个人简介
黄利利,女,中共党员。北京理工大学副教授、博士生导师。主要研究方向为:病原体检测、单病毒标记与实时动态示踪、溶瘤病毒工程化体系的构建与应用。在Acc. Chem. Res., Nano Lett., Anal. Chem., Chem. Comm.等国际著名学术期刊累计发表SCI论文30余篇。
教育培训经历
2012.09 - 2017.07 北京理工大学 化学工程与技术博士
2009.09 - 2012.07 北京理工大学 生物学硕士
2004.09 - 2008.07 内蒙古农业大学 生物工程学士
工作经历
2020.05 - 至今 北京理工大学 医工融合研究院 特别研究员/副教授
2017.06 - 2020.05 北京理工大学 物理学院 博士后
研究领域
课题组充分发挥病毒学、生物学、化学、免疫学、医学等多学科交叉融合创新优势,围绕疾病精准诊断与治疗中的重要科学问题,以病毒为研究对象,开发一系列先进的检测及诊疗技术。具体的研究方向如下:
1)发展病原体高灵敏检测原始创新技术,提高传染病诊断的准确性和及时性
2)建立病毒的荧光标记新方法,并实时动态示踪其侵染过程,为诠释病毒的感染机制和相应药物的研发提供依据
3)构建光/磁成像-光热/免疫治疗等功能集成的溶瘤病毒,实现活体智能诊断与多功能协同治疗的应用
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
L. L. Huang, W. Nie, J. Zhang, H. Y. Xie*. Cell membrane-based biomimetic systems with bioorthogonal functionalities. Acc. Chem. Res., 2020, 53(1): 276-287. (SCI一区 Top)
L. L. Huang, X. Li, J. F. Zhang, Q. R. Zhao, M. J. Zhang, H. Y. Xie*. MnCaCs-biomineralized oncolytic virus for bimodal imaging guided and synergistically enhanced anticancer therapy. Nano lett., 2019, 19(11): 8002-8009. (SCI一区 Top)
L. L. Huang, L. L. Wu, X. Li, K. Liu, D. Zhao, H. Y. Xie*. Labeling and single particle tracking based entry mechanism study of vaccinia virus from the tiantan strain. Anal. Chem., 2018, 90(5): 3452-3459. (SCI一区 Top)
L. L. Huang, K. Liu, Q. Zhang, J. Xu, D. X. Zhao, H. Zhu, H. Y. Xie*. Integrating two efficient and specific bioorthogonal ligation reactions with natural metabolic incorporation in one cell for virus dual labeling. Anal. Chem., 2017, 89(21): 11620-11627. (SCI一区 Top)
L. L. Huang, G. H. Lu, J. Hao, H. Z. Wang, D. L. Yin, H. Y. Xie*. Enveloped virus labeling via both intrinsic biosynthesis and metabolic incorporation of phospholipids in host cells. Anal. Chem., 2013, 85(10): 5263-5270. (SCI一区 Top)
J. Hao#, L. L. Huang#, R. Zhang, H. Z. Wang, H. Y. Xie*. A mild and reliable method to label enveloped virus with QDs by copper-free click chemistry. Anal. Chem., 2012, 84(19): 8364-8370. (并列第一作者SCI一区 Top)
L. L. Huang, P. Zhou, H. Z. Wang, R. Zhang, J. Hao, H. Y Xie*, Z. K. He*. A new stable and reliable method for labeling nucleic acids of fully replicative viruses. Chem. Comm., 2012, 48(18): 2424-2426. (SCI一区 Top)
L. L. Huang, J. Xu, Y. J. Jin, D. X. Zhao, H. Y. Xie*. Ru(II) polypyridyl complex-incorporated and folate-conjugated vehicle for cancer cell imaging and photoinduced inactivation. Analyst, 2016, 141(10): 2948-2954. (SCI二区)
L. L. Huang, H. Y. Xie*. Progress on the labeling and single-particle tracking technologies of viruses. Analyst, 2014, 139(13): 3336-3346. (SCI二区)
L. L. Huang, X. Li, K. Liu, B. Zou, H. Y. Xie*. Engineering oncolytic vaccinia virus with functional peptides through mild and universal strategy. Anal. Bioanal. Chem., 2019, 411(4): 925-933. (SCI三区)
L. L. Huang, Y. J. Jin, D. X. Zhao, C. Yu, J. Hao, H. Y. Xie*. A fast and biocompatible living virus labeling method based on sialic acid-phenylboronic acid recognition system. Anal. Bioanal. Chem., 2014, 406(11): 2687-2693. (SCI三区)
学术兼职
担任Nano Today, Advanced Science, ACS Nano, Biomaterials, Theranostic等杂志审稿人