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个人简介

教育经历 2007年9月-2014年6月,中国农业大学,食品科学与营养工程学院,食品科学专业,获得工学博士学位 2003年9月-2007年6月,中国农业大学,食品科学与营养工程学院,生物工程专业,获得工学学士学位 工作经历 2019年6月-至今,中国农业大学,食品科学与营养工程学院,副教授 2019年1月-2019年5月,北京资源亚太饲料科技有限公司,技术经理 2015年11月-2017年12月,美国加州大学戴维斯分校,博士后 2014年12月-2018年12月,中国农业大学,园艺学院,博士后 获得奖励 2015年,获得“博士后国际交流计划(20150027)”资助 2013年,获得“博士研究生国家奖学金” 2011年,获得“爱普科研奖学金”

研究领域

益生菌肠道适应机制(酸和胆盐胁迫的耐受)的研究 益生菌促进肠道健康的分子机制研究 乳酸菌次级代谢产物的功能研究及益生产品的开发

近期论文

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ZHAI, Z., TORRES-FUENTES, C., HEENEY, D. D., & MARCO, M. L. (2019). Synergy between probiotic Lactobacillus casei and milk to maintain barrier integrity of intestinal epithelial cells. J AgriFood Chem,67(7), 1955-1962. ZHAI, Z., WANG, J., HUANG, B., &YIN, S. (2019).Low-fat yogurt alleviates the pro-inflammatory cytokine IL-1β induced intestinal epithelial barrier dysfunction. J Dairy Sci, 102(2), 976-984. ZHAI, Z., YANG, Y., WANG, J.,WANG, G., REN, F., & HAO, Y. (2019).Complete genome sequencing of Lactobacillus plantarum CAUH2 reveals a novel plasmid pCAUH203 associated with oxidative stress tolerance.3 Biotech, 9:116. ZHAI, Z., AN, H., WANG, G., LUO, Y., & HAO, Y. (2015). Functional role of pyruvate kinase from Lactobacillus bulgaricus in acid tolerance and identification of its transcription factor by bacterial one-hybrid. Sci Rep-UK, 5. ZHAI, Z., DOUILLARD, F.P., AN, H., WANG, G., GUO, X., LUO, Y., & HAO, Y. (2014) Proteomic characterization of the acid tolerance response in Lactobacillus delbrueckii subsp. bulgaricus?CAUH1 and functional identification of a novel acid stress-related transcriptional regulator Ldb0677. Environ Microbiol,16(6), 1524-1537. ZHAI, Z.1, HAO, Y.1, YIN, S., LUAN, C., ZHANG, L., ZHAO, L., CHEN, D., WANG, O. & LUO, Y. (2009) Characterization of a novel rolling-circle replication plasmid pYSI8 from Lactobacillus sakei YSI8. Plasmid, 62, 30-34. (1These authors contributed equally to this work). XU, Q.1, ZHAI, Z.1, AN, H., YANG, Y., YIN, J.,WANG, G.,REN, F. & HAO, Y. (2019).The MarR family regulator BmrR is involved in bile tolerance of Bifidobacterium longum BBMN68 via controlling the expression of an ABC-transporter. Appl Environ Microbiol, 85(3), e02453-18.(1These authors contributed equally to this work). HEENEY, DD., ZHAI, Z., BENDIKS, Z., BAROUEI, J., MARTINIC, A., SLUPSKY, C., MARCO, ML. (2018).Lactobacillus plantarum bacteriocin is associated with intestinal and systemic improvements in diet-induced obese mice and maintains epithelial barrier integrity in vitro. GutMicrobes.10(3):382-397. ZHOU, P.,ZHAI, Z., XIONG, Y., MA, X. & HAO, Y.(2018).Characterization of a cryptic Rolling-Circle Replication Plasmid pMK8 fromEnterococcus durans 1-8. Curr Microbiol.1-8. MA, X., WANG, G., ZHAI, Z., ZHOU, P., & HAO, Y. (2018). Global transcriptomic analysis and function identification of malolactic enzyme pathway of Lactobacillus paracasei L9 in response to bile stress. Front Microbiol, 9.

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