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个人简介

徐伟,医学技术学院教授、博士生导师。2012年入选海外高层次人才支持计划,2015年获得北京市青年拔尖人才计划支持,2020年获得优秀青年科学基金项目支持。长期从事谱学精密仪器研究,实验室以小型化质谱仪器、结构解析质谱新技术为主要特色研究方向。团队突破了离子阱定量准确性等瓶颈问题,研制出国际领先的小型化离子阱质谱仪、疾病智能识别POCT仪器;通过发展迁移电泳原理和非变性结构解析质谱原理,实现了痕量蛋白质三级、四级结构信息的获取,开展了蛋白立体几何结构、内部几何结构、蛋白小分子复合体结构变化的研究。团队发表论文100余篇,获得2017年中国分析测试协会科学技术奖一等奖;2017年国家科学技术进步奖二等奖;2020年中国仪器仪表学会科学技术进步奖一等奖。参与了航天小型质谱仪、防化质谱仪的研发工作,部分研究成果实现了产业转化,开始服务于社会。 教育培训经历 2005-2009,美国普渡大学, 博士 2003-2005,新加坡国立大学,硕士 1999-2003,中国科学技术大学,学士 工作经历 2012年至今,北京理工大学,生命学院,教授 2010-2012,美国普渡大学,生物医学工程,博士后 所获奖励/荣誉 全国高校教师教学创新大赛,二等奖(1/3),2021 国家自然科学基金委,优秀青年科学基金,2020 中国分析测试协会科学技术奖一等奖(1/8),“微型离子阱质谱关键技术研发及应用”,2017 国家科技进步二等奖,(6/9),“超痕量物质精密测量关键技术及应用”,2017 中国仪器仪表学会科学技术进步奖一等奖(11/15),“生物质谱关键技术创新与应用”,2020 北京市青年拔尖人才,2015 海外高层次人才(青年),中组部,2012 北京理工大学杰出中青年教师,北京理工大学,2011

研究领域

POCT智能检测仪器;质谱仪器与分析;结构蛋白组学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Wenjing Zhang, Jie Hong, Lei Yang, Zuqiang Xu, Yu Xiang and Wei Xu*, “Resolving the Geometric Structure of Trastuzumab by Mobility Capillary Electrophoresis and Native Mass Spectrometry”, Chinese Chemical Letter, 2023, accepted. Jian Zhang, Qingce Zang, Wei Xu*, Fei Tang*, “Rapid imaging of unsaturated lipids at isomer level using photoepoxidation”, Talanta, 2023, 261, 124643. Jian Zhang, Zesen Zhang, Ting Jiang, Zhenyu Zhang, Wenjing Zhang, and Wei Xu*, “Rapidly Identifying and Quantifying of Unsaturated Lipids with Carbon-Carbon Double Bond Isomers by Photoepoxidation”, Talanta, 2023, 260, 124575. Yanzuo Jiang, Di Huang, Hongjia Zhang, Ting Jiang* and Wei Xu, “Smart Miniature Mass Spectrometer Enabled by Machine Learning”, Analytical Chemistry, 2023, 95, 14, 5976–5984. Qiong Liang, Siyu Liu, Wei Xu*, Yanbing Zhai*, “Capillary-in-capillary Electrospray Ionization (CC-ESI) Source Enabling Convenient Sampling and Quantitative Analysis for Point of Care Testing” Analytical Chemistry, 2023, 95, 4, 2420–2427. Shiyu Du, Wei Xu, Yanbing Zhai*, “Field-gradient-focusing Ion Guide for Enhanced Transfer Efficiency of Low-mass Ions” Analytical Chemistry, 2023, 95, 3, 2079–2086. Lei Yang, Wenjing Zhang, and Wei Xu*, “Efficient protein conformation dynamics characterization enabled by mobility-mass spectrometry”, Analytica Chimica Acta, 2023, 1243, 340800. (Cover story) Hongjia Zhang, Heyuan Jia, Zhiwu Gao, Ting Jiang,* Wei Xu, “Parallel Pseudo-MRM on the Brick Mass Spectrometer for High Throughput Multi-Target Screening”, Talanta, 2023, 252, 123866 Hao Gu, Guoxin Dai, Siyu Liu, Yanbing Zhai, Qian Xu, Hongqiang Wu, Wei Xu*, “A compact liquid chromatography-mass spectrometry instrument for the quantitation of immunosuppressants”, Chinese Chemical Letter, 2023, 34, 4, 107715. Congrui Tan, Jie Hong,* and Wei Xu*, “Ion Bunching in Square-wave Driven Mobility Capillary Electrophoresis-Mass Spectrometry”, Analytical Chemistry, 2022, 94, 13682-13690. Yiling Li, Hongjia Zhang, Baokun Yang, Xiaosong Li* and Wei Xu, “Development of a handheld mass spectrometer driven by the sinusoidal frequency scanning technique”, International Journal of Mass Spectrometry, 481, 116915, 2022. Wenjing Zhang, Yu Xiang, Wei Xu*, “Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry”, Trac Trends in Analytical Chemistry, 157, 116739, 2022. Xiaotong Shen, Wei Xu,* Jin Ouyang, Na Na*, “Fluorescence resonance energy transfer-based nanomaterials for the sensing in biological systems”, Chinese Chemical Letter, 2022, 33(10), 4505-4516. Siyu Liu, Qian Xu, Yiling Li, Wei Xu,* Yanbing Zhai*, “Coupling Handheld Liquid Microjunction-Surface Sampling Probe (hLMJ-SSP) to the Miniature Mass Spectrometer for Automated and In-situ Surface Analysis”, Talanta, 242, 123090, 2022. Wanzhen Han, Shiyu Du, Caowei Tang, Yiling Li, Ting Jiang,* Wei Xu, “Integration of a Liquid-Phase Ion Trap with a Miniature Mass Spectrometer”, Analytica Chimica Acta, 2022, 1193, 339315.

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