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个人简介

刘建丽,特别副研究员、硕导。博士毕业于中国科学院化学研究所,近年来研究工作主要致力于用先进的原位纳米表征技术和质谱分析方法,在近生理条件、活细胞单分子水平研究生物分子间的相互作用和解析生物分子结构,揭示疾病的发病机理及阐明药物的作用机制。此外,通过设计侧链结构可定义的类肽分子,实现类肽可控自组装,利用原位分析检测技术,在分子尺度上实时观察组装过程及成核生长机制,为仿生基元结构的可控组装提供理论指导。目前,以第一/共同第一作者在Advanced Materials, Nanoscale, Science China Materials和Science Bulletin等国际期刊发表论文6篇,著述专著1章;主持国家自然科学基金青年项目和中国博士后面上项目各1项。 教育培训经历 2011.9-2016.7 中国科学院化学研究所 博士 2006.9-2010.7 东北农业大学 学士 工作经历 2021.08 - 至今 北京理工大学 医工融合研究院 助理教授/特别副研究员 2019.03 - 2021.07 东莞理工学院与西安交通大学联合培养博士后 2019.05 - 2021.05 美国西北太平洋国家实验室 访问学者 2016.10 - 2018.11 北京理工大学 博士后

研究领域

从事化学、材料科学、生物医学交叉学科的研究。主要方向为: 1. 仿生智能高分子水凝胶材料的构建及在生物医学(伤口敷料、骨再生修复等)中的应用 2. 基于水凝胶的细胞力学微环境构建及其对细胞行为的调控 3. 单细胞和分子水平研究细胞与生物材料的相互作用

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Jianli Liu, Bin Cai, Lifeng Cui* and Chun-Long Chen*, Peptoid-based hierarchically-structured biomimetic nanomaterials: synthesis, characterization and applications, Science China Materials, 2020, 63(7), 1099-1112. Shuai Zhang?*, Jiajun Chen?, Jianli Liu?, Harley Plyes, David Baker, Chun-Long Chen and James J. De Yoreo*, Engineering biomolecular self-assembly at solid-liquid interfaces, Advanced Materials, 2020, 1905784. (? co-first author) Jianli Liu, Wenhui Li, Xuejie Zhang, Yan Feng and Xiaohong Fang*, Ligand-receptor binding recognition: dynamic force spectroscopy applications, Methods in Molecular Biology, 2019, 1886:153-162. Jianli Liu?, Wei Tang?, Xiangzhi Meng, Lingpeng Zhan, Wei Xu*, Zongxiu Nie* and Zhonglin Wang*, Improving the performance of Mini 2000 mass spectrometer with a triboelectric nanogenerators electrospray ionization source, ACS Omega, 2018, 3, 12229-12234 Qiang Zhao?, Jianli Liu?, Bo Wang, Xiaohua Zhang, Guangyan Huang* and Wei Xu*, Rapid Screening of Explosives in Ambient Environment by Aerodynamic Assisted Thermo Desorption Mass Spectrometry, Journal of Mass Spectrometry, 2017,52,1-6. Jianli Liu, Xuejie Zhang, Xiaofeng Wang, Li Xu, Jingyuan Li and Xiaohong Fang*, Single-molecule force spectroscopy study of the effect of cigarette carcinogens on thrombomodulin-thrombin interaction, Science Bulletin,2016, 61, 1187–1194. Jianli Liu, Xuejie Zhang, Hang Yang, Jinghe Yuan, Hongping Wei, Junping Yu* and Xiaohong Fang*, Study of the interactions between endolysin and bacterial peptidoglycan on S. aureus by dynamic force spectroscopy, Nanoscale, 2015, 28, 17743-17748. Chengan Guo, Zhaoyin Diao, Jianli Liu, Baokun Yang and Jian Zhang*, Quantification and evaluation of ion transmission efficiency in two-stage vacuum chamber miniature mass spectrometer, Journal of Mass Spectrometry, 2022, doi.org/10.1002/jms.4816 Qiuling Zhao, Zhen Zhang, Li Xu, Tie Xia, Nan Li, Jianli Liu and Xiaohong Fang*, Exonuclease I aided enzyme-linked aptamer assay for small-molecule detection, Analytical and Bioanalytical Chemistry, 2014, 406, 2949-2955. Jianqiang Yu, Jinghe Yuan, Xuejie Zhang, Jianli Liu and Xiaohong Fang*, Nanoscale imaging with an integrated system combining stimulated emission depletion microscope and atomic force microscope, Science Bulletin, 2013, 58, 4045-4050. Han Xiao, Jianshu Zhang, Zhonghe Xu, Yenan Feng, Mingliang Zhang, Jianli Liu, Ruifei Chen, Jing Shen, Jimin Wu, Zhizhen Lu, Xiaohong Fang, Jingyuan Li, Youyi Zhang*, Old medicine, new target: metformin is an antagonist for transforming growth factor (TGF)-β1, Scientific Reports, 2016, 6,28597.

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