个人简介
Career History
2008 - present: Professor, Dept of Molecular Biology and Biotechnology, University of Sheffield
2008: Reader, Dept of Molecular Biology and Biotechnology, University of Sheffield
2003 - 2007: Senior Lecturer, Dept of Molecular Biology and Biotechnology, University of Sheffield
1999 - 2003: Lecturer Dept. of Biomolecular Sciences, UMIST
1996 - 1999: Weir Junior Research Fellow, University College Oxford
1995 - 1999: Wellcome Trust Career Development Fellow, Biochemistry Dept, Oxford University
1991 - 1995: Post-doctoral fellow, Biochemistry Department, University College London
1987 - 1991: PhD student, Biochemistry Department, University College London
1984 - 1987: Degree in Cell and Molecular Biology, Biophysics Department, King's College London
研究领域
The regulation of gene expression in mammals, focusing on mRNA; mRNA export from the nucleus to the cytoplasm; mechanisms of RNA interference. Large scale sequencing and gene function analysis in vertebrates.
近期论文
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Heath CG, Viphakone N & Wilson SA (2016) The role of TREX in gene expression and disease.. Biochemical Journal, 473(19), 2911-2935. View this article in WRRO
Viphakone N, Cumberbatch MG, Livingstone MJ, Heath PR, Dickman MJ, Catto JW & Wilson SA (2015) Luzp4 defines a new mRNA export pathway in cancer cells. Nucleic Acids Research, 43(4), 2353-2366. View this article in WRRO
Viphakone N, Cumberbatch MG, Livingstone MJ, Heath PR, Dickman MJ, Catto JW & Wilson SA (2015) Luzp4 defines a new mRNA export pathway in cancer cells. Nucleic Acids Research, 43(4), 2353-2366. View this article in WRRO
Snijders AP, Hautbergue GM, Bloom A, Williamson JC, Minshull TC, Phillips HL, Mihaylov SR, Gjerde DT, Hornby DP, Wilson SA, Hurd PJ & Dickman MJ (2015) Arginine methylation and citrullination of splicing factor proline- and glutamine-rich (SFPQ/PSF) regulates its association with mRNA. RNA, 21(3), 347-359. View this article in WRRO
Caballero-Lima D, Hautbergue GM, Wilson SA & Sudbery PE (2014) In C andida albicans hyphae, Sec2p is physically associated with SEC2 mRNA on secretory vesicles. Molecular Microbiology, 94(4), 828-842. View this article in WRRO
Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J, Hautbergue GM & Shaw PJ (2014) Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.. Brain, 137(Pt 7), 2040-2051. View this article in WRRO
Tunnicliffe RB, Hautbergue GM, Wilson SA, Kalra P & Golovanov AP (2014) Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF.. PLoS Pathog, 10(2), e1003907. View this article in WRRO
Viphakone N, Hautbergue GM, Walsh M, Chang C-T, Holland A, Folco EG, Reed R & Wilson SA (2013) Erratum: TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export. Nature Communications, 4.
Teng IF & Wilson SA (2013) Mapping interactions between mRNA export factors in living cells.. PLoS One, 8(6), e67676.
Chang CT, Hautbergue GM, Walsh MJ, Viphakone N, van Dijk TB, Philipsen S & Wilson SA (2013) Chtop is a component of the dynamic TREX mRNA export complex.. EMBO J, 32(3), 473-486.