彭辰 - 中国农业大学

个人简介

彭辰，男，中国农业大学动物医学院教授，博士生导师，获国家自然科学基金人才项目、国家十四五重点研发计划青年科学家项目资助。博士毕业于美国堪萨斯州立大学（Kansas State University）生物学系，主要研究痘病毒宿主特异性的分子机制,曾获堪萨斯州立大学博士生论坛一等奖，L.Evans博士杰出研究奖等。博士后供职于美国洛克斐勒大学(The Rockefeller University)以及美国国立卫生研究院(National Institutes of Health, NIH)，主要致力于研究牛痘病毒拮抗天然免疫反应的分子机制。2021年以“杰出人才”加入中国农业大学动物医学院全职工作。任第十二届中国微生物学会兽医微生物专业委员会委员，中国饲料产业技术创新联盟常务理事，动物保健专委会委员，美国病毒学会（American Society of Virology）会员。任Frontiers in Cellular and Infection Microbiology编委（Member of the Editorial Board）,任PLoS Pathogens, Journal of Virology, Viruses 等杂志审稿人。工作经历 2016.6-2017.6 美国堪萨斯州立大学，博士后 2017.7-2018.1 美国洛克菲勒大学，博士后 2018.1-2020.12 美国国立卫生研究院（NIH）免疫与传染病研究所（NIAID）,博士后获奖及荣誉 2021年获农业农村部“农业科研杰出人才” 2021年获北京市科技新星

研究领域

主要研究方向包括牛痘、牛结节性皮肤病、羊痘病毒病原的复制机制以及免疫拮抗的分子机制；通过研发痘病毒抗病毒药物、疫苗、诊断试剂等，为牛痘、牛结节性皮肤病、猴痘等疫病的防控提供理论和技术支持；以改良牛痘病毒为载体研发针对各类传染病，如牛病毒性腹泻，新型冠状病毒肺炎等疫病的载体疫苗；开发靶向人或宠物癌症的新型溶瘤病毒治疗药物

近期论文

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（# 通讯作者） Peng, C., and Moss B., Repair of a newly identified host range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells. Proceedings of the National Academy of Sciences of USA. 2019 Peng, C., Wyatt, LS., Glushakow-Smith SG., Lal-Nag, M., Weisberg, AS., Moss, B., Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells. PLoS Pathogens. 2020 Peng, C., Zhou, Y., Cao, S., Pant, A., Campos Guerrero ML., et al. Identification of vaccinia virus inhibitors and cellular functions necessary for efficient viral replication by screening bioactive and FDA-approved drugs. Vaccines, 2020 Peng, C., Haller, S., Rahman, M., McFadden, G. and Rothenburg, S., Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates. Proceedings of the National Academy of Sciences of USA. 2016 Wang, P., Huang, S., Hao, C., Wang, Z., Wang, Z., Zhao, H., Liu, M., Tian, X., Ge, L., #Wu, W., #Peng, C., Establishment of a suspension MDBK cell line in serum-free medium for production of bovine alphaherpesvirus-1. Vaccines, 2021 Wang, Z., Liu, M., Zhao, H., Ma, W., Zhang, Y., #Wu, W., #Peng, C., Induction of robust and specific humoral and cellular immune responses by bovine viral diarrhea virus virus-like particles engineered with baculovirus expression system. Vaccines, 2021 Yu,H., Peng, C., Zhang, C. et al. Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway, Proceedings of the National Academy of Sciences of USA, 2022 Park, C., Peng, C., Rahman, MJ., Haller, SL., Tazi, L., Brennan, G., Rothenburg, S., Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR. PLoS Pathogens. 2021 Pant, A., Dsouza, L., Cao, S., Peng, C., Yang, Z., Viral growth factor and STAT3 signaling- dependent elevation of the TCA cycle intermediate levels during vaccinia virus infection. PLoS Pathogens. 2021