朱旺升 - 中国农业大学 - 植物保护学院

个人简介

工作经历 2019.10-至今中国农业大学教授 2014.06-2019.09 Max Planck Institute for Developmental Biology 博士后教育经历 2010.02-2014.05 Monash University (Australia) 博士 2005.07-2008.03 东华大学硕士 2001.09-2005.07 华中农业大学本科社会、学术兼职美国植物微生物互作协会会员 Frontiers in Plant Science 编委 BMC Plant Biology, Developmental Gene and Evolution 期刊审稿人科研项目中国农业大学高层次引进人才启动基金（2019-2025）奖励情况湖北省大学生优秀科研成果一等奖湖北省教育厅（2005）

研究领域

（一）植物细胞死亡信号转导细胞死亡是植物免疫应答中重要生理反应之一，实验室将以植物跨膜免疫蛋白ACD6及其调控蛋白MHAL为研究对象，解析植物细胞死亡的信号转导及分子调控机制，并进一步研究该信号通路在植物抗病中的作用机理。（二）植物抗病的数量调控遗传基础自然植物群体如森林很少发现大面积的病害爆发，这和自然群体中蕴含丰富的遗传多样性有重要关系。在自然群体中，植物抵抗病害主要表现为通过多基因和环境互作控制的数量性状，在和病原菌漫长的共进化过程中，植物维持了持久的疾病抗性。因此，理解自然植物群体在不同环境条件下（营养和温度等）抵抗病害的遗传机制，将帮助设计具有持续抗性的作物提供研究思路和农业决策理论基础。（三）作物重要病害抗性遗传资源挖掘在作物驯化过程中，不同的优势农艺性状会被人工选择而固定在栽培种中，在一定条件下，高疾病抗性品种会被人工驯化；另一方面，高疾病抗性基因也会对产量和其他性状产生影响而被排斥在栽培种中。实验室将通过对玉米栽培种和野生种杂交后代分离群体的病害抗性进行系统分析，通过高通量遗传分析手段鉴定影响玉米病害抗性的数量性状基因座位，为培育具有高抗高产的玉米品种提供遗传资源和理论基础。

近期论文

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Hu B, Wang N, Bi X, Karaaslan ES, Weber AL, Zhu W, Berendzen KW, Liu C*. Plant lamin-like proteins mediate chromatin tethering at the nuclear periphery. Genome Biology. 2019, 20(1):87 Exposito-Alonso M; 500 Genomes Field Experiment Team, Burbano HA, Bossdorf O, Nielsen R, Weigel D*. Natural selection on the Arabidopsis thaliana genome in present and future climates. Nature. 2019, 573(7772):126-129. Méndez-Vigo B, Ausín I, Zhu W, Mollá-Morales A, Balasubramanian S, Alonso-Blanco C*. Genetic interactions and molecular evolution of the duplicated genes ICARUS2 and ICARUS1 help Arabidopsis plants adapt to different ambient temperatures. The Plant Cell, 2019, 31(6): 1222-1237. Wu R, Lucke M, Jang Y, Zhu W, Symeonidi E, Wang C, Fitz J, Xi W, Schwab R, Weigel D*. An efficient CRISPR vector toolbox for obtaining large deletions in Arabidopsis thaliana. Plant Methods 2018, 14:65 Zhu W#, Zaidem M#, Van de Weyer AL, Gutaker RM, Chae E, Kim ST, Bemm F, Li L, Schwab R, Unger F, Beha M, Demar M and Weigel D*. Modulation of ACD6 dependent hyper-immunity by natural alleles of an Arabidopsis thaliana NLR resistance gene. PLoS Genetics, 2018, 14(9):e1007628 Zhu W#, Hu B, Becker C, Do?an ES, Berendzen KW, Weigel D* and Liu C#*. Altered chromatin compaction and histone methylation drive non-additive gene expression in an interspecific Arabidopsis hybrid. Genome Biology. 2017, 18: 157. Grimm DG*, Roqueiro D, Salomé PA, Kleeberger S, Greshake B, Zhu W, Liu C, Lippert C, Stegle O, Sch?lkopf B, Weigel D, Borgwardt KM*. easyGWAS: A Cloud Based Platform for Comparing the Results of Genome-Wide Association Studies. The Plant Cell. 2017, 29(1): 1-9. Exposito-Alonso M, … Zhu W, … Weigel D. A rainfall-manipulation experiment with 517 Arabidopsis thaliana accessions. bioRxiv, 2017, https://doi.org/10.1101/186767. Sanchez-Bermejo E#, Zhu W#, Tasset C, Eimer H, Sureshkumar S, Singh R, Sundaramoorthi V, Colling L, Balasubramanian S*. Genetic architecture of natural variation in thermal response of Arabidopsis thaliana. Plant Physiology. 2015, 169: 647-59. Zhu W#, Ausin I#, Seleznev A, Méndez-Vigo B, Picó FX, Sureshkumar S, Sundaramoorthi V, Bulach D, Powell D, Seemann T, Alonso-Blanco C*, Balasubramanian S*. Natural variation identifies ICARUS1, a universal gene required for cell proliferation and growth at high temperatures in Arabidopsis thaliana. PLoS Genetics. 2015, 11(5): e1005085. Zhu W#, Fan Z#, Zhang C, Guo Z, Zhao Y, Zhou Y, Li K, Xing Z, Chen G, Liang Y, Jin L, Xiao J*. A dominant X-linked QTL regulating pubertal timing in mice found by whole genome scanning in reciprocal pedigrees and modified interval specific congenic strains analysis. PLoS One. 2008, 3(8): e3021. Zhou Y, Zhu W, Guo Z, Zhao Y, Song Z, Xiao J*. Effects of maternal nuclear genome on the timing of puberty in mice offspring. Journal of Endocrinology. 2007, 193(3): 405?412. Zhu W, Xu J, Hua Y, Li Z*. Genomic analysis of intergeneric hybrids between Brassica carinata and Orychophragmus violaceus by using in situ hybridization. Acta Botanica Boreali-occidentalia Sinica (Chinese). 2005, 25(4): 662-667.