Sharrack, Basil - University of Sheffield - Department of Neuroscience

个人简介

Consultant Neurologist, Department of Neurosciences, Royal Hallamshire Hospital, Sheffield (January 1999 – Present time) Specialist Registrar, the National Hospital for Neurology and Neurosurgery, Queen Square, UCL, London (Feb 98 - Dec 98) Specialist Registrar, Department of Neurology, Chelsea & Westminster Hospital, Imperial Collage, London (Sept 97 - Jan 98) Clinical Research Fellow, United Medical and Dental Schools, Guy’s Hospital, King’s College, London (Jun 94 - Aug 97) Clinical Lecturer, Department of Neurology, Aleppo University Hospital, Aleppo University, Aleppo, Syria (Nov 93 - May 94) Career Registrar, Department of Clinical Neurology, Royal Hallamshire Hospital, Sheffield (Feb 91 - Oct 93)

研究领域

Neuro inflammation and degeneration with reference to multiple sclerosis Therapeutic clinical trials in multiple sclerosis Autologous Haematopoietic stem cell transplantation in multiple sclerosis Cognitive rehabilitation in multiples sclerosis Idiopathic intracranial hypertension

近期论文

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Association of nonmyeloablative hematopoietic stem cell transplantation with neurological disability in patients with relapsing-remitting multiple sclerosis. Burt RK, Balabanov R, Han X, Sharrack B, Morgan A, Quigley K, Yaung K, Helenowski IB, Jovanovic B, Spahovic D, Arnautovic I, Lee DC, Benefield BC, Futterer S, Oliveira MC, Burman J. The Journal of the American Medical Associating. 2015; 313(3):275-284. Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation. Wu D, Cerutti C, Lopez-Ramirez MA, Pryce G, King-Robson J, Simpson JE, van der Pol SM, Hirst MC, de Vries HE, Sharrack B, Baker D, Male DK, Michael GJ, Romero IA. Journal of Cerebral Blood Flow and Metabolism. 2015;35(3):412-423. MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. Lopez-Ramirez MA, Wu D, Pryce G, Simpson JE, Reijerkerk A, King-Robson J, Kay O, de Vries HE, Hirst MC, Sharrack B, Baker D, Male DK, Michael GJ, Romero IA. FASEB Journal. 2014;28(6):2551-265. Cost effectiveness of a pragmatic exercise intervention (EXIMS) for people with multiple sclerosis: economic evaluation of a randomised controlled trial. Tosh J, Dixon S, Carter A, Daley A, Petty J, Roalfe A, Sharrack B, Saxton J. Multiple Sclerosis. 2014;20(8):1123-1130. Pragmatic intervention for increasing self-directed exercise behaviour and improving important health outcomes in people with multiple sclerosis: a randomised controlled trial. Carter A, Daley A, Humphreys L, Snowdon N, Woodroofe N, Petty J, Roalfe A, Tosh J, Sharrack B, Saxton J. Multiple Sclerosis. 2014;20(8):1112-1122.