个人简介
Kuikun Yang received his Doctoral Degree of Chemistry from University of Maryland, College Park in 2018 under the supervision of Prof. Zhihong Nie. In 2019, He joined NIH and University of Macau as a postdoctoral researcher under the joint supervision of Prof. Xiaoyuan Chen and Prof. Ruibing Wang. He joined the School of Life Science and Technology in Harbin Institute of Technology in 2021 as a professor.
His current research interests focus on the assembly of nanomaterials for the imaging, diagnosis and therapy of tumors. He has published a series of works in Journal of the American Chemical Society, Angewandte Chemie International Edition, Advanced Materials, Chemical Society Reviews, ACS Nano, Advanced Functional Materials, Nano Today and Biomaterials as the first author. Kuikun Yang has been selected as the member of Early Career Researcher Board of Materials Today Bio (IF: 10.761), Military Medical Research (IF: 34.915), Journal of Materials Science and Technology (IF: 10.32) and Asian Journal of Pharmaceutical Sciences (IF: 9.289). He is also a reviewer editor of Frontiers in Chemistry (IF:5.545).
Education
2013.9-2018.12 Chemistry University of Maryland, College Park Ph.D.
2010.9-2013.6 Biochemistry and Molecular Biology Ocean University of China MSc Degree
2006.9-2010.6 Biotechnology Ocean University of China BSc Degree
Work Experience
2020.2-2021.5 Postdoctoral Fellow State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Science, University of Macau
2019.3-2020.2 Postdoctoral Fellow National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
研究领域
Our research group focuses on the design, synthesis and biomedical applications of self-assembled nanomaterials. We are particularly interested in the construction of self-assembled nanomedicines for cancer diagnosis and therapy. Our current major projects include: 1) development of polyprodrug nanoassemblies for cancer immunotherapy and 2) construction of hybrid polymer-inorganic nanoassemblies for cancer treatment.
近期论文
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Cooperative Assembly of Magneto-Nanovesicles with Tunable Wall Thickness and Permeability for MRI-Guided Drug Delivery 作者 Kuikun Yang,# Yijing Liu,# Yi Liu, Qian Zhang, Chuncai Kong, Chenglin Yi, Zijian Zhou, Zhantong Wang, Guofeng Zhang, Yang Zhang, Niveen M. Khashab,* Xiaoyuan Chen* and Zhihong Nie* 发表时间 2018.3 期刊名称 Journal of the American Chemical Society 期卷 140: 4666
Supramolecular Polymerization-induced Nanoassemblies for Self-augmented Cascade Chemotherapy and Chemodynamic Therapy of Tumour 作者 Kuikun Yang,# Guocan Yu,# Zhiqing Yang, Ludan Yue, Xiangjun Zhang, Chen Sun, Jianwen Wei, Lang Rao, Xiaoyuan Chen* and Ruibing Wang* 发表时间 2021.8 期刊名称 Angewandte Chemie International Edition 期卷 60: 17570
Oxygen-Evolving Manganese Ferrite Nanovesicles for Hypoxia-Responsive Drug Delivery and Enhanced Cancer Chemoimmunotherapy 作者 Kuikun Yang,# Guocan Yu,# Rui Tian, Zijian Zhou, Hongzhang Deng*, Ling Li, Zhen Yang, Guofeng Zhang, Dahai Liu, Jianwen Wei, Ludan Yue, Ruibing Wang* and Xiaoyuan Chen* 发表时间 2021.3 期刊名称 Advanced Functional Materials 期卷 31: 2008078
A Hypoxia Responsive Nanoassembly for Tumor Specific Oxygenation and Enhanced Sonodynamic Therapy 作者 Kuikun Yang,# Ludan Yue,# Guocan Yu, Lang Rao, Rui Tian, Jianwen Wei, Zhiqing Yang,# Chen Sun, Xiangjun Zhang, Mengze Xu, Zhen Yuan, Xiaoyuan Chen* and Ruibing Wang* 发表时间 2021.8 期刊名称 Biomaterials 期卷 275: 120822
Enzyme-induced in vivo assembly of gold nanoparticles for imaging-guided synergistic chemo-photothermal therapy of tumor 作者 Kuikun Yang,# Yijing Liu,# Yin Wang,# Qilong Ren, Hongyu Guo, John B. Matson, Xiaoyuan Chen* and Zhihong Nie* 发表时间 2019.12 期刊名称 Biomaterials 期卷 223: 119460
Polymers and Inorganic Nanoparticles: A Winning Combination towards Assembled Nanostructures for Cancer Imaging and Therapy 作者 Kuikun Yang,# Shaoyi Zhang,# Jie He and Zhihong Nie* 发表时间 2021.2 期刊名称 Nano Today 期卷 36: 101046
Polyprodrug Nanomedicines: An Emerging Paradigm for Cancer Therapy 作者 Kuikun Yang,# Zhiqing Yang,# Guocan Yu*, Ruibing Wang* and Xiaoyuan Chen* 发表时间 2021.1 期刊名称 Advanced Materials 期卷 In press
An Enzyme-Free Signal Amplification Technique for Ultrasensitive Colorimetric Assay of Disease Biomarkers 作者 Haihang Ye,# Kuikun Yang,# Jing Tao, Yijing Liu, Qian Zhang, Sanaz Habibi, Zhihong Nie* and Xiaohu Xia* 发表时间 2017.2 期刊名称 ACS Nano 期卷 1.88333333333333
Biodegradable hollow manganese/cobalt oxide nanoparticles for tumor theranostics 作者 Qilong Ren,# Kuikun Yang,# Rujia Zou, Zhiping Wan, Zheyu Shen, Guangyu Wu, Zijian Zhou, Qianqian Ni, Wenpei Fan, Junqing Hu* and Yijing Liu* 发表时间 2019.11 期刊名称 Nanoscale 期卷 11: 23021
Engineering heterogeneity of precision nanoparticles for biomedical delivery and therapy 作者 Di Zheng,# Kuikun Yang# and Zhihong Nie* 发表时间 2021.5 期刊名称 View 期卷 20200067
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