Strutt, David - University of Sheffield - Department of Biomedical Science

个人简介

2005: Professor of Developmental Genetics 2003-present: Wellcome Senior Fellow in Basic Biomedical Science, University of Sheffield 1998-2003: Lister Institute-Jenner Research Fellow, University of Sheffield 1997-1998: Lecturer, University of Sheffield 1993-1997: Postdoctoral Fellow, European Molecular Biology Laboratory, Heidelberg 1991-1993: Postdoctoral Fellow, Department of Anatomy, University of Cambridge 1988-1991: PhD, Department of Anatomy, University of Cambridge 1985-1988: BA Natural Sciences, University of Cambridge

研究领域

Cell polarisation is a fundamental process in the development of complex multicellular organisms. We are interested in how such polarisation is coordinated and maintained during development, with a primary interest in the roles of the Frizzled sevenpass transmembrane receptor.

近期论文

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Saavedra P, Brittle A, Palacios IM, Strutt D, Casal J & Lawrence PA (2016) Planar cell polarity: the Dachsous/Fat system contributes differently to the embryonic and larval stages of Drosophila. Biology Open, 5(4), 397-408. View this article in White Rose Research Online Hale R & Strutt D (2015) Conservation of Planar Polarity Pathway Function Across the Animal Kingdom. Annual Review of Genetics, 49(1), 529-551. Hale R, Brittle AL, Fisher KH, Monk NAM & Strutt D (2015) Cellular interpretation of the long-range gradient of Four-jointed activity in the Drosophila wing. eLife, 4. View this article in White Rose Research Online Strutt H & Strutt D (2015) Planar Polarity: Forcing Cells Into Line. Current Biology, 25(21), R1032-R1034. Thomas C & Strutt D (2014) Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster.. Dev Biol, 385(1), 107-121. View this article in White Rose Research Online