1.791) DOI: https://doi.org/10.1364/JOSAA.36.000320 Ra'ed Malallah, Haoyu Li, Yue Qi, Derek Cassidy, Inbarasan Muniraj, Nebras Al-Attar, and John T. Sheridan. Improving the uniformity of Holographic Recording Using Multi-layer Photopolymer: Part II. Experimental Results, Journal of the Optical Society of America A, 36, 334–344, (2019). (SCI, IF=1.791) DOI: https://doi.org/10.1364/JOSAA.36.000334 Haoyu Li, Yue Qi, Changliang Guo, Ra’ed Malallah, and John T. Sheridan. Holographic characterization of diffraction grating modulation in photopolymers, Applied Optics, 57, E107–E117, (2018). DOI: https://doi.org/10.1364/AO.57.00E107 Ra’ed Malallah, Haoyu Li, Inbarasan Muniraj, Derek Cassidy, Nebras Al-Attar, John J. Healy, and John T. Sheridan. Controlling the trajectories of self-written waveguides in photopolymer, Journal of the Optical Society of America B, 35, 2046–2056, (2018). (SCI, IF=2.18) DOI: https://doi.org/10.1364/JOSAB.35.002046 Changliang Guo, Dayan Li, Damien P. Kelly, Haoyu Li, James P. Ryle, and John T. Sheridan. Measuring refractive index of glass by using speckle, Applied Optics, 57, E205–E217 (2018). DOI: https://doi.org/10.1364/AO.57.00E205 Haoyu Li, Changliang Guo, Inbarasan Muniraj, Bryce C. Schroede, John T. Sheridan, and Shu Jia. Volumetric light-field encryption at the microscopic scale, Scientific Reports, 7, (2017). (SCI, IF=3.998) DOI: https://doi.org/10.1364/FIO.2017.JTu2A.94 Tongyu Ding, Jianjia Yi, Haoyu Li, Hailing Zhang, and Shah Nawaz Nawazburoklur. 3D field-shaping lens using all dielectric gradient refractive index materials, Scientific Reports, 7, (2017). (SCI, IF=3.998) DOI: https://doi.org/10.1038/s41598-017-00681-z Raed Malallah, Haoyu Li, Damien P. Kelly, John J. Healy and John T. Sheridan. A Review of Hologram Storage and Self-Written Waveguides Formation in Photopolymer Media, Polymers, 9, 337-371, (2017). (SCI, IF=3.426) DOI: https://doi.org/10.3390/polym9080337 Haoyu Li, Yongkang Dong, Pengbai Xu, Yue Qi, Changliang Guo, and John T. Sheridan. Beam self-cleanup by use of self-written waveguide generated by photopolymerization, Optics Letters, 40, 2981–2984, (2015). (SCI, IF=3.714, 中科院二区) DOI: https://doi.org/10.1364/OL.40.002981 Haoyu Li, Yue Qi, Raed Malallah, and John T. Sheridan. Modeling the nonlinear photoabsorptive behavior during self-written waveguide formation in a photopolymer, Journal of the Optical Society of America B, 32, 912–922, (2015). (SCI, IF=2.18) DOI: https://doi.org/10.1364/JOSAB.32.000912 Haoyu Li, Yue Qi, Jinxin Guo, John T. Sheridan. Analysis of the absorptive behavior of photopolymer materials. Part I. Theoretical modeling, Journal of Modern Optics, 62, 145–156, (2015). DOI: https://doi.org/10.1080/09500340.2014.960020 Haoyu Li, Yue Qi, Elen Tolstik, Jinxin Guo, John T. Sheridan. Analysis of the absorptive behavior of photopolymer materials. Part II. Experimental validation, Journal of Modern Optics, 62, 157–167, (2015). DOI: https://doi.org/10.1080/09500340.2014.972474 Haoyu Li, Yue Qi, and John T. Sheridan. Three-dimensional extended nonlocal photopolymerization driven diffusion model. Part I. Absorption, Journal of the Optical Society of America B, 31, 2638–2647, (2014). (SCI, IF=2.18) DOI: https://doi.org/10.1364/JOSAB.31.002638 Haoyu Li, Yue Qi, and John T. Sheridan. Three-dimensional extended nonlocal photopolymerization driven diffusion model. Part II. Photopolymerization and model development, Journal of the Optical Society of America B, 31, 2648–2656, (2014). (SCI, IF=2.18) DOI: https://doi.org/10.1364/JOSAB.31.002648 Haoyu Li, Yue Qi, James P. Ryle, and John T. Sheridan. Self-written waveguides in a dry acrylamide/polyvinyl alcohol photopolymer material, Applied Optics, 53, 8086–8094, (2014). DOI: https://doi.org/10.1364/AO.53.008086 Yue Qi, Haoyu Li, Elen Tolstik, Jinxin Guo, Michael R. Gleeson, and John T. Sheridan. PQ/PMMA photopolymer: Modelling post-exposure, Optics Communications, 338, 406–415, (2015). DOI: https://doi.org/10.1016/j.optcom.2014.10.010 Yue Qi, Haoyu Li, Jean Pierre Fouassier, Jacques Lalevée, John T. Sheridan. Comparison of a new photosensitizer with erythrosine B in an AA/PVA-based photopolymer material, Applied Optics, 53, 1052–1062, (2014). DOI: https://doi.org/10.1364/AO.53.001052 Yue Qi, Haoyu Li, Jinxin Guo, Michael R. Gleeson, and John T. Sheridan. Material response of photopolymer containing four different photosensitizers, Optics Communications, 320, 114–124, (2014). DOI: https://doi.org/10.1016/j.optcom.2014.01.026 Yue Qi, Haoyu Li, Elen Tolstik, Jinxin Guo, Michael R. Gleeson, Vladislav Matusevich, Richard Kowarschik, and John T. Sheridan,. Study of PQ/PMMA photopolymer. Part 1: theoretical modeling, Journal of the Optical Society of America B, 30, 3298–3307, (2013). (SCI, IF=2.18) DOI: https://doi.org/10.1364/JOSAB.30.003298 Yue Qi, Elen Tolstik, Haoyu Li, Jinxin Guo, Michael R. Gleeson, Vladislav Matusevich, Richard Kowarschik, and John T. Sheridan. Study of PQ/PMMA photopolymer. Part 2: experimental results, Journal of the Optical Society of America B, 30, 3308–3315, (2013). (SCI, IF=2.18) DOI: https://doi.org/10.1364/JOSAB.30.003308

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