个人简介
赵天意,博士、青年拔尖副教授、博士生导师、生物信息学系主任、生物信息技术研究院副院长。
1992年出生于黑龙江省哈尔滨市,2018-2020年间赴哈佛大学进行联合培养,归国后留校任职青年拔尖副教授。
主持国家重点研发计划课题1项、国家自然基金1项、哈工大青年人才项目1项、医工交叉项目1项。
研究领域
研究方向为复杂疾病分子特征识别、生物网络分析,旨在通过对深度学习、机器学习算法的创新性突破解决生物学问题
近期论文
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复杂疾病分子特征识别
Zhao T*.Multiple mutations of IFITM3 are associated with COVID-19 susceptibility[J].The Journal of infection, 2023. (一区,IF=36.5)
Zhao T, Lyu S, Lu G, et al. SC2disease: a manually curated database of Single-Cell Transcriptome for human diseases[J]. Nucleic Acid Research, 2020. (一区,IF=16.5)
Zhao T, Hu Y, Liang C. Deep-DRM: A computational Method for Identifying Disease-related Metabolites based on Graph Deep Learning Approaches[J]. Briefings in Bioinformatics, 2020. (一区,IF=11.6)
Peng J, Zhao T*. Reduction in TOM1 expression exacerbates Alzheimer’s disease[J]. Proceedings of the National Academy of Sciences, 2020, 117(8): 3915-3916. (一区,IF=11.2)
Zhao T, Hu Y, Zang T, Cheng L. MRTFB Regulates the Expression of NOMO1 in Colon[J]. Proceedings of the National Academy of Sciences. 2020, 117(14): 7568-7569. (一区,IF=11.2)
Zhao T, Hu Y, Zang T, et al. Identifying Protein Biomarkers in Blood for Alzheimer's Disease[J]. Frontiers in Cell and Developmental Biology, 2020, 8. (二区,IF=6.6)
Zhao T, Hu Y, Zang T, et al. Identifying Alzheimer’s disease-related proteins by LRRGD[J]. BMC bioinformatics, 2019, 20(18): 570. (二区,IF=3.2)
Zhao T, Hu Y, Zang T, Wang Y. Integrate GWAS, eQTL, and mQTL Data to Identify Alzheimer's Disease-Related Genes[J]. Frontiers in Genetics, 2019, 10, 1021. (二区,IF=4.6)
Zhao T, et al. Identifying Alzheimer's Disease-related miRNA Based on Semi-clustering[J]. Current Gene Therapy,2019.(三区,IF=4.2)
分子调控关系识别
Zhao T, Liu J, Zeng X et al. Prediction and collection of protein–metabolite interactions [J]. Briefings in Bioinformatics, 2021. (一区, IF=11.6)
Zhao T, Y Hu, L R. Valsdottir, et al. Identifying drug-target interactions based on Graph Convolutional Network and Deep Neural Network[J]. Briefings in Bioinformatics, 2020. (一区,IF=11.6)
Zhao T, Hu Y, Liang C. DeepLGP: A Novel Deep Learning Method for Prioritizing lncRNA Target Genes[J]. Bioinformatics, 2020.(一区,IF=6.9)
分子特征识别
Zhao T, Liang C, Zang T, et al. Identification of anticancer peptides based on Random Relevance Vector Machines[C]//2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2019: 1822-1827.(CCF B类会议)
Yuran Jia,...., Zhao T*. THItoGene: a deep learning method for predicting spatial transcriptomics from histological images[J], Briefings in Bioinformatics, 2023. (一区,IF=9.5)
Zhao T, Cheng L, Zang T, et al. Peptide-Major Histocompatibility Complex Class I Binding Prediction Based on Deep Learning With Novel Feature[J]. Frontiers in Genetics, 2019, 10. (二区,IF=4.6)
Zhao T, Zhang N, Ren J, et al. A novel method to identify pre-microRNA in various species knowledge base[C]//2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2016: 1679-1688. (CCF B类会议)
Zhao T, et al. A novel method to identify pre-microRNA in various species knowledge base on various species[J]. Journal of Biomedical Semantics(三区,IF=2.1)