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个人简介

魏泽文,北京理工大学医学技术学院特别研究员/博士生导师。从事生物微系统(Bio-MEMS)领域研究,主要包括基于微流控芯片的类器官分析仪器和基于微针电极芯片的可穿戴器件研究。发表SCI论文50余篇,其中以(共同)通讯或第一作者发表中科院1区Top期刊31篇,H 因子17。授权发明专利17项。主持国家自然科学基金青年及面上、国家重点研发计划课题、首都卫生发展专项课题、国防相关项目等竞争性科研项目11项,项目经费1500余万元。 教育培训经历 2007-09至2011-07,北京大学,微电子学与固体电子学,理学博士 2004-09至2007-07,东南大学,微电子学与固体电子学,工学硕士 2000-09至2004-07,东南大学,电子科学与技术,工学学士 工作经历 2019-03至今,北京理工大学,生命学院/医学技术学院,特别研究员/博士生导师 2016-01至2016-12,哈佛医学院,布列根和妇女医院,国家公派访问学者 2015-03至2019-02,国家纳米科学中心,副研究员/硕士生导师 2011-07至2015-02,国家纳米科学中心,助理研究员

研究领域

用于生物医学的微电子机械系统(Biomedical Micro-Electro-Mechanical System),类器官芯片,可穿戴器件

近期论文

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部分论文 *第一作者 #通讯作者 Zhang K, Wang Y, Xue J, Liang N#, Wei Z#. Real-time monitoring ATP variation in human cancer organoids for a long term by DNA-based nanosensor. Anal Chim Acta. 2023, 22;1275:341608. 中科院1区Top期刊 Zhang K, Huang Z, Wang Y, Xue J, Liang N#, Wei Z#.Rapid determination of the presence of EGFR mutations with DNA-based nanocalipers. Nanoscale, 2023,15, 13834-13841. 中科院2区Top期刊 Zhao H, Wang X, Geng Z, Liang N, Li Q, Hu X#, Wei Z#. Dual-function microneedle array for efficient photodynamic therapy with transdermal co-delivered light and photosensitizers. Lab Chip. 2022 Nov 22;22(23):4521-4530. 中科院1区Top期刊 Zhang W, Li Q, Jia F, Hu Z, Wei Z#. A Microfluidic Chip for Screening and Sequencing of Monoclonal Antibody at a Single-Cell Level. Anal Chem. 2021 Jul 27;93(29):10099-10105. 中科院1区Top期刊 Zhang W, Li R, Jia F, Hu Z#, Li Q#, Wei Z# A microfluidic chip for screening high-producing hybridomas at single cell level. Lab Chip. 2020 Nov 7;20(21):4043-4051. 中科院1区Top期刊 Li R, Jia F, Zhang W, Shi F, Fang Z, Zhao H, Hu Z#, Wei Z#. Device for whole genome sequencing single circulating tumor cells from whole blood. Lab Chip. 2019 Sep 27;19(19):3168-3178. 中科院1区Top期刊 Li R, Ma Y, Zhao M, Hu Z#, Wei Z#. Device to Study the Cell Invasion Behavior and Phenotypic Profile at Single Cell Level. Anal Chem. 2018 Feb 6;90(3):1691-1700. 中科院1区Top期刊 Li R, Zhou M, Yue C, Zhang W, Ma Y, Peng H, Hu Z#, Wei Z#. Multiple single cell screening and DNA MDA amplification chip for oncogenic mutation profiling. Lab Chip. 2018 Feb 27;18(5):723-734. 中科院1区Top期刊 Zhao D, Wu M, Huang D, Liang Z#, Wei Z#, Li Z. Parametric optimization of electric field strength for cancer electrochemotherapy on a chip-based model. Theranostics. 2018 Jan 1;8(2):358-368. 中科院1区Top期刊 Li R, Zhou M, Li J, Wang Z, Zhang W, Yue C, Ma Y, Peng H, Wei Z#, Hu Z#. Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip. Nano-Micro Lett. 2018;10(1):16. 中科院1区Top期刊 Zhao M, Zhao D, Ma Y, Hu Z, Wei Z#. Quantitative Proteomic Analysis of Cell Responses to Electroporation, a Classical Gene Delivery Approach. Proteomics. 2018 Aug;18(16):e1800127. Zhang W, Li Z, Wang Z, Yue C, Zheng H, Li R, Zhou M, Hu Z#, Wei Z#, Li Q. Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 protein and its application on identifying circulating tumor cells. PLoS One. 2018 Feb 9;13(2):e0192506. Zhou M, Zheng H, Wang Z, Li R, Liu X, Zhang W, Wang Z, Li H, Wei Z#, Hu Z#. Precisely Enumerating Circulating Tumor Cells Utilizing a Multi-Functional Microfluidic Chip and Unique Image Interpretation Algorithm. Theranostics. 2017 Oct 17;7(19):4710-4721. 中科院1区Top期刊 Zhao D, Huang D, Li Y, Wu M, Zhong W, Cheng Q, Wang X, Wu Y, Zhou X, Wei Z*, Li Z#, Liang Z#. A Flow-Through Cell Electroporation Device for Rapidly and Efficiently Transfecting Massive Amounts of Cells in vitro and ex vivo. Sci Rep. 2016 Jan 5;6:18469. Ye M*, Wei Z*, Hu F, Wang J, Ge G, Hu Z, Shao M, Lee ST, Liu J. Fast assembling microarrays of superparamagnetic Fe3O4@Au nanoparticle clusters as reproducible substrates for surface-enhanced Raman scattering. Nanoscale. 2015 Aug 28;7(32):13427-37. 中科院2区Top期刊 Wei Z*, Huang Y*, Zhao D, Hu Z, Li Z, Liang Z. A pliable electroporation patch (ep-Patch) for efficient delivery of nucleic acid molecules into animal tissues with irregular surface shapes. Sci Rep. 2015 Jan 5;5:7618. Wang W*, Zhang D*, Wei Z*, Wang Z, Bu X, Yang S, Fang Q, Hu Z. Label-free detection microarray for novel peptide ligands screening base on MS-SPRi combination. Talanta. 2015 Mar;134:705-711. 中科院1区Top期刊 Wei Z*, Zheng S*, Wang R, Bu X, Ma H, Wu Y, Zhu L, Hu Z, Liang Z, Li Z. A flexible microneedle array as low-voltage electroporation electrodes for in vivo DNA and siRNA delivery. Lab Chip. 2014 Oct 21;14(20):4093-102. 中科院1区Top期刊 Wei Z*, Li X, Zhao D, Yan H, Hu Z, Liang Z, Li Z. Flow-through cell electroporation microchip integrating dielectrophoretic viable cell sorting. Anal Chem. 2014 Oct 21;86(20):10215-22. 中科院1区Top期刊 Wang W*, Wei Z*, Zhang D, Ma H, Wang Z, Bu X, Li M, Geng L, Lausted C, Hood L, Fang Q, Wang H, Hu Z. Rapid screening of peptide probes through in situ single-bead sequencing microarray. Anal Chem. 2014 Dec 2;86(23):11854-9. 中科院1区Top期刊

学术兼职

中国医疗保健国际交流促进会健康大数据和数字化医疗分会委员 中国初级卫生保健基金会检验医学研究与转化专业委员会首席科研专家

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