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个人简介

Career History 2004 - present: Professor of Microbiology, University of Sheffield 2000 - 2004: Reader in Microbiology, University of Sheffield 1995 - 2000: BBSRC Advanced Fellow, University of Sheffield 1989 - 1995: BBSRC PDRA, University of Sheffield 1984 - 1989: SERC PDRA, University of Warwick 1980 - 1983: SERC Research Assistant, University of Hull

研究领域

The regulation of bacterial transcription in response to changes in oxygen availability, and to oxidative and nitrosative stress; iron-sulphur proteins as regulators; role of CRP-FNR family transcription factors in bacterial stress responses.

近期论文

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Ibrahim SA, Crack JC, Rolfe MD, Acuña JMB-D, Thomson AJ, Le Brun NE, Schobert M, Stapleton MR & Green J (2015) Three Pseudomonas putida FNR Family Proteins with Different Sensitivities to O 2. Journal of Biological Chemistry, 290(27), 16812-16823. View this article in WRRO Denby KJ, Rolfe MD, Crick E, Sanguinetti G, Poole RK & Green J (2015) Adaptation of anaerobic cultures of Escherichia coliK-12 in response to environmental trimethylamine-N-oxide. Environmental Microbiology, 17(7), 2477-2491. View this article in WRRO Crack JC, Green J, Thomson AJ & Brun NEL (2014) Iron–Sulfur Clusters as Biological Sensors: The Chemistry of Reactions with Molecular Oxygen and Nitric Oxide. Accounts of Chemical Research, 47(10), 3196-3205. Bai H, Rolfe MD, Jia W, Coakley S, Poole RK, Green J & Holcombe M (2014) Agent-based modeling of oxygen-responsive transcription factors in Escherichia coli.. PLoS Comput Biol, 10(4), e1003595. View this article in WRRO Crack JC, Stapleton MR, Green J, Thomson AJ & Le Brun NE (2013) Mechanism of [4Fe-4S](Cys)4 cluster nitrosylation is conserved among NO-responsive regulators. Journal of Biological Chemistry, 288(16), 11492-11502. Zhang B, Crack JC, Subramanian S, Green J, Thomson AJ, Le Brun NE & Johnson MK (2012) Reversible cycling between cysteine persulfide-ligated [2Fe-2S] and cysteine-ligated [4Fe-4S] clusters in the FNR regulatory protein. Proceedings of the National Academy of Sciences of the United States of America, 109(39), 15734-15739. Smith LJ, Stapleton MR, Buxton RS & Green J (2012) Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1.. PLoS One, 7(7), e40407. Rolfe MD, Ter Beek A, Graham AI, Trotter EW, Asif HM, Sanguinetti G, de Mattos JT, Poole RK & Green J (2011) Transcript profiling and inference of Escherichia coli K-12 ArcA activity across the range of physiologically relevant oxygen concentrations.. J Biol Chem, 286(12), 10147-10154.

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