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个人简介

张焱 博士,副教授,研究生导师。2014年获得中国农业大学理学博士学位,2017年以“优秀人才”引进中国农业大学,任生物学院副教授。 学习与工作经历 2017年9月-至今:副教授 中国农业大学 2014年7月-2017年7月:博士后 清华大学 2012年11月-2013年6月:访问学者 加拿大哥伦比亚大学 2009年9月-2014年6月:博士 中国农业大学 2004年9月-2009年6月:学士 中国农业大学

研究领域

以小鼠为主要模式动物,构建卵巢发育各个时期的细胞生物学活体观察体系,结合生理学、细胞生物学、生物化学和分子生物学等主要手段,探索雌性卵巢的发育过程中重要的生物学事件的调控机制

近期论文

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Zhang Yan1, Wang Y1, Feng Xa, Zhang S, Xu X, Li L, Niu S, Bo Y, Wang C, Li Z, Xia G, Zhang H*. (2021) Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice. Nature Communications 12:2523. Zhang J, Yan L, Wang Y, Zhang S, Xu X, Dai Y, Zhao S, Li Z, Zhang Yan, Xia G, Qin Y, Zhang H*.(2020) In vivo and in vitro activation of dormant primordial follicles by EGF treatment in mouse and human. Clin Transl Med 2020; 10:e182. 张焱1,张华*. (2020)哺乳动物卵巢卵泡发育调控机制研究进展,生理学报,.72(01) Yan H, Zhang J, Wen J, Wang Y, Niu W, Teng Z, Zhao T, Dai Y, Zhang Yan, Wang C, Qin Y, Xia G, Zhang H. (2018)CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes. BMC Biol. Jul 5;16(1):73. doi: 10.1186/s12915-018-0541-4. Zhang Yan1, Yang Y, Zhu Z, Ou G.(2017) WASP-Arp2/3-dependent actin polymerization influences fusogen localization during cell-cell fusion in Caenorhabditis elegans embryos. Biology Open.:1324-1328. DOI: 10.1242/bio.026807. Yang, Y., Zhang, Yan1, Li, W-J., Jiang, Y., Zhu, Z., Hu, H., Li, W., Wu, J-W., Wang, Z-X., Dong, M-Q., Huang, S. and Ou, G.(2017) Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion. Developmental Cell. 41(1): 107-120. e4. Kang, E., Zheng, M., Zhang, Yan., Yuan, M., Yalovsky, S., Zhu, L., and Fu, Y. (2017). The microtubule-associated protein MAP18 affects ROP2 GTPase activity during root hair growth. Plant Physiology, pp-01243. Zhu, H., Chen, L., Yang, Y., Zhu, Z., Zhang, X., Li, W., Miao, L., Zhang, Yan. * and Ou, G. (2016). The Glial Actin Cytoskeleton Regulates Neuronal Ciliogenesis. Cell research. 27:448-451. Zhang, Yan.1, Kang, E., Yuan, M., Fu, Y., and Zhu, L. (2015). PCaP2 regulates nuclear positioning in growing Arabidopsis thaliana root hairs by modulating filamentous actin organization. Plant cell reports, 34(8), 1317-1330. Tian, D., Diao, M., Jiang, Y., Sun, L., Zhang, Yan., Chen, Z., Huang, S. and Ou, G. (2015). Anillin regulates neuronal migration and neurite growth by linking RhoG to the actin cytoskeleton. Current Biology, 25(9), 1135-1145. Zhu, L., Zhang, Yan.1, Kang, E., Xu, Q., Wang, M., Rui, Y., Liu, B., Yuan, M., and Fu, Y. (2013). MAP18 regulates the direction of pollen tube growth in Arabidopsis by modulating F-actin organization. The Plant Cell, 25(3), 851-867. Li, J.,J., Wang, X., L., Qin,T., Zhang, Yan.1, Liu, X., M., Sun, J., B., Zhou, Y., Zhu, L., Zhang, Z., D.,Ming, Y., and Mao, T., L.(2011). MDP25, A Novel Calcium Regulatory Protein, Mediates Hypocotyl Cell Elongation by Destabilizing Cortical Microtubules in Arabidopsis. Plant Cell 23: 4411-4427 Su, S., Z., Liu, Z., H., Chen, C., Zhang, Yan., Wang, X., Zhu, L., Miao, L., Wang, X., C., and Ming, Y. (2010). Cucumber mosaic virus movement protein severs actin filaments to increase the plasmodesmal size exclusion limit in tobacco. Plant Cell 22: 1373-1387 Chen, C., Zhang, Yan., Zhu, L., and Ming, Y.(2010). The actin cytoskeleton is involved in the regulation of the plasmodesmal size exclusion limit. Plant Signaling&Behavior 5:12,1-3

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