耿利娜 - 北京理工大学

个人简介

学习经历 2000年-2003年北京大学化学与分子工程学院博士 1995年-1998年北京理工大学大学化工与材料学院硕士 2015年-2016年美国加州大学圣地亚哥分校访学一年工作经历 2005年-至今北京理工大学生命学院 2003年-2005年国家质量检验检疫总局中国合格评定国家认可中心 1998年-2000年国家环境保护部中日友好环境保护中心承担课题作为项目负责人承担国家自然基金（22176013）和国家自然青年基金（20705005）承担国家重大科学仪器设备开发专项研究-课题6（2012YQ040140）作为第二负责人承担国家“十一五”科技支撑计划项目课题（2009BAK59B02）作为主要成员参加了空间生物与医药工程创新团队所开展的多项国家863重大项目、“十一五”科技支撑重大项目等课题研究主要兼职国家实验室和检查机构认可委员会评审员，国家认证机构认可委员会评审员

研究领域

主要研究内容是利用多学科交叉技术建立生物和医学分离，检测分析新技术新方法，以及开展药物筛选等。主要包括：基于微流控芯片和纳米材料技术建立生物和医学分析与检测新技术新型生物电化学传感器、光电化学传感器技术研究新型生物分析检测、生物医学体外诊断和监测技术研究环境和食品微生物快速检测技术研究高效适配体药物筛选技术研究计算机辅助模拟，图像分析辅助分析以及生物信息学研究

近期论文

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Zongliang Quan, Yu Chen, Xiaochao Zhao, Shiyong Yu, Yongrui Li, Yuanqing Xu, Jiandong Xu, Hui Chen, Lina Geng*, Yulin Deng*, Development of High-Resolution Multidimensional Native Protein Microfluidic Chip Electrophoresis Fingerprinting and its Application in the Quick Analysis of Unknown Microorganisms, Journal of Chromatography (Be accepted) Zerong Liao，Jirun Peng, Shi Chen, Pengjie Zhang, Hui Chen, Dongwei Feng, Tuanjie Zhang, Kaida Ye, Yulin Deng, Yuping Dong, Lina Geng*, Sensitive Fluorescent Sensor for the Fuzzy Exosomes in Serum Based on the Exosome Imprinted Polymer Sandwiched with Aggregation Induced Emission，Sensors and Actuators B: Chemical, https://doi.org/10.1016/j.snb.2021.131182 Baichang Li, Dongwei Feng, Yunfei Miao, Xuewang Liang, Le Gu, Hongying Lan, Shimeng Gao, Yaxi Zhang, Yulin Deng, Lina Geng*, The Systemic Characterization of Aptamer Cocktail for Bacterial Detection Studied by Graphene Oxide Based FRET Aptasensor, Journal of Molecular Recognition，https://doi.org/10.1002/jmr.2934. Yongrui Li, Xuefei Lv, Lina Geng, Chunhua Yang, Weiwei Sun, Yulin Deng*, A chip-based scientific payload technology for visual detection of proteins and its application in spaceflight. Acta Astronautica, 2020, 170:601-608. Zerong Liao, Jianfeng Wang, Pengjie Zhang,Yang Zhang,Yunfei Miao, Shimeng Gao, Yulin Deng, Lina Geng*, Recent advances in microfluidic chip integrated electronic biosensors for multiplexed detection, Biosensors and Bioelectronics, 2018,121(15):272-280. Zerong Liao, Yang Zhang, Yongrui Li, Yunfei Miao, Shimeng Gao, Yulin Deng, Lina Geng*, Microfluidic chip coupled with optical biosensors for simultaneous detection of multiple analytes: A review, Biosensors and Bioelectronics, 2019, 126, 697-706. Yi Lu, Shiyong Yu, Fengming Lin, Fankai Lin, Xiaocao Zhao, Liqing Wu, Yunfei Miao, Huanjun Li, Yulin Deng, Lina Geng*, Simultaneouslabel-free screening of G-quadruplex active ligands from natural medicine via amicrofluidic chip electrophoresis-based energy transfer multi-biosensor strategy, Analyst, 2017, 142(22): 4257-4264 Shiyong Yu, Jiandong Xu, Kunjie Huang, Juan Chen, Jinyan Duan, Yuanqing Xu, Hong Qing, Lina Geng*, Yulin Deng*, A novel method to predict protein aggregations using two-dimensional native protein microfluidic chip electrophoresis, Analytical Methods, 2016(8):8306~8313. Alex Ce Zhang, Yi Gu, Yuanyuan Han, Zhe Mei, Yu-Jui Chiu, Lina Geng, Sung Hwan Cho, Yu-Hwa Lo*, Computational cell analysis for label-free detection of cell properties in a microfluidic laminar flow, Analyst, 2016(14): 4142~4150. Fengmin Lin, Shiyong Yu, Le Gu, Xuetao Zhu, Jianshe Wang, Han Zhu, Yi Lu, Yihua Wang, Yulin Deng, Lina Geng*, In situ photo-immobilised pH gradient isoelectric focusing and zone electrophoresis integrated two-dimensional microfluidic chip electrophoresis for protein separation, Microchimica Acta, 2015, 182(13-14): 2321~2328. Fengming Lin, Xiaochao Zhao, Jianshe Wang, Shiyong Yu, Xuefei Lv, Yulin Deng, Lina Geng*, HuaJun Li*, A novel microfluidic chip electrophoresis strategy for simultaneous, label-free, multi-protein detection based on a graphene energy transfer biosensor, Analyst, 2014(139), 2890-2895. Lin Xia, FengMing Lin, Xin Wu, Jianshe Wang, Chuanli Liu, Qi Tang, Shiyong Yu, Kunjie Huang, XuefeiLv, Yulin Deng, Lina Geng*, On-chip protein isoelectric focusing using a photo-immobilized pH gradient, J. Sep. Sci., 2014, 37 (21), 3174–3180. Hou Ni, Chen Yu, Yu Shiyong, QuanZongliang, Zhu Han, Pan Chenhua, Deng Yulin, Geng Lina*, Native Protein Separation by Isoelectric Focusing and Blue Gel Electrophoresis-Coupled Two-dimensional Microfluidic Chip Electrophoresis, Chromatographia, 2014(77) 1339-1346. Xin Wu, Qi Tang, Chuanli Liu, Qin Li, Yuanyuan Guo, Yanlian Yang, XuefeiLv, Lina Geng*, Yulin Deng*，Protein photoimmobilizations on the surface of quartz glass simply mediated by benzophenon，Appli. Surf. Sci., 257 (2011) 7415-7421. 廖泽荣, 李永瑞, 古乐，雷润宏，苗云飞，蓝鸿颖，邓玉林，耿利娜*，基于微流控芯片的细胞外囊泡分离技术研究进展, 色谱, 2019, 37(04):16-20. 褚平平, 耿利娜, 杨春华，李晓琼，邓玉林. 一种适用于小型毛细管电泳装置的紧凑型荧光检测器的研制, 生命科学仪器, 2019. 叶凯达，杨戍，王鑫宇，韩天骄，张朋杰，孙立权，林凡凯，耿利娜*，罗爱芹*，邓玉林*，结合适配体技术的磁性粒子表面蛋白分子印迹材料研制，北京理工大学学报，2017，37(Supple.1):19-22.