Placzek, Marysia - University of Sheffield - Department of Biomedical Science

个人简介

2014-2015 Director of the Bateson Centre at the University of Sheffield (formerly, The MRC Centre for Developmental and Biomedical Genetics). 2009-2014 Acting Director, MRC Centre for Developmental and Biomedical Genetics 2007-2009 Deputy Director, MRC Centre for Developmental and Biomedical Genetics 1999-present: Professor in Developmental Neurobiology, University of Sheffield. 1997-1999: Senior Lecturer, University of Sheffield. 1992-1997: Scientific Staff, National Institute of Medical Research, London. 1983-1987: Post-doctoral fellow, Columbia University, New York. Research Advisor: Dr Jane Dodd. 1983-1987: PhD. Imperial Cancer Research Fund and Imperial College, London. Research Advisor: Dr Gordon Peters. 1979-1983: Bsc, University of Edinburgh.

研究领域

A major focus of our research is to understand the development of the vertebrate hypothalamus. We are aiming to characterise the signalling factor/transcription factor networks that mediate hypothalamic development, elucidate how hypothalamic stem cells progress into defined neuronal cells and how their axons project to different components of the hypothalamus. A second focus is the elucidation of the signalling factor/transcriptional networks that underlie development of the prechordal mesoderm.

近期论文

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Burbridge S, Stewart I & Placzek M (2016) Development of the Neuroendocrine Hypothalamus.. Compr Physiol, 6(2), 623-643. Ellis PS, Burbridge S, Soubes S, Ohyama K, Ben-Haim N, Chen C, Dale K, Shen MM, Constam D & Placzek M (2015) ProNodal acts via FGFR3 to govern duration of Shh expression in the prechordal mesoderm. Development, 142(22), 3821-3832. Liua F, Placzekb M & Xu H (2014) Corrigendum to "Axon guidance effect of classical morphogens Shh and BMP7 in the hypothalamo-pituitary system" [Neurosci. Lett. (2013) 104-109]. Neuroscience Letters, 562, 107. Robins SC, Stewart I, McNay DE, Taylor V, Giachino C, Goetz M, Ninkovic J, Briancon N, Maratos-Flier E, Flier JS, Kokoeva MV & Placzek M (2013) α-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors.. Nat Commun, 4, 2049. View this article in White Rose Research Online Placzek M & Anton ES (2013) Larysa Pevny, Ph.D., 1965-2012 Obituary. CELL STEM CELL, 12(1), 10-11. Liu F, Pogoda HM, Pearson CA, Ohyama K, Löhr H, Hammerschmidt M & Placzek M (2013) Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis.. Development, 140(5), 1111-1122. Liu F & Placzek M (2013) Axon guidance effects of classical morphogens Shh and BMP7 in the hypothalamo-pituitary system (DOI:10.1016/j.neulet.2013.08.027). Neuroscience Letters, 562, 108-113. Pearson CA & Placzek M (2013) Development of the medial hypothalamus: forming a functional hypothalamic-neurohypophyseal interface.. Curr Top Dev Biol, 106, 49-88.