Partridge, Lynda - University of Sheffield - Department of Molecular Biology and Biotechnology

个人简介

Career History 1998 - present: Senior Lecturer, Dept. Molecular Biology & Biotechnology, University of Sheffield 2009 - present: Scientific Director, Bioserv UK Ltd. 1988 - 1998: Lecturer, Dept. Molecular Biology & Biotechnology, University of Sheffield 1982 - 1988: Post-doctoral research assistant, Dept. Biochemistry, University of Sheffield 1979 - 1982: PhD student, Dept Immunology, University of Birmingham

研究领域

Human leucocyte antigens, specifically the structure and function of tetraspanins, a conserved family of mammalian transmembrane proteins. Role of tetraspanins in bacterial infection. Monoclonal antibody technology for research and medicine.

近期论文

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Ventress JK, Partridge LJ, Cozens D, Read RC, MacNeil S & Monk PN (2016) Peptides from Tetraspanin CD9 Are Potent Inhibitors of Staphylococcus Aureus Adherence to Keratinocytes. PLoS One. View this article in WRRO Rust A, Hassan HHA, Sedelnikova S, Niranjan D, Hautbergue G, Abbas SA, Partridge L, Rice D, Binz T & Davletov B (2015) Two complementary approaches for intracellular delivery of exogenous enzymes. Scientific Reports, 5, 12444-12444. View this article in WRRO Hulme RS, Higginbottom A, Palmer J, Partridge LJ & Monk PN (2014) Distinct Regions of the Large Extracellular Domain of Tetraspanin CD9 Are Involved in the Control of Human Multinucleated Giant Cell Formation. PLoS ONE, 9(12), e116289-e116289. View this article in WRRO Monk PN & Partridge LJ (2012) Tetraspanins: gateways for infection.. Infect Disord Drug Targets, 12(1), 4-17. Cruz-Migoni A, Hautbergue GM, Artymiuk PJ, Baker PJ, Bokori-Brown M, Chang CT, Dickman MJ, Essex-Lopresti A, Harding SV, Mahadi NM, Marshall LE, Mobbs GW, Mohamed R, Nathan S, Ngugi SA, Ong C, Ooi WF, Partridge LJ, Phillips HL, Raih MF, Ruzheinikov S, Sarkar-Tyson M, Sedelnikova SE, Smither SJ, Tan P, Titball RW, Wilson SA & Rice DW (2011) A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A.. Science, 334(6057), 821-824. Green LR, Monk PN, Partridge LJ, Morris P, Gorringe AR & Read RC (2011) Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells.. Infect Immun, 79(6), 2241-2249. View this article in WRRO Fanaei M, Monk PN & Partridge LJ (2011) The role of tetraspanins in fusion.. Biochem Soc Trans, 39(2), 524-528. Trikić MZ, Monk P, Roehl H & Partridge LJ (2011) Regulation of zebrafish hatching by tetraspanin cd63.. PLoS One, 6(5), e19683. View this article in WRRO Parthasarathy V, Martin F, Higginbottom A, Murray H, Moseley GW, Read RC, Mal G, Hulme R, Monk PN & Partridge LJ (2009) Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells.. Immunology, 127(2), 237-248.