Alix, James - University of Sheffield - Department of Neuroscience

个人简介

2015 – Present: NIHR Academic Clinical Lecturer in Neurophysiology, University of Sheffield 2012 – 2014: Specialty Registrar in Clinical Neurophysiology, Yorkshire and the Humber Deanery 2010 – 2012: NIHR Academic Clinical Fellowship in Core Medical Training/Neurology, University of Sheffield 2008 – 2010: Academic Foundation Programme, Imperial College, London 2000 – 2008: MB/PhD programme, University of Leicester Medical School I studied medicine at Leicester Medical School, completing an intercalated BSc in neuroscience (1st class Hons) before moving onto the MB/PhD programme. I completed my PhD under the supervision of Prof. Robert Fern (now Univ. of Plymouth) on the molecular mechanisms of perinatal white matter injury. After graduating I gained further research experience in the laboratory of Prof Stephen Back (OHSU, USA) before commencing academic foundation programme training in London. Alongside clinical work I completed a research attachment with Prof. Richard Reynolds (Imperial College, London) before moving to Sheffield to take up an NIHR academic clinical fellowship. Since arriving in Sheffield I have continued my training as a clinician-scientist under the supervision of Prof. Dame Pamela Shaw.

研究领域

My main research is focused on the development of new techniques to diagnose and monitor neuromuscular disorders. I use electrophysiological techniques in both pre-clinical and clinical settings in order to better understand how these diseases start and change over time. I also have a long standing interest in perinatal brain injury.

近期论文

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Alix JJ, Hadjivassiliou M, Ali R, Slater D, Messenger AG, Rao DG. Sensory ganglionopathy with livedoid vasculopathy controlled by immunotherapy. Muscle Nerve. 2015;51(2):296-301 Alix JJ, Kandler RH, Mordekar SR. The value of long term EEG monitoring in children: a comparison of ambulatory EEG and video telemetry. Seizure. 2014;23(8):662-5. Goodwin E, Kandler RH, Alix JJ. The value of home video with ambulatory EEG: a prospective service review. Seizure. 2014;23(6):480-2 Alix JJ, Zammit C, Riddle A, Meshul CK, Back SA, Valentino M, Fern R. Central axons preparing to myelinate are highly sensitive to ischemic injury. Ann Neurol. 2012;72(6):936-51 Alix JJ, Domingues AM. White matter synapses: form, function, and dysfunction. Neurology. 2011;76(4):397-404 Alix JJ. Clinician-scientist training: a perspective from across the pond. Ann Neurol. 2010;68(1):119-20 Alix JJ, Fern R. Glutamate receptor-mediated ischemic injury of premyelinated central axons. Ann Neurol. 2009;66(5):682-93