Barbaric, Ivana - University of Sheffield - Department of Biomedical Science

个人简介

2014 – present: Lecturer, Centre for Stem Cell Biology, Department of Biomedical Sciences, University of Sheffield. 2013 – 2014: Wellcome Trust Discipline Hopping Fellow, Department of Materials Science and Tissue Engineering, University of Sheffield. 2008 – 2013: Post-doctoral Research Associate, Department of Biomedical Science, University of Sheffield. Research Advisor: Professor Peter Andrews. 2006 – 2008: Post-doctoral Research Associate, Department of Biomedical Science, University. Research Advisor: Professor Peter Andrews. 2002 – 2006: Doctor of Philosophy, Department of Pharmacology/MRC Harwell, University of Oxford. Research Advisor: Professor Stephen Brown. 2001 – 2002: Research Assistant, R&D, Pliva Pharmaceuticals, Zagreb, Croatia. 2000 – 2001: Honours student, Max-Planck Institute for Immunobiology, Freiburg, Germany. Research Advisors: Professor Davor Solter and Dr Grace Wei. 1996 – 2001: Bachelor of Science with Distinction and First Class Honours, University of Zagreb, Croatia.

研究领域

My lab focuses on understanding the mechanisms that control pluripotent stem cell self-renewal and commitment to differentiation. In particular, we investigate the molecular basis of aneuploidy in hPSCs and study how such genetic changes may perturb the normal control of stem cell fate and enhance their ability to grow in culture.

近期论文

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Baker D, Hirst AJ, Gokhale PJ, Juarez MA, Williams S, Wheeler M, Bean K, Allison TF, Moore HD, Andrews PW, Barbaric I. Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells. Stem Cell Reports. 2016 Nov 8;7(5):998-1012. doi: 10.1016/j.stemcr.2016.10.003 Barbaric, I., Biga, V., Gokhale, P. J., Jones, M., Stavish, D., Glen, A., Andrews, P. W. (2014). Time-Lapse Analysis of Human Embryonic Stem Cells Reveals Multiple Bottlenecks Restricting Colony Formation and Their Relief upon Culture Adaptation. Stem Cell Reports, 3(1), 142-155.