吴森 - 中国农业大学

个人简介

学习与工作经历 1988-1993 北京农业大学动物医学院，本科 1993-1998卫生部北京生物制品研究所，助理工程师加拿大University of Saskatchewan，读硕士研究生 1999-2006 美国 University of Utah，博士学位，导师 Mario Capecchi 美国 HHMI/University of Utah，博士后, 导师 Mario Capecchi 2010-至今中国农业大学生物学院，教授主讲课程《动物高级生理学与分子生物学》

研究领域

动物遗传工程及干细胞

近期论文

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Kurokawa S, Eriksson S, Rose KL, Wu S, Motley AK, Hill S, Winfrey VP, McDonald WH, Capecchi MR, Atkins JF, Arnér ES, Hill KE, Burk RF. Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1. Free Radic Biol Med. 69C:67-76. 2014 Hill KE, Wu S, Motley AK, Stevenson TD, Winfrey VP, Capecchi MR, Atkins JF, Burk RF. Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis. J Biol Chem. 287(48):40414-24. 2012 Hill KE, Wu S, Motley AK, Stevenson TD, Winfrey VP, Capecchi MR, Atkins JF, Burk RF. Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis.J Biol Chem. 2012 Nov 23;287(48):40414-24. doi: 10.1074/jbc.M112.421404. Epub 2012 Oct 4.PMID: 23038251 Chen SK, Tvrdik P, Peden E, Cho S, Wu S, Spangrude G, Capecchi MR.Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell. 2010May 28;141(5):775-85. PubMed PMID: 20510925; PubMed Central PMCID: PMC2894573. Xue H, Wu S, Papadeas ST, Spusta S, Swistowska AM, MacArthur CC, Mattson MP,Maragakis NJ, Capecchi MR, Rao MS, Zeng X, Liu Y. A targeted neuroglial reporterline generated by homologous recombination in human embryonic stem cells. StemCells. 2009 Aug;27(8):1836-46. PubMed PMID: 19544414; PubMed Central PMCID:PMC2741170. Ying G, Wu S, Hou R, Huang W, Capecchi MR, Wu Q. The protocadherin gene Celsr3is required for interneuron migration in the mouse forebrain. Mol Cell Biol. 2009Jun;29(11):3045-61. Epub 2009 Mar 30. PubMed PMID: 19332558; PubMed CentralPMCID: PMC2682005. Jia Q, McDill BW, Sankarapandian B, Wu S, Liapis H, Holzman LB, Capecchi MR,Miner JH, Chen F. Ablation of developing podocytes disrupts cellular interactionsand nephrogenesis both inside and outside the glomerulus. Am J Physiol RenalPhysiol. 2008 Dec;295(6):F1790-8. Epub 2008 Oct 8. PubMed PMID: 18842818; PubMed Central PMCID: PMC2604822. Wu S, Ying G, Wu Q, Capecchi MR. A protocol for constructing gene targetingvectors: generating knockout mice for the cadherin family and beyond. Nat Protoc.2008;3(6):1056-76. PubMed PMID: 18546598. Wu S, Ying G, Wu Q, Capecchi MR. Toward simpler and faster genome-wide mutagenesis in mice. Nat Genet. 2007 Jul;39(7):922-30. Epub 2007 Jun 17. PubMedPMID: 17572674. Wu S, Wu Y, Capecchi MR. Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development. 2006 Feb;133(4):581-90. Epub2006 Jan 11. PubMed PMID: 16407399. Gaufo GO, Wu S, Capecchi MR. Contribution of Hox genes to the diversity of thehindbrain sensory system. Development. 2004 Mar;131(6):1259-66. Epub 2004 Feb 11.PubMed PMID: 14960494.