赵洪友 - 北京理工大学 - 医学技术学院

个人简介

赵洪友博士长期从事新型医用光敏药物的研发和临床前评价，激光诊疗设备的研发以及光动力治疗肿瘤的机制研究。由顾瑛院士牵头，赵洪友博士主要负责的国内第一个新型二氢卟吩类光敏药物KAE已经完成临床前功能与安全性评价，即将开展临床试验。参与研发的 “倍频Nd：YV04激光光动力治疗仪” 已获国家食品药品监督管理局三类医疗器械认证（国食药监械(准)字2013第3240155号），光学相干成像仪已获北京食品药品监督管理局二类器械认证（京食药监械(准)字2014第2241232号）。以第一/通讯作者在国际医学期刊 Eur. J. Cancer 发表封面文章1篇；国际医用化学期刊 J. Med. Chem. J Mater. Chem. B ；在国际生物光子学期刊J. Photochem. and Photobio. B, Photodiagnosis Photodyn. Ther.等杂志发表论文多篇。教育培训经历 2011. 09-2014. 07 解放军总医院激光医学博士研究生 2008. 09-2011. 07 华南师范大学生物医学光子学硕士研究生 2004. 09-2008. 07 内蒙古大学生物学本科工作经历 2020.01-现在北京理工大学，医学技术学院，特别副研究员 2016.09-2019. 03 美国路易斯安那州州立大学，癌症研究中心博士后 2014.08-2016. 08 美国南阿拉巴马大学，米切尔癌症研究中博士后

研究领域

可逆光酸治疗肿瘤的机制研究；新型光敏剂的研发以及临床前的系统评价；无创光疗治疗阿尔茨海默症的谱效与量效关系研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Hongyou Zhao*, Haolin Liu, Lin Kang, Tianzhen Sun, Yidi Liu, Defu Chen and Ying Gu* et al. In vitro and in vivo evaluation of a chlorin-based photosensitizer KAE? for cancer treatment. Photodiagnosis Photodyn Ther. 2022. doi: https://doi.org/10.1016/j. pdpdt. Hongyou Zhao, Tengda Ji, Tianzhen Sun, Haolin Liu, Yidi Liu, Haixia Qiu and Ying Gu* et al. “Comparative study on photobiomodulation between 630 nm and 810 nm LED in diabetic wound healing both in vitro and in vivo” J. Innov. Opt. Heal. Sci. 2022. 15: 2250010-1-2250010-10. Hongyou Zhao, Yi Bin, Zhipin Liang, Adam I. Riker, and Yaguang Xi* et al. “Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer” Genes & Diseases. 2021. 8: 320-330. Li-Peng Zhang, Xianqiang Li, Hongyou Zhao*, Lin Kang Tianlong Liu and Yuxia Zhao* et al. “Ultra-high photoactive thiadiazolo [3,4-g] quinoxaline nanoparticles with active-targeting capability for deep photodynamic therapy” J. Mater. Chem. B. 2021. 9: 8330–8340. Hongyou Zhao, Rong Yin, Ying Wang, Ying Gu* et al. Modulating mitochondrial morphology enhances antitumor effect of 5-ALA-mediated photodynamic therapy both in vitro and in vivo. J. Photochem. and Photobio. B. 2017. 176: 81-91. Qianli Zou#, Hongyou Zhao#, Yuxia Zhao, Ying Gu*, et al. Effective Two-Photon Excited Photodynamic Therapy of Xenograft Tumors Sensitized by Water-Soluble Bis(arylidene)cycloalkanone Photosensitizers. J. Med. Chem. 2015, 58:7949?7958. Hongyou Zhao, Rong Yin, Ying Wang, Ying Gu* et al. In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy. Photodiagnosis Photodyn. Ther. 2014, 11: 204-212. Hongyou Zhao, Yucheng Wang, Haixia Qiu, Ying Gu*. 2014. Photodynamic therapy and anti-tumor immunity. Chinese Journal of Laser Medicine & Surgery, 2014, 23:34-38. Hongyou Zhao, Qun Chen, Da Xing*. 2011. New insights of mitochondria reactive oxygen species generation and cell apoptosis induced by low dose photodynamic therapy. Eur. J. Cancer, 2011, 47：2750-2761. EI Journal paper Hongyou Zhao, Bin Yi, Ruixia Ma and Yaguang Xi. MiR-182 is involved in sulindac anticancer activity in colon cancer. 2017 AACR Annual Meeting: Research Propelling Cancer Prevention and Cures. Washington, D.C Hongyou Zhao, Bin Yi, Hong Chang, Zhipin Liang, Ruixia Ma and Yaguang Xi. Sulindac inhibition of colon tumor cell growth through miR-182/FOXO3a/CyclinG2 signaling. 2016 AACR Precision Medicine Series: Cancer Cell Cycle-Tumor Progression and Therapeutic Response. Orlando FL. Hongyou Zhao, Jie Ren, Rong Yin, Ying Wang, Ying Gu. The mechanism of apoptosis induced by photodynamic therapy. 2012 SPIE-Photonics Asia Meeting. Beijing. 中文论文刘浩林，邱海霞，曾晶，赵洪友*，顾瑛* 新型二氢卟吩类光敏剂KAE介导的光动力疗法对HeLa细胞的杀伤作用，激光医学杂志，2022 DOI：10.13480/j.issn1003-9430.2021.0301 赵洪友；王钰铖；邱海霞；顾瑛* 光动力治疗与抗肿瘤免疫，激光医学杂志，2 014,23,34-38

学术兼职

中华医学会激光医学分会委员北京医学会激光医学分会委员同时还担任J. Photochem. and Photobio. B, Photodiagnosis Photodyn. Ther.等多个国际学术期刊审稿人