Guo, Chun - University of Sheffield - Department of Biomedical Science

个人简介

2015–Present: Lecturer, Department of Biomedical Science, University of Sheffield 2013 –2015: Research Fellow, School of Biochemistry, University of Bristol 2009 –2013: Senior Research Associate, School of Biochemistry, University of Bristol 2002 –2009: Research Associate, Faculty of Life Sciences, University of Manchester 1999–2002: PhD, Leicester School of Pharmacy, De Montfort University, U.K. 1996 –1999: Lecturer, Department of Human Anatomy, Medical College of Soochow University, China.

研究领域

My research interests are to understand the basic cell biology and signaling pathways associated with protein post-translational modifications (PTMs, e.g., Proteolytic Cleavage, Phosphorylation, Ubiquitination and SUMOylation) in cell death, survival and repair following stress, and to translate the findings into animal models of human diseases and into treatments for human disease.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Guo C and Henley JM. (2014) Wrestling with stress: roles of protein SUMOylation and deSUMOylation in cell stress response. IUBMB Life 66(2):71-7. Guo C, Hildick KL, Luo J, Dearden L, Wilkinson KA, Henley JM. (2013) SENP3-mediated DeSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia. EMBO J. 32(11):1514-28. Jin J, Zhao Y, Tan X, Guo C, Yang Z, Miao D. (2011) An improved transplantation strategy for mouse mesenchymal stem cells in an acute myocardial infarction model. PLoS One 6(6), e21005. Choudhury R, McGovern A, Ridley C, Cain SA, Baldwin A, Wang MC, Guo C, Mironov A Jr., Drymoussi Z, Trump D, Shuttleworth A, Baldock C and Kielty CM. (2009). Differential regulation of elastic fiber formation by fibulins -4 and -5. J. Biol. Chem. 284(36):24553-67. Guo C and Whitmarsh AJ. (2008). The b-arrestin-2 scaffold protein promotes c-Jun N-terminal kinase-3 activation by binding to its non-conserved N-terminus. J. Biol. Chem. 283(23):15903-11.