孙乃迪 - 北京理工大学 - 医学技术学院

个人简介

孙乃迪，中共党员，博士，北京理工大学医学技术学院预聘助理教授，特别副研究员，硕士生导师。孙乃迪博士在哈尔滨工业大学分别获得了电子科学与技术专业学士学位（2010）和物理电子学专业硕士学位（2012），并在美国弗吉尼亚大学（University of Virginia）获得了生物医学工程专业博士学位（2020），随后在美国圣路易斯华盛顿大学（Washington University in St. Louis）从事博士后的研究工作。2022年7月，孙乃迪博士全职加入北京理工大学医学技术学院，任职预聘助理教授。孙乃迪博士长期从事用于生物体内高分辨率结构、功能和代谢的多参数光声显微镜的仪器开发，及其在心血管疾病、肾脏科学、脑神经科学和癌症等诸多背景下的生物医学应用。作为主要或重要参与人参加了十余项科研项目，包括美国自然科学基金（NSF）、美国国立卫生研究院（NIH）基金、美国心脏协会（AHA）基金等，并与阿斯利康制药公司（AstraZeneca）保持了长期的合作关系。迄今共发表SCI学术论文20余篇，H因子为7，包括 Kidney International、IEEE Transactions on Medical Imaging、Neuroimage、Plastic and Reconstructive Surgery、Biomedical Optics Express 等，累计引用476次。受邀参与撰写专著《The Vasculome: From Many, One》，已由 Elsevier Science 出版发行。孙乃迪博士目前是国际光电工程学会（SPIE）会员和美国心脏协会（AHA）会员，并担任 Light: Science & Application，Biomedical Optics Express，Scientific Report 等期刊评审。教育培训经历 2015.06-2020.08：弗吉尼亚大学，生物医学工程，博士 2010.09-2012.07：哈尔滨工业大学，物理电子学，硕士 2006.09-2010.07：哈尔滨工业大学，电子科学与技术，学士工作经历 2022.07-至今：北京理工大学，医学技术学院，预聘助理教授（特别副研究员），硕士生导师 2020.10-2022.06：圣路易斯华盛顿大学，生物医学工程系，博士后研究员

研究领域

1. 用于生物体内高分辨率结构、功能和代谢的成像系统开发新一代高时空分辨率、高穿透深度、高功能/分子对比度的光声成像结合光学、光声、超声等方法的多模态成像非侵入式近红外脑成像成像仪器/系统的小型化、可穿戴化、产品化 2. 用于成像系统后端的图像处理及对应算法研究高鲁棒性三维血管分割算法提高成像系统时空分辨率的机器学习相关算法数据及图像处理相关算法 3. 脑科学/心血管科学/肾脏学/肿瘤学等背景下的生物医学应用结合尖端成像/传感技术和分子/遗传操作的动物模型研究已验证的成像系统及相关技术的临床转化

近期论文

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Naidi Sun, Anthony C. Bruce, Bo Ning, Rui Cao, Yiming Wang, Fenghe Zhong, Shayn M. Peirce, and Song Hu*. ""Photoacoustic Microscopy of Vascular Adaptation and Tissue Oxygen Metabolism during Cutaneous Wound Healing."" Biomedical Optics Express. 13.5 (2022): 2695-2706. Editors' Pick. DOI: 10.1364/boe.456198 Naidi Sun?, Shuqiu Zheng?, Diane L. Rosin, Heather Perry, Rui Cao, Mark D. Okusa*, and Song Hu*. ""Development of a Photoacoustic Microscopy Technique to Assess Peritubular Capillary Function and Oxygen Metabolism in the Mouse Kidney."" Kidney International. 100.3 (2021): 613-620. Featured on the cover. DOI: 10.1016/j.kint.2021.06.018 Vincent M. Sciortino?, Angela Tran?, Naidi Sun?, Rui Cao, Tao Sun, Yu-Yo Sun, Ping Yan, Fenghe Zhong, Yifeng Zhou, Chia-Yi Kuan, Jin-Moo Lee, and Song Hu*. ""Longitudinal Cortex-wide Monitoring of Cerebral Hemodynamics and Oxygen Metabolism in Awake Mice Using Multi-parametric Photoacoustic Microscopy."" Journal of Cerebral Blood Flow & Metabolism. 41.12 (2021): 3187-3199. DOI: 10.1177/0271678X211034096 Naidi Sun, Bo Ning, Anthony C. Bruce, Rui Cao, Scott A. Seaman, Tianxiong Wang, Regina Fritsche-Danielson, Leif G. Carlsson, Shayn M. Peirce, and Song Hu*. ""In Vivo Imaging of Hemodynamic Redistribution and Arteriogenesis across Microvascular Network."" Microcirculation. 27 (2020):e12598. Featured on the cover. DOI: 10.1111/micc.12598 Naidi Sun, Bo Ning, Kenny M. Hansson, Anthony C. Bruce, Scott A. Seaman, Chenchu Zhang, Michaela Rikard, Christopher A. DeRosa, Cassandra L. Fraser, Maria W?gberg, Regina Fritsche-Danielson, Johannes Wikstr?m, Kenneth R. Chien, Anna Lundahl, Mikko H?ltt?, Leif G. Carlsson, Shayn M. Peirce*, and Song Hu*. ""Modified VEGF-A mRNA Induces Sustained Multifaceted Microvascular Response and Accelerates Diabetic Wound Healing."" Scientific Reports. 8 (2018):17509. DOI:10.1038/s41598-018-35570-6 Yifeng Zhou, Naidi Sun, and Song Hu*. ""Deep Learning-powered Bessel-beam Multiparametric Photoacoustic Microscopy."" IEEE Transactions on Medical Imaging. Early Access (2022). DOI: 10.1109/TMI.2022.3188739 Yiming Wang, Fenghe Zhong, Naidi Sun, Zhiqiang Xu, Jun Li, Qian Liu, Zhengying Li, Zhiyi Zuo, and Song Hu*. ""High-speed Multi-parametric Photoacoustic Microscopy of Cerebral Hemodynamic and Metabolic Responses to Acute Hemodilution."" Optics letters. 47.8 (2022): 1988-1991. DOI: 10.1364/OL.444327 Andrés Norambuena*, Xuehan Sun, Horst Wallrabe, Ruofan Cao, Naidi Sun, Evelyn Pardo, Nutan Shivange, Dora Bigler Wang, Lisa A.Post, Heather A.Ferris, Song Hu, Ammasi Periasamy, George S.Bloom. ""SOD1 Mediates Lysosome-to-Mitochondria Communication and its Dysregulation by Amyloid-β Oligomers."" Neurobiology of Disease. 169 (2022): 105737. DOI:10.1016/j.nbd.2022.105737 Sushanth G. Sathyanarayana?, Zhuoying Wang?, Naidi Sun, Bo Ning, Song Hu*, and John A. Hossack*. ""Recovery of Blood Flow from Undersampled Photoacoustic Microscopy Data Using Sparse Modeling."" IEEE Transactions on Medical Imaging. 41.1 (2021): 103-120. DOI: 10.1109/TMI.2021.3104521 Rui Cao, Angela Tran, Jun Li, Zhiqiang Xu, Naidi Sun, Zhiyi Zuo, and Song Hu*. ""Hemodynamic and Oxygen-Metabolic Responses of the Awake Mouse Brain to Hypercapnia Revealed by Multi-parametric Photoacoustic Microscopy."" Journal of Cerebral Blood Flow & Metabolism. 41.10 (2021): 2628-2639. DOI: 10.1177/0271678X211010352 Patrick S. Cottler*, Naidi Sun, Jenna M. Thuman, Kendall MH Bielak, Lisa S. Salopek, Angela Pi?eros-Fernandez, Song Hu, and Chris A. Campbell. ""The Biointegration of a Porcine Acellular Dermal Matrix in a Novel Radiated Breast Reconstruction Model."" Annals of Plastic Surgery. 84.6S (2020): S417-S423. DOI: 10.1097/SAP.0000000000002277 Nabin Poudel, Shuqiu Zheng, Colleen M. Schinderle, Naidi Sun, Song Hu, and Mark D. Okusa*. ""Peritubular Capillary Oxygen Consumption in Sepsis-Induced AKI: Multi-parametric Photoacoustic Microscopy."" Nephron. 144.12 (2020): 621-625. DOI: 10.1159/000511167 Zhiqiang Xu, Naidi Sun, Rui Cao, Zhengying Li, Quan Liu, and Song Hu*. ""Cortex-wide Multiparametric Photoacoustic Microscopy Based on Real-time Contour Scanning."" Neurophotonics. 6.3 (2019): 035012. DOI: 10.1117/1.NPh.6.3.035012 Tianxiong Wang, Naidi Sun, Ruimin Chen, Qifa Zhou, and Song Hu*. ""Isotropic-resolution Photoacoustic Microscopy with Multi-angle Illumination."" Optics letters. 44.1 (2019): 1-4. DOI: 10.1364/OL.44.000001 Zhiqiang Xu, Yiming Wang, Naidi Sun, Zhengying Li, Song Hu*, and Quan Liu*. ""Parallel Computing for Quantitative Blood Flow Imaging in Photoacoustic Microscopy."" Sensors. 19.18 (2019): 4000. DOI: 10.3390/s19184000 Patrick S. Cottler*, J. Bryce Olenczak, Bo Ning, Scott A. Seaman, Jenna M. Thuman, Naidi Sun, Angela Pi?eros-Fernandez, Song Hu, Brent R. DeGeorge Jr, and Chris A. Campbell. ""Fenestration Improves Acellular Dermal Matrix Biointegration: An Investigation of Revascularization with Photoacoustic Microscopy."" Plastic and Reconstructive Surgery. 143.4 (2019): 971-981. DOI: 10.1097/PRS.0000000000005410 Rui Cao, Jun Li, Bo Ning, Naidi Sun, Tianxiong Wang, Zhiyi Zuo*, and Song Hu*. ""Functional and Oxygen-metabolic Photoacoustic Microscopy of the Awake Mouse Brain."" Neuroimage. 150 (2017): 77-87. DOI: 10.1016/j.neuroimage.2017.01.049 Tianxiong Wang, Naidi Sun, Rui Cao, Bo Ning, Ruimin Chen, Qifa Zhou, and Song Hu*. ""Multiparametric Photoacoustic Microscopy of the Mouse Brain with 300-kHz A-line Rate. Neurophotonics. 3.4 (2016): 045006. DOI: 10.1117/1.NPh.3.4.045006 Bo Ning, Naidi Sun, Rui Cao, Ruimin Chen, K. Kirk Shung, John A. Hossack, Jin-Moo Lee, Qifa Zhou, and Song Hu*. ""Ultrasound-aided Multi-parametric Photoacoustic Microscopy of the Mouse Brain."" Scientific Reports. 5.1 (2015): 1-7. DOI: 10.1038/srep18775 Bo Ning, Matthew J. Kennedy, Adam J. Dixon, Naidi Sun, Rui Cao, Brian T. Soetikno, Ruimin Chen, Qifa Zhou, K. Kirk Shung, John A. Hossack, and Song Hu*. ""Simultaneous Photoacoustic Microscopy of Microvascular Anatomy, Oxygen Saturation, and Blood Flow."" Optics letters. 40.6 (2015): 910-913. DOI: 10.1364/OL.40.000910 Equal contribution; * Corresponding author(s)