张磊 - 中国科学院精密测量科学与技术创新研究院 -

个人简介

学习经历 2007年09月-2011年06月四川大学学士 2012年09月-2017年08月美国德克萨斯大学达拉斯分校博士工作经历 2018年01月-2021年08月中国科学院长春应用化学研究所副研究员 2021年08月-至今中国科学院精密测量与技术创新研究院研究员获奖及荣誉 2022年入选武汉英才计划

研究领域

小分子磁共振造影剂的研发及活体应用

近期论文

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Haonan He, Long Xiao, Kelu Zhao, Yi Zhang, Yi Cheng, Shizhen Chen, Lei Zhang,* Xin Zhou* and Kai Liu*, Hongjie Zhang. Detection and chiral recognition of α‐hydroxyl acid through proton and CEST NMR using Yb macrocyclic complex. Angew Chem Int Edit. 2019., 58,18286 –18289 Lei Zhang？ , André F. Martins？ , Piyu Zhao, Michael Tieu, David Esteban-Gómez, Gregory T. McCandless, Carlos Platas-Iglesias and A. Dean Sherry*. Enantiomeric recognition of D- and L-lactate by CEST with the aid of a paramagnetic shift reagent. J Am Chem Soc 2017, 139(48): 17431~17437 Lei Zhang？ , André F. Martins？ , Piyu Zhao, Yunkou Wu, Gyula Tircso, Dean Sherry*. Lanthanide-based T2ex and CEST complexes provide new insights into the design of pH sensitive MRI agents. Angew Chem Int Edit. 2017.12.4, 56(52): 16626~16630 Lei Zhang？ , André F. Martins？ , Yuyan Mai, Piyu Zhao, Alexander Funk, M. Veronica Clavijo Jordan, Shanrong Zhang, Wei Chen, Yunkou Wu and A. Dean Sherry*. Imaging extracellular lactate in vitro and in vivo using CEST MRI and a paramagnetic shift reagent. Chem-Eur J, 2017, 23 (8), 1752. Lei Zhang*; Jingjing Li; Kai Liu*, Recent advances in gadolinium-based MRI metal responsive agent, SCI China Technol SC, 2018.7.13, 61(9): 1329~1333 Yi Zhang, Kelu Zhao, Haonan He, Sikang Wan, Andre F. Martins, Lei Zhang*and Kai Liu. A T2ex MRI Dy-based contrast agent for direct pH imaging using a ratiometric approach. Dalton Trans.2021,50, 2014-2017 Sikang Wan, Fengzhi Cui, Bo Li, Kelu Zhao, Haonan He, Yi Zhang, Jianhua Liu, Lei Zhang*, and Kai Liu*. Dysprosium-Modified Gold Nanoparticles as T2ex Contrast Agents for Magnetic Resonance Imaging. ACS Appl. Nano Mater. 2020, 3, 9, 9433–9439 Yibin Yu, Yi Cheng, Junye Tong, Lei Zhang*, Yen Wei, Mei Tian. Recent advances in thermo-sensitive hydrogels for drug delivery. J. Mater. Chem. B, 2021,9, 2979-2992 Yang Liu, Wenyao Zhen, Yinghui Wang, Jianhua Liu, Longhai Jin, Tianqi Zhang, Songtao Zhang, Ying Zhao, Na Yin, Rui Niu, Shuyan Song, Lei Zhang, and Hongjie Zhang. Double Switch Biodegradable Porous Hollow Trinickel Monophosphide Nanospheres for Multimodal Imaging Guided Photothermal Therapy Nano Lett.2019, 198, 5093-5101 Chao Ma, Jing Sun, Bo Li, Yang Feng, Yao Sun, Li Xiang, Baiheng Wu, Lingling Xiao, Baimei Liu, Vladislav S. Petrovskii, Bin Liu, Jinrui Zhang, Zili Wang, Hongyan Li, Lei Zhang, Jingjing Li, Fan Wang, Robert G？stl, Igor I. Potemkin, Dong Chen, Hongbo Zeng, Hongjie Zhang, Kai Liu & Andreas Herrmann. Nat Commun .(2021) 12:3613