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Tailored Fluorosurfactants through Controlled/Living Radical Polymerization for Highly Stable Microfluidic Droplet Generation Li, Xiangke, Tang, Shi-Yang, Zhang, Yang, Zhu, Jiayuan, Forgham, Helen, Zhao, Chun-Xia, Zhang, Cheng, Davis, Thomas P. and Qiao, Ruirui (2023). Tailored Fluorosurfactants through Controlled/Living Radical Polymerization for Highly Stable Microfluidic Droplet Generation. Angewandte Chemie International Edition. doi: 10.1002/anie.202315552
3D-printed liquid metal polymer composites as NIR-responsive 4D printing soft robot Zhang, Liwen, Huang, Xumin, Cole, Tim, Lu, Hongda, Hang, Jiangyu, Li, Weihua, Tang, Shi-Yang, Boyer, Cyrille, Davis, Thomas P. and Qiao, Ruirui (2023). 3D-printed liquid metal polymer composites as NIR-responsive 4D printing soft robot. Nature Communications, 14 (1) 7815. doi: 10.1038/s41467-023-43667-4
Exploring Peptido‐Nanocomposites in the Context of Amyloid Diseases Andrikopoulos, Nicholas, Tang, Huayuan, Wang, Yue, Liang, Xiufang, Li, Yuhuan, Davis, Thomas P. and Ke, Pu Chun (2023). Exploring Peptido‐Nanocomposites in the Context of Amyloid Diseases. Angewandte Chemie International Edition. doi: 10.1002/anie.202309958
Antifouling surface coatings for the next generation of nanomedicine: toward in vivo immune evasion Forgham, Helen, Liu, Liwei, Davis, Thomas P and Qiao, Ruirui (2023). Antifouling surface coatings for the next generation of nanomedicine: toward in vivo immune evasion. Nanomedicine. doi: 10.2217/nnm-2023-0316
Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology Aguado, Julio, Amarilla, Alberto A., Taherian Fard, Atefeh, Albornoz, Eduardo A., Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K., Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A., Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E., Parry, Rhys, Sng, Julian D. J., Isaacs, Ariel, Khromykh, Alexander A., Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P., Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N., Woodruff, Trent M., Mar, Jessica C. ... Wolvetang, Ernst J. (2023). Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology. Nature Aging, 1-15. doi: 10.1038/s43587-023-00519-6
Length-Dependent Cellular Internalization of Nanobody-Functionalized Poly(2-oxazoline) Nanorods Finnegan, John R., FitzGerald, Laura I., Chen, Moore Zhe, Warne, Nicole M., Yuen, Daniel, Davis, Thomas P., Johnston, Angus P. R. and Kempe, Kristian (2023). Length-Dependent Cellular Internalization of Nanobody-Functionalized Poly(2-oxazoline) Nanorods. Nano Letters. doi: 10.1021/acs.nanolett.3c03342
Nanoengineering liquid metal core–shell nanostructures Lu, Hongda, Tang, Shi‐Yang, Zhu, Jiayuan, Huang, Xumin, Forgham, Helen, Li, Xiangke, Shen, Ao, Yun, Guolin, Hu, Jinming, Zhang, Shiwu, Davis, Thomas P., Li, Weihua and Qiao, Ruirui (2023). Nanoengineering liquid metal core–shell nanostructures. Advanced Functional Materials 2311300. doi: 10.1002/adfm.202311300
Heterocyclic Molecules Tethered Branched Polymers with Innate Immune Stimulating Activity Zhao, Jiayu, Liu, Liping, Wang, Yibo, Huang, Zichao, Zhang, Yu, Qiao, Ruirui, Davis, Thomas P., Tang, Zhaohui, Song, Wantong and Chen, Xuesi (2023). Heterocyclic Molecules Tethered Branched Polymers with Innate Immune Stimulating Activity. Ccs Chemistry. doi: 10.31635/ccschem.023.202303214
Alzheimer's progenitor amyloid‐β targets and dissolves microbial amyloids and impairs biofilm function Ali, Syed Aoun, Chung, Ka Hang Karen, Forgham, Helen, Olsen, William P., Kakinen, Aleksandr, Balaji, Arunpandian, Otzen, Daniel E., Davis, Thomas Paul and Javed, Ibrahim (2023). Alzheimer's progenitor amyloid‐β targets and dissolves microbial amyloids and impairs biofilm function. Advanced Science, 10 (29) 2301423. doi: 10.1002/advs.202301423
Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies Forgham, Helen, Liu, Liwei, Zhu, Jiayuan, Javed, Ibrahim, Cai, Weibo, Qiao, Ruirui and Davis, Thomas P. (2023). Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies. Coordination Chemistry Reviews, 487 215172. doi: 10.1016/j.ccr.2023.215172
Engineered ferritin nanoparticle vaccines enable rapid screening of antibody functionalization to boost immune responses Vu, Mai N., Pilkington, Emily H., Lee, Wen Shi, Tan, Hyon‐Xhi, Davis, Thomas P., Truong, Nghia P., Kent, Stephen J. and Wheatley, Adam K. (2023). Engineered ferritin nanoparticle vaccines enable rapid screening of antibody functionalization to boost immune responses. Advanced Healthcare Materials, 12 (17) 2202595, 1-13. doi: 10.1002/adhm.202202595
Targeting endosomal receptors, a new direction for polymers in nanomedicine Ramirez-Garcia, Paulina D., Veldhuis, Nicholas A., Bunnett, Nigel W. and Davis, Thomas P. (2023). Targeting endosomal receptors, a new direction for polymers in nanomedicine. Journal of Materials Chemistry B, 11 (24), 5390-5399. doi: 10.1039/d3tb00156c
Magnetic iron oxide nanoparticles for brain imaging and drug delivery Qiao, Ruirui, Fu, Changkui, Forgham, Helen, Javed, Ibrahim, Huang, Xumin, Zhu, Jiayuan, Whittaker, Andrew K. and Davis, Thomas P. (2023). Magnetic iron oxide nanoparticles for brain imaging and drug delivery. Advanced Drug Delivery Reviews, 197 114822, 1-31. doi: 10.1016/j.addr.2023.114822
Mannan-decorated STING-activating vaccine carrier for spatial coordinative stimulating antigen-specific immune responses Liu, Liping, Zhao, Jiayu, Huang, Zichao, Xu, Yudi, Chen, Hongyu, Qiao, Ruirui, Song, Wantong, Tang, Zhaohui, Davis, Thomas P. and Chen, Xuesi (2023). Mannan-decorated STING-activating vaccine carrier for spatial coordinative stimulating antigen-specific immune responses. Fundamental Research. doi: 10.1016/j.fmre.2023.03.018
Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes Cao, Rong, Tang, Ning, Zhu, Yi, Chen, An, Li, Yumeng, Ge, Renbin, Li, Yuan, Huang, Zhongyi, Guo, Jiajing, Deng, Jiali, Lu, Hongwei, Lu, Ziwei, Forgham, Helen, Davis, Thomas P., Qiao, Ruirui and Wang, Zhongling (2023). Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes. Nano Research, 16 (7), 10034-10046. doi: 10.1007/s12274-023-5679-x
Zinc–Epigallocatechin-3-gallate Network-Coated Nanocomposites against the Pathogenesis of Amyloid-Beta Andrikopoulos, Nicholas, Li, Yuhuan, Nandakumar, Aparna, Quinn, John F., Davis, Thomas P., Ding, Feng, Saikia, Nabanita and Ke, Pu Chun (2023). Zinc–Epigallocatechin-3-gallate Network-Coated Nanocomposites against the Pathogenesis of Amyloid-Beta. ACS Applied Materials & Interfaces, 15 (6), 7777-7792. doi: 10.1021/acsami.2c20334
Star polymer nanomedicines─challenges and future perspectives Forgham, Helen, Zhu, Jiayuan, Qiao, Ruirui and Davis, Thomas P. (2022). Star polymer nanomedicines─challenges and future perspectives. ACS Applied Polymer Materials, 4 (10), 6784-6796. doi: 10.1021/acsapm.2c01291
Hydrophobicity regulates the cellular interaction of cyanine5-labeled poly(3-hydroxypropionate)-based comb polymers Mahmoud, Ayaat M., Nowell, Cameron J., Feeney, Orlagh, Van 'T Hag, Leonie, Davis, Thomas P. and Kempe, Kristian (2022). Hydrophobicity regulates the cellular interaction of cyanine5-labeled poly(3-hydroxypropionate)-based comb polymers. Biomacromolecules, 23 (9), 3560-3571. doi: 10.1021/acs.biomac.2c00303
Nanomaterials integrated 3D printing for biomedical application Zhang, Liwen, Forgham, Helen, Shen, Ao, Wang, Jiafan, Zhu, Jiayuan, Huang, Xumin, Tang, Shiyang, Xu, Chun, Davis, Thomas P. and Qiao, Ruirui (2022). Nanomaterials integrated 3D printing for biomedical application. Journal of Materials Chemistry B, 10 (37), 7473-7490. doi: 10.1039/d2tb00931e
Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer? Forgham, Helen, Kakinen, Aleksandr, Qiao, Ruirui and Davis, Thomas P. (2022). Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?. Exploration, 00 (6), 20220012. doi: 10.1002/exp.20220012
Protected amine-functional initiators for the synthesis of α-amine homo- and heterotelechelic poly(2-ethyl-2-oxazoline)s Mazrad, Zihnil A. I., Lai, May, Davis, Thomas P., Nicolazzo, Joseph A., Thurecht, Kristofer J., Leiske, Meike N. and Kempe, Kristian (2022). Protected amine-functional initiators for the synthesis of α-amine homo- and heterotelechelic poly(2-ethyl-2-oxazoline)s. Polymer Chemistry, 13 (30), 4436-4445. doi: 10.1039/d2py00649a
Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth Ma, Z., Wong, S.W., Forgham, H., Esser, L., Lai, M., Leiske, M.N., Kempe, K., Sharbeen, G., Youkhana, J., Mansfeld, F., Quinn, J.F., Phillips, P.A., Davis, T.P., Kavallaris, M. and McCarroll, J.A. (2022). Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth. Biomaterials, 285 121539, 121539. doi: 10.1016/j.biomaterials.2022.121539
All-in-one inorganic nanoagents for near-infrared-II photothermal-based cancer theranostics Zhang, L., Forgham, H., Huang, X., Shen, A., Davis, T.P., Qiao, R. and Guo, B. (2022). All-in-one inorganic nanoagents for near-infrared-II photothermal-based cancer theranostics. Materials Today Advances, 14 100226, 100226. doi: 10.1016/j.mtadv.2022.100226
Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain Latorre, Rocco, Ramírez-Garcia, Paulina D., Hegron, Alan, Grace, James L., Retamal, Jeffri S., Shenoy, Priyank, Tran, Mai, Aurelio, Luigi, Flynn, Bernard, Poole, Daniel P., Klein-Cloud, Rafael, Jensen, Dane D., Davis, Thomas P., Schmidt, Brian L., Quinn, John F., Whittaker, Michael R., Veldhuis, Nicholas A. and Bunnett, Nigel W. (2022). Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain. Biomaterials, 285 121536, 121536. doi: 10.1016/j.biomaterials.2022.121536
Zwitterionic amino acid-derived polyacrylates as smart materials exhibiting cellular specificity and therapeutic activity Leiske, Meike N., Mazrad, Zihnil. A. I., Zelcak, Aykut, Wahi, Kanu, Davis, Thomas P., McCarroll, Joshua A., Holst, Jeff and Kempe, Kristian (2022). Zwitterionic amino acid-derived polyacrylates as smart materials exhibiting cellular specificity and therapeutic activity. Biomacromolecules, 23 (6), 2374-2387. doi: 10.1021/acs.biomac.2c00143
Thiol-responsive lyotropic liquid crystals exhibit triggered phase re-arrangement and hydrogen sulfide (H2S) release Urquhart, Matthew C., Ercole, Francesca, Clulow, Andrew J., Davis, Thomas P., Whittaker, Michael R., Boyd, Ben J. and Quinn, John F. (2022). Thiol-responsive lyotropic liquid crystals exhibit triggered phase re-arrangement and hydrogen sulfide (H2S) release. Journal of Colloid and Interface Science, 613, 218-223. doi: 10.1016/j.jcis.2021.12.180
Engineering polymers via understanding the effect of anchoring groups for highly stable liquid metal nanoparticles Huang, Xumin, Xu, Tianhong, Shen, Ao, Davis, Thomas P., Qiao, Ruirui and Tang, Shi-Yang (2022). Engineering polymers via understanding the effect of anchoring groups for highly stable liquid metal nanoparticles. ACS Applied Nano Materials, 5 (5) acsanm.1c04138, 5959-5971. doi: 10.1021/acsanm.1c04138
Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice De Logu, Francesco, Nassini, Romina, Hegron, Alan, Landini, Lorenzo, Jensen, Dane D., Latorre, Rocco, Ding, Julia, Marini, Matilde, Souza Monteiro de Araujo, Daniel, Ramírez-Garcia, Paulina, Whittaker, Michael, Retamal, Jeffri, Titiz, Mustafa, Innocenti, Alessandro, Davis, Thomas P., Veldhuis, Nicholas, Schmidt, Brian L., Bunnett, Nigel W. and Geppetti, Pierangelo (2022). Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice. Nature Communications, 13 (1) 646. doi: 10.1038/s41467-022-28204-z
miR-99b-5p, miR-380-3p and miR-485-3p are novel chemosensitising miRNAs in high-risk neuroblastoma Holliday, Holly, Yang, Jessica, Dodson, Eoin, Nikolic, Iva, Kamili, Alvin, Wheatley, Madeleine, Deng, Niantao, Alexandrou, Sarah, Davis, Thomas P., Kavallaris, Maria, Caldon, C. Elizabeth, McCarroll, Joshua, De Preter, Katleen, Mestdagh, Pieter, Marshall, Glenn M., Simpson, Kaylene J., Fletcher, Jamie and Swarbrick, Alexander (2022). miR-99b-5p, miR-380-3p and miR-485-3p are novel chemosensitising miRNAs in high-risk neuroblastoma. Molecular Therapy, 30 (3), 1119-1134. doi: 10.1016/j.ymthe.2022.01.004
Graphene quantum dots obstruct the membrane axis of Alzheimer's amyloid beta Tang, Huayuan, Li, Yuhuan, Kakinen, Aleksandr, Andrikopoulos, Nicholas, Sun, Yunxiang, Kwak, Eunbi, Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2022). Graphene quantum dots obstruct the membrane axis of Alzheimer's amyloid beta. Physical Chemistry Chemical Physics, 24 (1), 86-97. doi: 10.1039/d1cp04246g
Heat-induced living crystallization-driven self-assembly: the effect of temperature and polymer composition on the assembly and disassembly of poly(2-oxazoline) nanorods Finnegan, John R., Davis, Thomas P. and Kempe, Kristian (2022). Heat-induced living crystallization-driven self-assembly: the effect of temperature and polymer composition on the assembly and disassembly of poly(2-oxazoline) nanorods. Macromolecules, 55 (9), 3650-3660. doi: 10.1021/acs.macromol.2c00298
Spatio-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density Ahmed-Cox, Aria, Pandzic, Elvis, Johnston, Stuart T., Heu, Celine, McGhee, John, Mansfeld, Friederike M., Crampin, Edmund J., Davis, Thomas P., Whan, Renee M. and Kavallaris, Maria (2022). Spatio-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density. Journal of Controlled Release, 341, 661-675. doi: 10.1016/j.jconrel.2021.12.014
Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules Hu, Jinming, Fang, Yuanmeng, Huang, Xumin, Qiao, Ruirui, Quinn, John F. and Davis, Thomas P. (2021). Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules. Advanced Drug Delivery Reviews, 179 114005, 114005. doi: 10.1016/j.addr.2021.114005
Ex vivo culture of intact human patient derived pancreatic tumour tissue Kokkinos, John, Sharbeen, George, Haghighi, Koroush S., Ignacio, Rosa Mistica C., Kopecky, Chantal, Gonzales-Aloy, Estrella, Youkhana, Janet, Timpson, Paul, Pereira, Brooke A., Ritchie, Shona, Pandzic, Elvis, Boyer, Cyrille, Davis, Thomas P., Butler, Lisa M., Goldstein, David, McCarroll, Joshua A. and Phillips, Phoebe A. (2021). Ex vivo culture of intact human patient derived pancreatic tumour tissue. Scientific Reports, 11 (1) 1944, 1944. doi: 10.1038/s41598-021-81299-0
Dynamic protein corona of gold nanoparticles with an evolving morphology Nandakumar, Aparna, Wei, Wei, Siddiqui, Ghizal, Tang, Huayuan, Li, Yuhuan, Kakinen, Aleksandr, Wan, Xulin, Koppel, Kairi, Lin, Sijie, Davis, Thomas P., Leong, David T., Creek, Darren J., Ding, Feng, Song, Yang and Ke, Pu Chun (2021). Dynamic protein corona of gold nanoparticles with an evolving morphology. ACS Applied Materials and Interfaces, 13 (48), 58238-58251. doi: 10.1021/acsami.1c19824
Intrinsic green fluorescent cross-linked poly(ester amide)s by spontaneous zwitterionic copolymerization Zia, Aadarash, Finnegan, John R., Morrow, Joshua P., Yin, Wenping, Jasieniak, Jacek J., Pentzer, Emily, Thickett, Stuart, Davis, Thomas P. and Kempe, Kristian (2021). Intrinsic green fluorescent cross-linked poly(ester amide)s by spontaneous zwitterionic copolymerization. Biomacromolecules, 22 (11), 4794-4804. doi: 10.1021/acs.biomac.1c01087
Structure dependent differential modulation of Aβ fibrillization by selenadiazole-based inhibitors Kalsoom, Umme, Alazmi, Meshari, Farrukh, Hafiz Syed Usama Bin, Chung, Ka Hang Karen, Alshammari, Nawaf, Kakinen, Aleksandr, Chotana, Ghayoor Abbas, Javed, Ibrahim, Davis, Thomas Paul and Saleem, Rahman Shah Zaib (2021). Structure dependent differential modulation of Aβ fibrillization by selenadiazole-based inhibitors. ACS Chemical Neuroscience, 12 (20), 3806-3817. doi: 10.1021/acschemneuro.1c00478
A framework of paracellular transport via nanoparticles‐induced endothelial leakiness Lee, Myeongsang, Ni, Nengyi, Tang, Huayuan, Li, Yuhuan, Wei, Wei, Kakinen, Aleksandr, Wan, Xulin, Davis, Thomas P., Song, Yang, Leong, David Tai, Ding, Feng and Ke, Pu Chun (2021). A framework of paracellular transport via nanoparticles‐induced endothelial leakiness. Advanced Science, 8 (21) 2102519, e2102519. doi: 10.1002/advs.202102519
Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells Dao, Nam V., Ercole, Francesca, Li, Yuhuan, Davis, Thomas P., Kaminskas, Lisa M., Sloan, Erica K., Quinn, John F. and Whittaker, Michael R. (2021). Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells. Journal of Materials Chemistry B, 9 (37), 7805-7820. doi: 10.1039/d1tb00812a
Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticles Andrikopoulos, Nicholas, Song, Zhiyuan, Wan, Xulin, Douek, Alon M., Javed, Ibrahim, Fu, Changkui, Xing, Yanting, Xin, Fangyun, Li, Yuhuan, Kakinen, Aleksandr, Koppel, Kairi, Qiao, Ruirui, Whittaker, Andrew K., Kaslin, Jan, Davis, Thomas P., Song, Yang, Ding, Feng and Ke, Pu Chun (2021). Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticles. Chemistry of Materials, 33 (16) acs.chemmater.1c01947, 6484-6500. doi: 10.1021/acs.chemmater.1c01947
Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade Bondarenko, Olesja, Mortimer, Monika, Kahru, Anne, Feliu, Neus, Javed, Ibrahim, Kakinen, Aleksandr, Lin, Sijie, Xia, Tian, Song, Yang, Davis, Thomas P., Lynch, Iseult, Parak, Wolfgang J., Leong, David Tai, Ke, Pu Chun, Chen, Chunying and Zhao, Yuliang (2021). Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade. Nano Today, 39 101184, 101184. doi: 10.1016/j.nantod.2021.101184
Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition Sharbeen, George, McCarroll, Joshua A., Akerman, Anouschka, Kopecky, Chantal, Youkhana, Janet, Kokkinos, John, Holst, Jeff, Boyer, Cyrille, Erkan, Mert, Goldstein, David, Timpson, Paul, Cox, Thomas R., Pereira, Brooke A., Chitty, Jessica L., Fey, Sigrid K., Najumudeen, Arafath K., Campbell, Andrew D., Sansom, Owen J., Ignacio, Rosa Mistica C., Naim, Stephanie, Liu, Jie, Russia, Nelson, Lee, Julia, Chou, Angela, Johns, Amber, Gill, Anthony J., Gonzales-Aloy, Estrella, Gebski, Val, Guan, Yi Fang ... Phillips, Phoebe A. (2021). Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition. Cancer Research, 81 (13), 3461-3479. doi: 10.1158/0008-5472.CAN-20-2496
Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood Leiske, Meike N., Lai, May, Amarasena, Thakshila, Davis, Thomas P., Thurecht, Kristofer J., Kent, Stephen J. and Kempe, Kristian (2021). Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood. Biomaterials, 274 120843, 120843. doi: 10.1016/j.biomaterials.2021.120843
Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice Retamal, Jeffri S., Grace, Megan S., Dill, Larissa K., Ramirez-Garcia, Paulina, Peng, Scott, Gondin, Arisbel B., Bennetts, Felix, Alvi, Sadia, Rajasekhar, Pradeep, Almazi, Juhura G., Carbone, Simona E., Bunnett, Nigel W., Davis, Thomas P., Veldhuis, Nicholas A., Poole, Daniel P. and McIntyre, Peter (2021). Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice. Laboratory Investigation, 101 (7), 851-864. doi: 10.1038/s41374-021-00593-7
Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidity Li, Yuhuan, Tang, Huayuan, Zhu, Houjuan, Kakinen, Aleksandr, Wang, Di, Andrikopoulos, Nicholas, Sun, Yunxiang, Nandakumar, Aparna, Kwak, Eunbi, Davis, Thomas P., Leong, David Tai, Ding, Feng and Ke, Pu Chun (2021). Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidity. ACS Applied Materials and Interfaces, 13 (25) acsami.1c06478, 29936-29948. doi: 10.1021/acsami.1c06478
Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid beta Sun, Yunxiang, Kakinen, Aleksandr, Wan, Xulin, Moriarty, Niamh, Hunt, Cameron P.J., Li, Yuhuan, Andrikopoulos, Nicholas, Nandakumar, Aparna, Davis, Thomas P., Parish, Clare L., Song, Yang, Ke, Pu Chun and Ding, Feng (2021). Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid beta. Nano Today, 38 101125, 101125. doi: 10.1016/j.nantod.2021.101125
Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity Vu, Mai N., Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Esterbauer, Robyn, Davis, Thomas P., Truong, Nghia P., Wheatley, Adam K. and Kent, Stephen J. (2021). Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity. Advanced Healthcare Materials, 10 (10) 2002142, 1-12. doi: 10.1002/adhm.202002142
Polymeric micelles with anti-virulence activity against Candida albicans in a single- and dual-species biofilm Albayaty, Yassamin N., Thomas, Nicky, Ramirez-Garcia, Paulina D., Davis, Thomas P., Quinn, John F., Whittaker, Michael R. and Prestidge, Clive A. (2021). Polymeric micelles with anti-virulence activity against Candida albicans in a single- and dual-species biofilm. Drug Delivery and Translational Research, 11 (4), 1586-1597. doi: 10.1007/s13346-021-00943-4
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes Mai, Quynh N., Shenoy, Priyank, Quach, Tim, Retamal, Jeffri S., Gondin, Arisbel B., Yeatman, Holly R., Aurelio, Luigi, Conner, Joshua W., Poole, Daniel P., Canals, Meritxell, Nowell, Cameron J., Graham, Bim, Davis, Thomas P., Briddon, Stephen J., Hill, Stephen J., Porter, Christopher J.H., Bunnett, Nigel W., Halls, Michelle L. and Veldhuis, Nicholas A. (2021). A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes. Journal of Biological Chemistry, 296 100345, 100345. doi: 10.1016/J.JBC.2021.100345
Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes Xu, Xin, Huang, Xumin, Chang, Yixin, Yu, Ye, Zhao, Jiacheng, Isahak, Naatasha, Teng, Jisi, Qiao, Ruirui, Peng, Hui, Zhao, Chun-Xia, Davis, Thomas P., Fu, Changkui and Whittaker, Andrew K. (2021). Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes. Biomacromolecules, 22 (2), 330-339. doi: 10.1021/acs.biomac.0c01193
From influenza to COVID-19: lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases Pilkington, Emily H., Suys, Estelle J.A., Trevaskis, Natalie L., Wheatley, Adam K., Zukancic, Danijela, Algarni, Azizah, Al-Wassiti, Hareth, Davis, Thomas P., Pouton, Colin W., Kent, Stephen J. and Truong, Nghia P. (2021). From influenza to COVID-19: lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases. Acta Biomaterialia, 131, 16-40. doi: 10.1016/j.actbio.2021.06.023
In vitro and in vivo models for anti-amyloidosis nanomedicines Kakinen, Aleksandr, Javed, Ibrahim, Davis, Thomas P. and Ke, Pu Chun (2021). In vitro and in vivo models for anti-amyloidosis nanomedicines. Nanoscale Horizons, 6 (2), 95-119. doi: 10.1039/d0nh00548g
Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s Finnegan, John R., Pilkington, Emily H., Alt, Karen, Rahim, Md. Arifur, Kent, Stephen J., Davis, Thomas P. and Kempe, Kristian (2021). Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s. Chemical Science, 12 (21), 1-11. doi: 10.1039/d1sc00938a
Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model Dao, Nam V., Ercole, Francesca, Urquhart, Matthew C., Kaminskas, Lisa M., Nowell, Cameron J., Davis, Thomas P., Sloan, Erica K., Whittaker, Michael R. and Quinn, John F. (2021). Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model. Biomaterials Science, 9 (3), 835-846. doi: 10.1039/d0bm01544j
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