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个人简介

方超,副教授,博士生导师,哈尔滨工业大学(深圳)青年拔尖人才。长期致力于生物力学和软物质力学研究,主要方向为细胞与组织力学、生物材料和仿生力学、生物医用器件,特别关注细胞与组织形态演化的力学机理与调控方法,及其在生物医疗和仿生工程中的应用等力学、生物、材料交叉的科学问题。采用理论分析、数值模拟和实验验证结合的方式,近年在细胞与组织形态演化研究方面取得了一系列进展,相关研究成果先后发表于Science Advances、PNAS、JMPS、Biophysical Journal、Materials Horizons等期刊。 教育经历 2014.9-2018.12, 香港大学, 博士 2010.9-2014.7, 中国科学技术大学, 本科 工作经历 2022.10-至今, 哈尔滨工业大学(深圳), 副教授 2019.10-2022.10, 香港大学 , 博士后 2019.5-2019.8 , 国家纳米科学中心 , 研究助理 2018.10-2019.4 , 香港大学, 研究助理

研究领域

细胞与组织力学 生物材料与仿生力学 生物医用器件

近期论文

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F. Sun, C. Fang, X. Shao, H. Gao and Y. Lin. A mechanism-based theory of cellular and tissue plasticity. Proceedings of the National Academy of Sciences USA 120(44), e2305375120 (2023). C. Fang, X. Shao, Y. Tian, Z. Chu, Y. Lin, Size-dependent response of cells in epithelial tissue modulated by contractile stress fibers. Biophysical Journal 122, 1315-1324 (2023). C. Fang, J. Yao, Y. Zhang, Y. Lin, Active chemo-mechanical feedbacks dictate the collective migration of cells on patterned surfaces. Biophysical Journal 121, 1266-1275 (2022). Z. Yan, X. Xia, W. C. Cho, D. W. Au, X. Shao, C. Fang, Y. Tian, Y. Lin, Rapid Plastic Deformation of Cancer Cells Correlates with High Metastatic Potential. Advanced Healthcare Materials 11 (8), 2101657 (2022). C. Fang, J. Yao, X. Xia, Y. Lin, Modelling Nuclear Morphology and Shape Transformation: A Review. Membranes 11 (7), 540 (2021). C. Fang, X. Wei, X. Shao, Y. Lin, Force-mediated cellular anisotropy and plasticity dictate the elongation dynamics of embryos. Science Advances 7, eabg3264 (2021). X. Wei, C. Fang, B. Gong, X. Shao, F. Sun, J. Qian, Y. Lin, Time-dependent response of bio-polymer networks regulated by catch and slip bond-like kinetics of cross-linkers. Journal of the Mechanics and Physics of Solids 147, 104267 (2021). X. Shao, M. H. Srensen, C. Fang, R. C. C. Chang, Z. Chu, Y. Lin, Maturation of Neural Cells Leads to Enhanced Axon-Extracellular Matrix Adhesion and Altered Injury Response. Frontiers in Bioengineering and Biotechnology 8, 621777 (2021). X. Wei, C. Fang, B. Gong, J. Yao, J. Qian, Y. Lin, Viscoelasticity of 3D actin networks dictated by the mechanochemical characteristics of cross-linkers. Soft Matter 17 (45), 10177-10185 (2021). W. Yuan#, H. Wang#, C. Fang#, Y. Yang, X. Xia, B. Yang, Y. Lin, G. Li, L. Bian, Microscopic local stiffening in a supramolecular hydrogel network expedites stem cell mechanosensing in 3D and bone regeneration. Materials Horizons 8, 1722-1734 (2021). C. Fang, F. Zheng, J. Yao, X. Wei, C. Fu, X. Shi, Y. Lin, A model for bridging microtubule dynamics with nuclear envelope shape evolution during closed mitosis. Journal of the Mechanics and Physics of Solids 144, 104116 (2020). Z. Gong, C. Fang, R. You, X. Shao, R. C. C. Chang, Y. Lin, Forced peeling and relaxation of neurite governed by rate-dependent adhesion and cellular viscoelasticity. Extreme Mechanics Letters 40, 100902 (2020). X. Shao, M. H. Srensen, X. Xia, C. Fang, T. H. Hui, R. C. C. Chang, Z. Chu, Y. Lin, Beading of injured axons driven by tension-and adhesion-regulated membrane shape instability. Journal of the Royal Society Interface 17 (168), 20200331 (2020). H. Liu#, C. Fang#, Z. Gong, R. C.-C. Chang, J. Qian, H. Gao, Y. Lin, Fundamental characteristics of neuron adhesion revealed by forced peeling and time-dependent healing. Biophysical Journal 118, 1811-1819 (2020). X. Shao, R. You, T. H. Hui, C. Fang, Z. Gong, Z. Yan, R. C. C. Chang, V. B. Shenoy, Y. Lin, Tension-and adhesion-regulated retraction of injured axons. Biophysical Journal 117 (2), 193-202 (2019). Z. Gong#, C. Fang#, R. You, X. Shao, X. Wei, R. C. C. Chang, Y. Lin, Distinct relaxation timescales of neurites revealed by rate-dependent indentation, relaxation and micro-rheology tests. Soft Matter 15 (2), 166-174 (2019). C. Fang, T. H. Hui, X. Wei, Z. Yan, J. Qian, Y. Lin, Interaction and fusion dynamics between cellular blebs. Journal of Biomechanics 81, 113-121 (2018). C. Fang, T. H. Hui, X. Wei, X. Shao, Y. Lin, A combined experimental and theoretical investigation on cellular blebbing. Scientific Reports 7 (1), 16666 (2017).

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