Malicki, Jarema - University of Sheffield - Department of Biomedical Science

个人简介

2013-present: Reader, University of Sheffield 2012-present: Senior Research Fellow, University of Sheffield 1996-2010: Assistant Professor, Harvard Medical School, USA 1993-1996: Postdoctoral Fellow, Harvard Medical School, USA 1989-1993: Yale University, USA, Ph.D. 1987-1988: Bates College, USA 1983-1987: Warsaw University, Poland

研究领域

Eukaryotic cilia are fascinating highly polarized cell surface features that frequently detect and/or process extracellular signals, including small molecules, light, and polypeptides. We aim to understand how signal transduction mechanisms are assembled in cilia and how they function is processes as diverse as embryonic patterning, vision, and metabolism. The laboratory has also some interest in other aspects of cell polarity, such as membrane subcompartmentalization and organelle positioning in cell’s cytoplasm.

近期论文

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Malicki JJ & Johnson CA (2016) The Cilium: Cellular Antenna and Central Processing Unit. Trends in Cell Biology. Pooranachandran N & Malicki JJ (2016) Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins. Genetics, 203(2), 771-785. Jin D, Ni TT, Sun J, Wan H, Amack JD, Yu G, Fleming J, Chiang C, Li W, Papierniak A, Cheepala S, Conseil G, Cole SPC, Zhou B, Drummond IA, Schuetz JD, Malicki J & Zhong TP (2014) Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nature Cell Biology, 16(9), 841-851.