个人简介
2022.07-至今：中国农业大学，优秀人才引进，副教授
2018.04-2022.03：美国普渡大学，博士后
2014.08-2021.03：中国医学科学院基础医学研究所，助理研究员
2009.09-2014.07：中国农业大学，理学博士
2005.09-2009.07：河北科技师范学院，理学学士
课题项目
北京自然科学基金青年项目（2016-2017）, 2016035, lncRNA在细胞凋亡信号传递中作用机制的研究，8万，主持
北京协和医学院“协和青年科研基金”（2017-2018）, 3332017056, Lnc-HpGC参与幽门螺杆菌致基因组不稳定诱发胃癌的机制研究，15万，主持
国家自然科学基金面上项目（2017-2020）, 81673642, 基于Wnt/β-catenin信号通路探讨香加皮杠柳苷逆转食管癌细胞对TRAIL的耐药作用及机制研究，57万，合作单位负责人
国家自然科学基金面上项目（2016-2019）, 81572755, lncRNA参与幽门螺杆菌所致慢性胃炎恶性转化的机制研究，55万，参与
近期论文
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Sun J, Wu G, Pastor F, Rahman N, Wang WH, Zhang Z, Merle P, Hui L, Salvetti A, Durantel D, Yang D, Andrisani O*. RNA helicase DDX5 enables STAT1 mRNA translation and interferon signaling in hepatitis B virus replicating hepatocytes. Gut. 71(5):991-1005,2022.
Rahman N#, Sun J#, Li Z#, Pattnaik A, Mohallem R, Wang M, Kazemian M, Aryal U, Andrisani O*. The cytoplasmic LSm1-7 and nuclear LSm2-8 complexes exert opposite effects on Hepatitis B virus biosynthesis and infterferon response. Front Immunol. 2022. Accepted.
Sun J#, Zhang S#, Shi B, Zheng D, Shi J*. Transcriptome identified lncRNAs associated with renal fibrosis in UUO rat model. Front Physiol. 8:658,2017.
Sun J, Wang J, Wang S, Yuan D, Li Z, Yi B, Hou Q, Mao Y, Liu W*. MicroRNA miR-320a and miR-140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor. Virol J. 11(1):210,2014.
Sun J, Wang J, Wang S, Yuan D, Birame BM, Li Z, Yi B, Liu W*. MicroRNA profile analysis of a feline kidney cell line before and after infection with mink enteritis virus. Gene. 539: 224-229,2014.
Sun J, Wang J, Yuan D, Wang S, Li Z, Yi B, Mao Y, Hou Q, Liu W*. Cellular microRNA miR-181b inhibits replication of mink enteritis virus by repression of non-structural protein 1 translation. PLoS One. 8 (12): e81515,2013.
Ma S, Sun J, Guo Y, Zhang P, Liu Y, Zheng D, Shi J*. Combination of AAV-TRAIL with miR-221-Zip therapeutic strategy overcomes the resistance to TRAIL induced apoptosis in liver cancer. Theranostics. 7(13):3228-3242,2017.
Han T, Jing X, Bao J, Zhao L, Zhang A, Miao R, Guo H, Zhou B, Zhang S, Sun J, Shi J*. H. pylori infection alters repair of DNA double-strand breaks via SNHG17. J. Clin. Invest. 130(7):3901-3918,2020
Mani SKK, Yan B, Cui Z, Sun J, Utturkar S, Foca A, Fares N, Duantel D, Lanman N, Merle P, Kazemian M, Andrisani O*. Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma. Theranostics. 10(24):10957-10972,2020.
Zhao L, Han T, Li Y, Sun J, Zhang S, Liu Y, Shan B, Zheng D, Shi J*. The lncRNA SNHG5/miR-32 axis regulates gastric cancer cell proliferation and migration by targeting KLF4. FASEB J. 31(3):893-903,2017.
Li Z, Wang J, Yuan D, Wang S, Sun J, Yi B, Hou Q, Mao Y, Liu W*. A recombinant canine distemper virus expressing a modified rabies virus glycoprotein induces immune responses in mice. Virus Genes. 50(3):434-441,2015.
Yuan D, Wang J, Li Z, Mao Y, Sun J, Xi J, Wang S, Hou Q, Yi B, Liu W*. Establishment of a rescue system for an autonomous Parvovirus mink enteritis virus. Virus Res. 183:1-5,2014.
Wang S, Zhang P, He F, Wang JG, Sun J, Li ZL, Yi B, Xi J, Mao YP, Hou Q, Yuan DL, Zhang ZD, Liu WQ. Combination of specific single chain antibody variable fragment and siRNA has a synergistic inhibitory effect on the propagation of avian influenza virus H5N1 in chicken cells. Virol J. 11:208,2014.
Yi B, Wang J, Wang S, Yuan D, Sun J, Li Z, Mao Y, Hou Q, Liu W. Overexpression of Banna mini-pig inbred line fatty acid binding protein 3 promotes adipogenesis in 3T3-L1 preadipocytes. Cell Biol Int. 38(8):918-923,2014.
Birame BM, Wang J, Yu F, Sun J, Li Z, Liu W*. Potentiation of apoptin-induced apoptosis by cecropin B-Like antibacterial peptide ABPs1 in human HeLa cervical cancer cell lines is associated with membrane pore formation and caspase-3 activation. J Microbiol Biotechnol. 24(6):756–764,2014.
Birame BM, Wang J, Yu F, Wang S, Yuan D, Sun J, Li Z, Yi B, Liu W*. Co-expression of apoptin (VP3) and antibacterial peptide cecropin B mutant (ABPS1) genes induce higher rate of apoptosis in HepG2 and A375 cell lines. Afr J Biotechnol. 11(49):10981-10988,2012.
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