Smith, Lisa - University of Sheffield - Department of Animal and Plant Sciences

个人简介

Lecturer (2013-present) Department of Animal and Plant Sciences, University of Sheffield, UK Postdoctoral Fellow (2007-2013) Department of Molecular Biology, Max Planck Institute for Developmental Biology, Germany PhD Student (2002-2006) The Sainsbury Laboratory (Norwich), UK BSc Hons (1998-2001) The University of Queensland, Australia

研究领域

One aspect of my research focuses on plant development. I am particularly interested in the contribution of a group of carbohydrate (sugar)-binding proteins to plant development and its regulation by environmental signals. The malectin domain receptor-like kinases detect signals from outside the cell (either coming from other plant cells or from the surrounding environment) and help the cell and the plant develop appropriately according to the wider environment. Research in the lab also includes the developmental roles of another group of malectin domain proteins with a kinesin domain. Kinesins are motor proteins that can move around the cell using the cytoskeleton. They are particularly important in plant cell division where they can restructure the cytoskeleton and shift organelles. I remain interested in other areas of plant molecular biology such as natural variation and transposable elements therefore a third research area in the lab is examining the long-term effects of biotic stress on heritable variations.

近期论文

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Galindo-Trigo S, Gray JE & Smith LM (2016) Conserved roles of CrRLK1L receptor-like kinases in cell expansion and reproduction from algae to angiosperms. Frontiers in Plant Science, 7(AUG2016). View this article in WRRO López Sánchez A, H M Stassen J, Furci L, Smith LM & Ton J (2016) The role of DNA (de)methylation in immune responsiveness of Arabidopsis.. Plant Journal. View this article in WRRO Smith LM, Burbano HA, Wang X, Fitz J, Wang G, Ural-Blimke Y & Weigel D (2015) Rapid divergence and high diversity of miRNAs and miRNA targets in the Camelineae. The Plant Journal, 81(4), 597-610. Koster T, Meyer K, Weinholdt C, Smith LM, Lummer M, Speth C, Grosse I, Weigel D & Staiger D (2014) Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis. Nucleic Acids Research, 42(15), 9925-9936. View this article in WRRO Todesco M, Kim S-T, Chae E, Bomblies K, Zaidem M, Smith LM, Weigel D & Laitinen RAE (2014) Activation of the Arabidopsis thaliana Immune System by Combinations of Common ACD6 Alleles. PLoS Genetics, 10(7). View this article in WRRO Wang X, Weigel D & Smith LM (2013) Transposon variants and their effects on gene expression in Arabidopsis.. PLoS Genet, 9(2), e1003255. View this article in WRRO Smith LM, Hartmann L, Drewe P, Bohnert R, Kahles A, Lanz C & Rätsch G (2012) Multiple insert size paired-end sequencing for deconvolution of complex transcriptomes.. RNA Biol, 9(5), 596-609. Hollister JD, Smith LM, Guo YL, Ott F, Weigel D & Gaut BS (2011) Transposable elements and small RNAs contribute to gene expression divergence between Arabidopsis thaliana and Arabidopsis lyrata. Proceedings of the National Academy of Sciences of the United States of America, 108(6), 2322-2327. View this article in WRRO Smith LM, Bomblies K & Weigel D (2011) Complex evolutionary events at a tandem cluster of Arabidopsis thaliana genes resulting in a single-locus genetic incompatibility.. PLoS Genet, 7(7), e1002164. View this article in WRRO