李玉娟 - 北京理工大学

个人简介

2014,9-2015,4：美国耶鲁大学访问学者 2012,5-2013,5：英国莱斯特大学访问学者 2005,4-至今: 北京理工大学生命学院空间生物与医学工程研究所 2003,7-2005,3: 日本新泻药科大学生命科学部博士后 2000,7-2003,6: 沈阳药科大学，药物分析学博士社会兼职中国药学会高级会员、中国药理学会会员、中国化学会会员。任国际刊物Phytomedicine、Journal of Pharmaceutical and Bioanalytical Analysis等杂志审稿专家承担课题国家自然科学基金面上项目（81973572，课题负责人，进行中）航天军需重大专项（AWS16J018，课题负责人，进行中）国家重大科学仪器设备开发专项（2012YQ12004410，课题负责人，已结题）国家自然科学基金面上项目（81573693，课题负责人，已结题）国家自然科学基金青年基金项目（81202996，课题负责人，已结题）还曾主持国家重大科学基础研究计划、载人航天领域预先研究项目等多项科研项目。作为主要参加者曾参与完成国家重大科学仪器专项、863重大专项等项目。已经在国内外药学重要学术刊物上发表学术论文近百余篇

研究领域

基于核酸适配体分子探针的中药药效物质基础研究航天失重条件下神经及肠道损伤的中医药防护机制研究航天失重条件下中药药物动力学变化机制研究（肠吸收、肝代谢、血脑屏障转运等）

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Ranran Yan, Huayan Liu, Fang Lv, Yulin Deng, Yujuan Li*, Rac1/Wave2/Arp3 Pathway Mediates Rat Blood-Brain Barrier Dysfunction under Simulated Microgravity Based on Proteomics Strategy，Int J Mol Sci, 2021，DOI: 10.3390/ijms22105165. Yujuan Li*, Lili Huang, Javed Iqbal, Yulin Deng, Study of P-glycoprotein interaction proteins in rat brain under simulated microgravity-Labeled free comparative proteomics approach，Space: Science & Technology, 20210201. Shibo Wang, Rui Wang, George Q. Li, Jun-Lae Cho, Yulin Deng, Yujuan Li*, Simulated microgravity effect could increase the intestinal epithelium permeability by enhancement of myosin light chain phosphorylation: a proteomic approach, Journal of Proteomics, 2020, DOI: 10.1016/j.jprot.2020.104001. Bo Chen, George Q Li, Yongzhi Li, Jun Lae Cho, Jiaping Wang, Jianyi Gao, Yulin Deng，Yujuan Li*，Proteomic changes related to energy metabolism and oxidative stress in rat exposed to simulated microgravity, Acta Astronautica, 2020, DOI: 10.1016/j.actaastro.2020.02.007. Huayan Liu, Jingjing Guo, Yujuan Li*, Yushi Zhang, Jiaping Wang, Jianyi Gao, Yulin Deng, Yongzhi Li*. Investigation on Intestinal Proteins and Drug Metabolizing Enzymes in Simulated Microgravity Rats by a Proteomics method, Molecules,2020, DOI:10.3390/molecules 25194391. CHEN Bo, ZHANG Yushi, LI George, CHO Jun-Lae, DENG Yulin*, LI Yujuan*, The Impacts of Simulated Microgravity on Rat Brain Depended on Durations and Regions, Biomedical and Environmental Sciences，Biomed Environ Sci, 2019; 32(5): 323. Bo Chen, Jingjing Guo, Shibo Wang, Liting Kang, Yulin Deng*, Yujuan Li*, Simulated Microgravity Disrupted the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats, Front Pharmacol, 2018,DOI: 10.3389/fphar.2018.01130.