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个人简介

国宏哲,哈工大计算学部讲师、硕士生导师,黑龙江省头雁计划成员。主要研究方向:测序数据分析、序列比对与拼接、基因组变异检测、单细胞数据分析、生物大数据安全。在Journal of Infection(IF=38.637)Bioinformatics(IF=6.937)、BMC Bioinformatics(IF=3.307)等生物信息学顶级期刊发表多篇学术论文。主持国家自然科学基金青年项目一项、中国博士后科学基金面上项目一项。目前担任BMC Bioinformatics、IEEE-ACM Transactions on Computational Biology and Bioinformatics、Frontiers in Genetics等生物信息学期刊审稿人,黑龙江省计算机学会数据科学与大数据技术专业委员会。 教育经历 2006.09 – 2010.07 生物信息技术 哈尔滨工业大学 学士 2010.09 – 2012.07 计算机科学与技术 哈尔滨工业大学 硕士 2012.09 – 2019.04 计算机应用技术 哈尔滨工业大学 博士 2013.09 – 2014.12 美国杜克大学 生物信息学 联合培养博士 工作经历 星云生物信息技术开发有限公司 高级算法工程师 2019.05 – 2020.08 哈尔滨工业大学计算学部 师资博士后 讲师 2020.10 至今

研究领域

生物信息学 大规模基因组测序数据分析算法研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Hongzhe Guo, and Zhao, Tianyi. Multiple mutations of IFITM3 are associated with COVID-19 susceptibility. Journal of Infection, 10.1016/j.jinf.2023.02.032, 2023. (IF:38.637;中科院一区期刊) Hongzhe Guo#, Zhongbo Yang#, Tao Jiang, Shiqi Liu, Yadong Wang* and Zhe Cui*, Evaluation of classification in single cell atac-seq data with machine learning methods, BMC Bioinformatics, 23(5):249-259, 2022.(IF:3.307;中科院二区期刊) Hongzhe Guo#, Yilei Fu, Yan Gao, Junyi Li, Yadong Wang* and Bo Liu*, deGSM: memory scalable construction of large scale de Bruijn Graph, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 18(6):2157-2166, 2021.(IF:3.016;中科院二区期刊;CCF B类期刊) Ping Meng#, Guohua Wang, Hongzhe Guo* and Tao Jiang*, Identifying cancer driver genes using a two-stage random walk with restart on a gene interaction network, Computers in Biology and Medicine, 158(1):106810, 2023. (IF:7.7;中科院一区期刊) Tao Jiang#, Shiqi Liu#, Shuqi Cao, Yadong Liu, Zhe Cui, Yadong Wang* and Hongzhe Guo*, Long-read sequencing settings for efficient structural variation detection based on the comprehensive evaluation, BMC Bioinformatics, 22(1): 552-568, 2021.(通讯作者,IF:3.307;中科院二区期刊) Tao Jiang#, Shiqi Liu and Hongzhe Guo*. Reply: Correspondence on NanoVar’s performance outlined by Jiang T. et al. in ‘Long-read sequencing settings for efficient structural variation detection based on comprehensive evaluation, BMC Bioinformatics 24, 352 (2023).(通讯作者,IF:3.307;中科院二区期刊) 闫贞磊#, 国宏哲*, 面向大规模人群的基因组注释系统. Chinese Journal of Bioinformatics, 20(1), 2022.(通讯作者,全国中文核心期刊) Hongzhe Guo#, Bo Liu#, Dengfeng Guan, Yilei Fu and Yadong Wang*, Fast read alignment with incorporation of known genomic variants. BMC Medical Informatics and Decision Making, 2019, 19(6): 1-13.(IF:3.176;中科院三区期刊) Hongzhe Guo#, Bo Liu, Dengfeng Guan, Yilei Fu and Yadong Wang*, Fast variation-aware read alignment with deBGA-VARA, 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Madrid, 2018-12-3至2018-12-6. (CCF B类会议) Bo Liu#, Hongzhe Guo#, Michael Brudno and Yadong Wang*, deBGA: read alignment with de Bruijn graph-based seed and extension, Bioinformatics, 2016, 32(21): 3224-3232. (共同一作;IF:6.937;中科院一区期刊)

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