Sudbery, Ian - University of Sheffield - Department of Molecular Biology and Biotechnology

个人简介

2014 - present: Lecturer in Bioinformatics, Department of Molecular Biology and Biotechnology, The University of Sheffield 2011 - 2014: CGAT Fellow, MRC Functional Genomics Unit at the University of Oxford 2009 - 2011: Postdoctoral Research Fellow, Department of Systems Biology, Harvard Medical School 2007 - 2008: Postdoctoral Research Assistant, Wellcome Trust Sanger Institute 2003 - 2007: PhD in Functional Genomics, The Wellcome Trust Sanger Institute/University of Cambridge

研究领域

Understanding how eukaryotes integrate information and regulate gene expression using computational and functional genomics tools, for example miRNAs in transcript destabilisation and translational inhibition.

近期论文

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Greig JA, Sudbery IM, Richardson JP, Naglik JR, Wang Y & Sudbery PE (2015) Cell Cycle-Independent Phospho-Regulation of Fkh2 during Hyphal Growth Regulates Candida albicans Pathogenesis. PLOS Pathogens, 11(1), e1004630-e1004630. View this article in WRRO Rajan P, Stockley J, Sudbery IM, Fleming JT, Hedley A, Kalna G, Sims D, Ponting CP, Heger A, Robson CN, McMenemin RM, Pedley ID & Leung HY (2014) Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer. BMC Cancer, 14(1). Rajan P, Sudbery IM, Villasevil MEM, Mui E, Fleming J, Davis M, Ahmad I, Edwards J, Sansom OJ, Sims D, Ponting CP, Heger A, McMenemin RM, Pedley ID & Leung HY (2014) Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy. European Urology, 66(1), 32-39. Sims D, Ilott NE, Sansom SN, Sudbery IM, Johnson JS, Fawcett KA, Berlanga-Taylor AJ, Luna-Valero S, Ponting CP & Heger A (2014) CGAT: computational genomics analysis toolkit. Bioinformatics, 30(9), 1290-1291. Sims D, Sudbery I, Ilott NE, Heger A & Ponting CP (2014) Sequencing depth and coverage: key considerations in genomic analyses. Nature Reviews Genetics, 15(2), 121-132. Huang Z-X, Zhao P, Zeng G-S, Wang Y-M, Sudbery I & Wang Y (2014) Phosphoregulation of Nap1 Plays a Role in Septin Ring Dynamics and Morphogenesis in Candida albicans. mBio, 5(1), e00915-13-e00915-13. Farcas AM, Blackledge NP, Sudbery I, Long HK, McGouran JF, Rose NR, Lee S, Sims D, Cerase A, Sheahan TW, Koseki H, Brockdorff N, Ponting CP, Kessler BM & Klose RJ (2012) KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands. eLife, 1. Daelemans C, Ritchie ME, Smits G, Abu-Amero S, Sudbery IM, Forrest MS, Campino S, Clark TG, Stanier P, Kwiatkowski D, Deloukas P, Dermitzakis ET, Tavaré S, Moore GE & Dunham I (2010) High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta. BMC Genetics, 11(1), 25-25. Sudbery I, Enright AJ, Fraser AG & Dunham I (2010) Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis. BMC Genomics, 11(1), 175-175. Turner DJ, Keane TM, Sudbery I & Adams DJ (2009) Next-generation sequencing of vertebrate experimental organisms. Mammalian Genome, 20(6), 327-338.