李玉婧 - 北京理工大学 - 医学技术学院

个人简介

李玉婧，北京理工大学助理教授（特别副研究员）。2018年获得吉林大学药学专业博士学位，在2016-2018年赴美国哈佛医学院进行科学研究，师从药物递送知名教授Omid C. Farokhzad和Jinjun Shi 教授。2019-2021年在国家纳米科学中心从事博士后研究，合作导师聂广军研究员。多年来从事新型给药系统的设计及研究，在智能缓控释纳米药物，微流控合成技术、纳米药物中试放大工艺及纳米药物的临床前体内外评价积累了较多的研究基础，近年来在Nano Letters, Advanced Materials, ACS Nano, Small, Nanomedicine, Bioconjugate Chemistry等杂志发表SCI论文14篇，具有药学、生物学、医学、化学、材料学等多学科的交叉研究背景。教育培训经历 2016.9-2018.9 哈佛医学院，访问学者 2012.9-2018.12，吉林大学，博士（药学） 2008.9-2012.6, 吉林大学，学士（药学）工作经历 2021.6-至今北京理工大学，医学技术学院/医工融合研究院 2019.3-2021.5 国家纳米科学中心，博士后

研究领域

天然高分子水凝胶/纳米生物材料在肿瘤免疫治疗与检测、骨与慢性创面修复及重大传染病防治的研究

近期论文

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Zhao Lin, Feng Zhipan, Lyu Yang, Yang Jueying, Lin Lizhi, Bai Haochen, Li Yujing*, Feng Yongqiang*, Chen Yu*. Electroactive injectable hydrogel based on oxidized sodium alginate and carboxymethyl chitosan for wound healing. Int J Biol Macromol. 2023 Mar 1;230:123231. Li Yujing#; Ding Jianxun#; Xu Xiaoding#; Shi Rui#; Saw Phei Er; Wang Junqing; Chung Shirley; Li Wenliang; Aljaeid Bader M; Lee Robert J.; Tao Wei; Teng Lesheng*; Farokhzad Omid C.*; Shi Jinjun*; Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy. Nano Letters, 2020, 20 (7), 4857-4863. Li Yujing; Wang Xudong; Zhang Yinlong; Nie Guangjun*; Recent Advances in Nanomaterials with Inherent Optical and Magnetic Properties for Bioimaging and Imaging-Guided Nucleic Acid Therapy. Bioconjugate Chemistry, 2020, 31 (5), 1234-1246. Li Yujing; Lee Robert J.; Huang Xueqin; Li Yuhuan; Lv Bingcong; Wang Tianpeng; Qi Yuhang; Hao Fei; Lu Jiahui; Meng Qingfan; Teng Lirong; Zhou Yulin; Xie Jing*; Teng Lesheng*; Single-step microfluidic synthesis of transferrin-conjugated lipid nanoparticles for siRNA delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 2017, 13 (2), 371-381. Li Yujing#; Huang Xueqin#; Lee Robert J.; Qi Yuhang; Wang Kaikai; Hao Fei; Zhang Yu; Lu Jiahui; Meng Qingfan; Li Shuai; Xie Jing*; Teng Lesheng*; Synthesis of Polymer-Lipid Nanoparticles by Microfluidic Focusing for siRNA Delivery. Molecules, 2016, 21 (10), 1314. Qu Na#; Sun Yating#; Li Yujing#; Hao Fei; Qiu Pengyu; Teng Lesheng; Xie Jing*; Gao Yin*. Docetaxel-loaded human serum albumin (HSA) nanoparticles: synthesis, characterization, and evaluation. BioMed Eng OnLine, 2019, 18: 11. Xiong Qingqing; Li Yujing; Zhou Kun; Chen Ping; Guo Hua; Chen Lu; Ding Jianxun*; Song Tianqiang*; Shi Jinjun; Optimized fluorodendrimer-incorporated hybrid lipid-polymer nanoparticles for efficient siRNA delivery. Biomaterials Science, 2020, 8 (3), 758-762. Li Yuhuan; Li Yujing; Wang Xinmei; Lee Robert J.; Teng Lesheng*; Fatty acid modified octa-arginine for delivery of siRNA. International Journal of Pharmaceutics, 2015, 495, 527-535. Li Yuhuan; Liu Da; Zhou Yulin; Li Yujing; Xie Jing; Lee Teng Lesheng*; Silencing of Survivin Expression Leads to Reduced Proliferation and Cell Cycle Arrest in Cancer Cells. Journal of Cancer, 2015, 6 (11), 1187-1194. Xu Xiaoding; Saw Phei Er; Tao Wei; Li Yujing; Ji Xiaoyuan; Yu Mikyung; Mahmoudi Morteza; Rasmussen Jonathan; Ayyash Dana; Zhou Yuxiao; Farokhzad Omid C.*; Shi Jinjun*; Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy. Nano Letters, 2017, 17 (7), 4427-4435. Xu Xiaoding#; Saw Phei Er#; Tao Wei; Li Yujing; Ji Xiaoyuan; Bhasin Sushant; Liu Yanlan; Ayyash Dana; Rasmussen Jonathan; Huo Macr; Shi Jinjun*; Farokhzad Omid C.*; ROS-Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy. Advanced Materials, 2017, 29 (33), 10.1002/adma.201700141. Cheng Keman#; Zhao Ruifang#; Li, Yao; Qi Yingqiu; Wang Yazhou; Zhang Yinlong; Qin Hao; Qin Yuting; Chen Long; Li Chen; Liang Jie; Li Yujing; Xu Jiaqi; Han Xuexiang; Anderson Gregory J.; Shi Jian; Ren Lei; Zhao Xiao*; Nie Guangjun*; Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology. Nature communications, 2021, 12 (1), 2041. Li Yao#; Zhao Ruifang#; Cheng Keman; Zhang Kaiyue; Wang Yazhou; Zhang Yinlong; Li Yujing; Liu Guangna; Xu Junchao; Xu Jiaqi; Anderson Gregory J; Shi Jian; Ren Lei; Zhao Xiao*; Nie Guangjun*; Bacterial Outer Membrane Vesicles Presenting Programmed Death 1 for Improved Cancer Immunotherapy via Immune Activation and Checkpoint Inhibition. ACS Nano, 2020. Xu Xiaoding; Wu Jun; Liu Shuaishuai; Saw Phei Er; Tao Wei; Li Yujing; Krygsman Lisa; Yegnasubramanian Srinivasan; Marzo Angelo M De; Shi Jinjun; Bieberich Charles J; Farokhzad Omid C.*; Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy. Small (Weinheim an der Bergstrasse, Germany), 2018, 14 (41), e1802565. Li Yuhuan; Lee Robert J.; Yu Kongtong; Bi Ye; Qi Yuhang; Sun Yating; Li Yujing; Xie Jing*; Teng Lesheng*; Delivery of siRNA Using Lipid Nanoparticles Modified with Cell Penetrating Peptide. ACS applied materials & interfaces, 2016, 8 (40), 26613-26621. 中文论文导电水凝胶及其在糖尿病创面修复中的应用研究进展[J]，中华烧伤与创面修复杂志(2023), 吕洋，褚万立，陈煜，李玉婧*，马西兰*；

学术兼职

2020年08月至今，BIO Integration期刊青年编委 2021年07月至今，中国抗癌协会会员