Qiao, Ruirui - The University of Queensland - Australian Institute for Bioengineering and Nanotechnology

个人简介

Dr Ruirui Qiao is a Group leader and NHMRC Emerging Leadership Fellow at Australian Institute for Bioengineering and Nanotechnology (AIBN), University of Queensland. Dr Qiao received her BSc (2005) and MSc (2007) in Peking University and was a tenured associate professor (2016–2017) and assistant professor (2009–2015) at the Institute of Chemistry, Chinese Academy of Sciences (CAS), where she received her PhD in 2014. In 2017, she joined ARC Centre of Bio-Nano Science (CBNS), Monash University as a project co-leader. Currently, she leads a nanobiotechnology research group at AIBN, focusing on the development of functional nanohybrids toward biomedical and clinical translations. She is currently serving as Associate Editor of Journal of Nanobiotechnology (BMC, Part of Spring Nature), and Guest Editors of Biosensors and Frontier in Pharmacology. Dr Qiao is looking for highly motivated Ph.D. students, and highly competitive full scholarship can be provided. The University of Queensland ranks in the top 50 as measured by the Performance Ranking of Scientific Papers for World Universities. The University also ranks 47 in the QS World University Rankings, 52 in the US News Best Global Universities Rankings, 60 in the Times Higher Education World University Rankings and 55 in the Academic Ranking of World Universities.

研究领域

Dr Qiao has made significant contributions to both research fields with work in synthetic methodology development, surface functionalisation, enhancing the physical properties of inorganic nanoparticles, as well as bioapplications in molecular imaging and drug delivery. She has publushed >80 peer reviewed articles in international top refereed journals such as ACS Nano, Chemistry of Materials, Advanced Materials, Polymer Chemistry, and so on., with citation >5400 times (H-index = 36). Her current research focuses on the development of improved molecular imaging agents based on the fabrication of inorganic nanomaterials with functional polymers for the controlled delivery of therapeutics and diagnostic agents. She received NHMRC Investigator Grant (2020) and UQ Foundation Research Excellence Award (2021).

近期论文

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Tailored Fluorosurfactants through Controlled/Living Radical Polymerization for Highly Stable Microfluidic Droplet Generation Li, Xiangke, Tang, Shi-Yang, Zhang, Yang, Zhu, Jiayuan, Forgham, Helen, Zhao, Chun-Xia, Zhang, Cheng, Davis, Thomas P. and Qiao, Ruirui (2023). Tailored Fluorosurfactants through Controlled/Living Radical Polymerization for Highly Stable Microfluidic Droplet Generation. Angewandte Chemie International Edition. doi: 10.1002/anie.202315552 3D-printed liquid metal polymer composites as NIR-responsive 4D printing soft robot Zhang, Liwen, Huang, Xumin, Cole, Tim, Lu, Hongda, Hang, Jiangyu, Li, Weihua, Tang, Shi-Yang, Boyer, Cyrille, Davis, Thomas P. and Qiao, Ruirui (2023). 3D-printed liquid metal polymer composites as NIR-responsive 4D printing soft robot. Nature Communications, 14 (1) 7815. doi: 10.1038/s41467-023-43667-4 Antifouling surface coatings for the next generation of nanomedicine: toward in vivo immune evasion Forgham, Helen, Liu, Liwei, Davis, Thomas P and Qiao, Ruirui (2023). Antifouling surface coatings for the next generation of nanomedicine: toward in vivo immune evasion. Nanomedicine. doi: 10.2217/nnm-2023-0316 Nanoengineering liquid metal core–shell nanostructures Lu, Hongda, Tang, Shi‐Yang, Zhu, Jiayuan, Huang, Xumin, Forgham, Helen, Li, Xiangke, Shen, Ao, Yun, Guolin, Hu, Jinming, Zhang, Shiwu, Davis, Thomas P., Li, Weihua and Qiao, Ruirui (2023). Nanoengineering liquid metal core–shell nanostructures. Advanced Functional Materials 2311300. doi: 10.1002/adfm.202311300 Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies Forgham, Helen, Liu, Liwei, Zhu, Jiayuan, Javed, Ibrahim, Cai, Weibo, Qiao, Ruirui and Davis, Thomas P. (2023). Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies. Coordination Chemistry Reviews, 487 215172. doi: 10.1016/j.ccr.2023.215172 Magnetic iron oxide nanoparticles for brain imaging and drug delivery Qiao, Ruirui, Fu, Changkui, Forgham, Helen, Javed, Ibrahim, Huang, Xumin, Zhu, Jiayuan, Whittaker, Andrew K. and Davis, Thomas P. (2023). Magnetic iron oxide nanoparticles for brain imaging and drug delivery. Advanced Drug Delivery Reviews, 197 114822, 1-31. doi: 10.1016/j.addr.2023.114822 Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes Cao, Rong, Tang, Ning, Zhu, Yi, Chen, An, Li, Yumeng, Ge, Renbin, Li, Yuan, Huang, Zhongyi, Guo, Jiajing, Deng, Jiali, Lu, Hongwei, Lu, Ziwei, Forgham, Helen, Davis, Thomas P., Qiao, Ruirui and Wang, Zhongling (2023). Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes. Nano Research, 16 (7), 10034-10046. doi: 10.1007/s12274-023-5679-x A reconfigurable and automatic platform for the on-demand production of stretchable conductive composites Lu, Hongda, Zhang, Qingtian, Huang, Xumin, Cole, Tim, Yun, Guolin, Zhang, Yuxin, Qiao, Ruirui, Li, Weihua and Tang, Shiyang (2023). A reconfigurable and automatic platform for the on-demand production of stretchable conductive composites. Smart Materials and Structures, 32 (4) 045018, 1-10. doi: 10.1088/1361-665x/acc221 Editorial: Smart materials for tumor-targeted drug/gene delivery Ding, Guobin, Zhang, Yinlong and Qiao, Ruirui (2023). Editorial: Smart materials for tumor-targeted drug/gene delivery. Frontiers in Materials, 10 1251599. doi: 10.3389/fmats.2023.1251599 Polymer-based synthetic oncolytic virus-like nanoparticles for cancer immunotherapy Gao, Yuxi, Zhao, Hanqin, Zhao, Jiayu, Ma, Sheng, Si, Xinghui, Liu, Liping, Qiao, Ruirui, Song, Wantong and Chen, Xuesi (2023). Polymer-based synthetic oncolytic virus-like nanoparticles for cancer immunotherapy. Science China Chemistry, 66 (12), 3576-3586. doi: 10.1007/s11426-023-1841-8 Connecting liquid metals with sound Qiao, Ruirui and Tang, Shi-Yang (2022). Connecting liquid metals with sound. Science (New York, N.Y.), 378 (6620), 594-595. doi: 10.1126/science.ade1813 Photoacoustic imaging probes for theranostic applications He, Cailing, Zhu, Jiayuan, Zhang, Huayue, Qiao, Ruirui and Zhang, Run (2022). Photoacoustic imaging probes for theranostic applications. Biosensors, 12 (11) 947, 1-21. doi: 10.3390/bios12110947 Star polymer nanomedicines─challenges and future perspectives Forgham, Helen, Zhu, Jiayuan, Qiao, Ruirui and Davis, Thomas P. (2022). Star polymer nanomedicines─challenges and future perspectives. ACS Applied Polymer Materials, 4 (10), 6784-6796. doi: 10.1021/acsapm.2c01291 Low-fouling gold nanorod theranostic agents enabled by a sulfoxide polymer coating Chang, Yixin, Wang, Qiaoyun, Xu, Weizhi, Huang, Xumin, Xu, Xin, Han, Felicity Y., Qiao, Ruirui, Ediriweera, Gayathri R., Peng, Hui, Fu, Changkui, Liu, Kun and Whittaker, Andrew K. (2022). Low-fouling gold nanorod theranostic agents enabled by a sulfoxide polymer coating. Biomacromolecules, 23 (9), 3866-3874. doi: 10.1021/acs.biomac.2c00696 Editorial: Protein-based nanocarriers for delivery of nutraceutical, diagnostic and therapeutic agents Zhong, Jian, Qiao, Ruirui and Yuan, Wei-En (2022). Editorial: Protein-based nanocarriers for delivery of nutraceutical, diagnostic and therapeutic agents. Frontiers in Pharmacology, 13 991474. doi: 10.3389/fphar.2022.991474 Nanomaterials integrated 3D printing for biomedical application Zhang, Liwen, Forgham, Helen, Shen, Ao, Wang, Jiafan, Zhu, Jiayuan, Huang, Xumin, Tang, Shiyang, Xu, Chun, Davis, Thomas P. and Qiao, Ruirui (2022). Nanomaterials integrated 3D printing for biomedical application. Journal of Materials Chemistry B, 10 (37), 7473-7490. doi: 10.1039/d2tb00931e Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer? Forgham, Helen, Kakinen, Aleksandr, Qiao, Ruirui and Davis, Thomas P. (2022). Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?. Exploration, 00 (6), 20220012. doi: 10.1002/exp.20220012 All-in-one inorganic nanoagents for near-infrared-II photothermal-based cancer theranostics Zhang, L., Forgham, H., Huang, X., Shen, A., Davis, T.P., Qiao, R. and Guo, B. (2022). All-in-one inorganic nanoagents for near-infrared-II photothermal-based cancer theranostics. Materials Today Advances, 14 100226, 100226. doi: 10.1016/j.mtadv.2022.100226 Engineering polymers via understanding the effect of anchoring groups for highly stable liquid metal nanoparticles Huang, Xumin, Xu, Tianhong, Shen, Ao, Davis, Thomas P., Qiao, Ruirui and Tang, Shi-Yang (2022). Engineering polymers via understanding the effect of anchoring groups for highly stable liquid metal nanoparticles. ACS Applied Nano Materials, 5 (5) acsanm.1c04138, 5959-5971. doi: 10.1021/acsanm.1c04138 Functional polymeric nanoparticles for drug delivery Qiao, Ruirui (2022). Functional polymeric nanoparticles for drug delivery. Current Pharmaceutical Design, 28 (5), 339-339. doi: 10.2174/138161282805220111142951 Recent advances in single Fe-based nanoagents for photothermal–chemodynamic cancer therapy Zhang, Li, Forgham, Helen, Shen, Ao, Qiao, Ruirui and Guo, Bing (2022). Recent advances in single Fe-based nanoagents for photothermal–chemodynamic cancer therapy. Biosensors, 12 (2) 86. doi: 10.3390/bios12020086 Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules Hu, Jinming, Fang, Yuanmeng, Huang, Xumin, Qiao, Ruirui, Quinn, John F. and Davis, Thomas P. (2021). Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules. Advanced Drug Delivery Reviews, 179 114005, 114005. doi: 10.1016/j.addr.2021.114005 Liquid metal particles and polymers: a soft–soft system with exciting properties Tang, Shi-Yang and Qiao, Ruirui (2021). Liquid metal particles and polymers: a soft–soft system with exciting properties. Accounts of Materials Research, 2 (10) accountsmr.1c00179, 966-978. doi: 10.1021/accountsmr.1c00179 Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticles Andrikopoulos, Nicholas, Song, Zhiyuan, Wan, Xulin, Douek, Alon M., Javed, Ibrahim, Fu, Changkui, Xing, Yanting, Xin, Fangyun, Li, Yuhuan, Kakinen, Aleksandr, Koppel, Kairi, Qiao, Ruirui, Whittaker, Andrew K., Kaslin, Jan, Davis, Thomas P., Song, Yang, Ding, Feng and Ke, Pu Chun (2021). Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticles. Chemistry of Materials, 33 (16) acs.chemmater.1c01947, 6484-6500. doi: 10.1021/acs.chemmater.1c01947 Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes Xu, Xin, Huang, Xumin, Chang, Yixin, Yu, Ye, Zhao, Jiacheng, Isahak, Naatasha, Teng, Jisi, Qiao, Ruirui, Peng, Hui, Zhao, Chun-Xia, Davis, Thomas P., Fu, Changkui and Whittaker, Andrew K. (2021). Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes. Biomacromolecules, 22 (2), 330-339. doi: 10.1021/acs.biomac.0c01193 Biomedical applications of liquid metal nanoparticles: a critical review Li, Haiyue, Qiao, Ruirui, Davis, Thomas P. and Tang, Shi-Yang (2020). Biomedical applications of liquid metal nanoparticles: a critical review. Biosensors, 10 (12) 196, 196. doi: 10.3390/bios10120196 Modular and integrated systems for nanoparticle and microparticle synthesis-a review Lu, Hongda, Tang, Shi-Yang, Yun, Guolin, Li, Haiyue, Zhang, Yuxin, Qiao, Ruirui and Li, Weihua (2020). Modular and integrated systems for nanoparticle and microparticle synthesis-a review. Biosensors, 10 (11) 165, 1-34. doi: 10.3390/bios10110165 Photo‐degradable micelles capable of releasing of carbon monoxide under visible light irradiation Zhang, Mingyang, Cheng, Jian, Huang, Xuming, Zhang, Guoying, Ding, Shenggang, Hu, Jinming and Qiao, Ruirui (2020). Photo‐degradable micelles capable of releasing of carbon monoxide under visible light irradiation. Macromolecular Rapid Communications, 41 (18) 2000323, 1-9. doi: 10.1002/marc.202000323 Magnetically-stimulated transformations in nanostructure of lipid mesophases: effect of structure of iron oxide nanoparticles Sun, Xiaohan, Alcaraz, Nicolas, Qiao, Ruirui, Hawley, Adrian, Tan, Angel and Boyd, Ben J. (2020). Magnetically-stimulated transformations in nanostructure of lipid mesophases: effect of structure of iron oxide nanoparticles. Colloids and Surfaces B: Biointerfaces, 191 110965, 110965. doi: 10.1016/j.colsurfb.2020.110965 Dynamic Temperature Control System for the Optimized Production of Liquid Metal Nanoparticles Lu, Hongda, Tang, Shi-Yang, Dong, Zixuan, Liu, Di, Zhang, Yuxin, Zhang, Chengchen, Yun, Guolin, Zhao, Qianbin, Kalantar-Zadeh, Kourosh, Qiao, Ruirui and Li, Weihua (2020). Dynamic Temperature Control System for the Optimized Production of Liquid Metal Nanoparticles. ACS Applied Nano Materials, 3 (7), 6905-6914. doi: 10.1021/acsanm.0c01257 Stimuli-responsive nano-assemblies for remotely controlled drug delivery Li, Fangyuan, Qin, Yu, Lee, Jiyoung, Liao, Hongwei, Wang, Nan, Davis, Thomas P., Qiao, Ruirui and Ling, Daishun (2020). Stimuli-responsive nano-assemblies for remotely controlled drug delivery. Journal of Controlled Release, 322, 566-592. doi: 10.1016/j.jconrel.2020.03.051 Engineering metal–organic frameworks (MOFS) for controlled delivery of physiological gaseous transmitters Zhang, Mengdan, Qiao, Ruirui and Hu, Jinming (2020). Engineering metal–organic frameworks (MOFS) for controlled delivery of physiological gaseous transmitters. Nanomaterials, 10 (6) 1134, 1-14. doi: 10.3390/nano10061134 Proteins conjugated with sulfoxide-containing polymers show reduced macrophage cellular uptake and improved pharmacokinetics Yu, Ye, Xu, Weizhi, Huang, Xumin, Xu, Xin, Qiao, Ruirui, Li, Yuhuan, Han, Felicity, Peng, Hui, Davis, Thomas P., Fu, Changkui and Whittaker, Andrew K. (2020). Proteins conjugated with sulfoxide-containing polymers show reduced macrophage cellular uptake and improved pharmacokinetics. ACS Macro Letters, 9 (6), 799-805. doi: 10.1021/acsmacrolett.0c00291 Sulfoxide‐containing polymer‐coated nanoparticles demonstrate minimal protein fouling and improved blood circulation Qiao, Ruirui, Fu, Changkui, Li, Yuhuan, Qi, Xiaole, Ni, Dalong, Nandakumar, Aparna, Siddiqui, Ghizal, Wang, Haiyan, Zhang, Zheng, Wu, Tingting, Zhong, Jian, Tang, Shi‐Yang, Pan, Shuaijun, Zhang, Cheng, Whittaker, Michael R., Engle, Jonathan W., Creek, Darren J., Caruso, Frank, Ke, Pu Chun, Cai, Weibo, Whittaker, Andrew K. and Davis, Thomas P. (2020). Sulfoxide‐containing polymer‐coated nanoparticles demonstrate minimal protein fouling and improved blood circulation. Advanced Science, 7 (13) 2000406, 2000406. doi: 10.1002/advs.202000406 Recent advances in molecular imaging of atherosclerotic plaques and thrombosis Qiao, Ruirui, Huang, Xumin, Qin, Yu, Li, Yuhuan, Davis, Thomas P., Hagemeyer, Christoph E. and Gao, Mingyuan (2020). Recent advances in molecular imaging of atherosclerotic plaques and thrombosis. Nanoscale, 12 (15), 8040-8064. doi: 10.1039/d0nr00599a Zero valent iron core–iron oxide shell nanoparticles as small magnetic particle imaging tracers Gloag, Lucy, Mehdipour, Milad, Ulanova, Marina, Mariandry, Kevin, Nichol, Muhammad Azrhy, Hernández-Castillo, Daniela J., Gaudet, Jeff, Qiao, Ruirui, Zhang, Ji, Nelson, Melanie, Thierry, Benjamin, Alvarez-Lemus, Mayra A., Tan, Thiam T., Gooding, J. Justin, Braidy, Nady, Sachdev, Perminder S. and Tilley, Richard D. (2020). Zero valent iron core–iron oxide shell nanoparticles as small magnetic particle imaging tracers. Chemical Communications, 56 (24), 3504-3507. doi: 10.1039/c9cc08972a Electrospraying technique and its recent application advances for biological macromolecule encapsulation of food bioactive substances Wang, Panpan, Ding, Mengzhen, Zhang, Ting, Wu, Tingting, Qiao, Ruirui, Zhang, Fengping, Wang, Xichang and Zhong, Jian (2020). Electrospraying technique and its recent application advances for biological macromolecule encapsulation of food bioactive substances. Food Reviews International, 38 (4), 566-588. doi: 10.1080/87559129.2020.1738455 Resorbable polymer electrospun nanofibers: history, shapes and application for tissue engineering Wu, Tingting, Ding, Mengzhen, Shi, Cuiping, Qiao, Yiqun, Wang, Panpan, Qiao, Ruirui, Wang, Xichang and Zhong, Jian (2020). Resorbable polymer electrospun nanofibers: history, shapes and application for tissue engineering. Chinese Chemical Letters, 31 (3), 617-625. doi: 10.1016/j.cclet.2019.07.033 Multimodal nanoprobe for pancreatic beta cell detection and amyloidosis mitigation Xin, Fangyun, Li, Yuhuan, Fu, Changkui, Javed, Ibrahim, Huang, Xumin, Schaschkow, Anais, Ribeiro, Rita S. Garcia, Gurzov, Esteban N., Davis, Thomas P., Zhang, Xiaoling, Ke, Pu Chun and Qjao, Ruirui (2020). Multimodal nanoprobe for pancreatic beta cell detection and amyloidosis mitigation. Chemistry of Materials, 32 (3), 1080-1088. doi: 10.1021/acs.chemmater.9b03841 A novel clustered SPIO nanoplatform with enhanced magnetic resonance T2 relaxation rate for micro-tumor detection and photothermal synergistic therapy Lu, Hongwei, Xu, Yongjing, Qiao, Ruirui, Lu, Ziwei, Wang, Pin, Zhang, Xindan, Chen, An, Zou, Liming and Wang, Zhongling (2020). A novel clustered SPIO nanoplatform with enhanced magnetic resonance T2 relaxation rate for micro-tumor detection and photothermal synergistic therapy. Nano Research, 13 (8), 2216-2225. doi: 10.1007/s12274-020-2839-0 Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis Li, Yuhuan, Xin, Fangyun, Hu, Jinming, Jagdale, Shweta, Davis, Thomas P., Hagemeyer, Christoph E. and Qiao, Ruirui (2020). Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis. Polymer Chemistry, 11 (5), 1010-1017. doi: 10.1039/c9py01568j