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个人简介

学习经历 2014年9月-2018年6月:中国农业大学,动物科学技术学院,博士 2010年9月-2013年6月:扬州大学,动物科学与技术学院,硕士 2006年9月-2010年6月:内蒙古农业大学,动物科学学院,学士 工作经历 2021年11月-至今:中国农业大学,动物科学技术学院,讲师 2020年7月-2021年11月:中国科学院动物研究所,干细胞与再生医学创新研究院,助理研究员 2018年7月-2020年6月:北京大学医学部,基础医学院,博士后(助理研究员) 2013年7月-2014年8月:中国农业大学,动物科学技术学院,科研助理 科研项目 2022-2023: 中国农业大学“人才培育支持计划”高水平创新团队(参与) 2020-2024: 国家自然科学基金重点项目,胃X/A样细胞在肝脏缺血再灌注损伤中的保护作用及机制(参与) 2018-2020: 中国博士后科学基金面上项目,毛螺菌科细菌抑制白色脂肪米色化的作用机制(主持) 2016-2019: 国家自然科学基金面上项目,4-羟基壬烯醛通过MAPK信号促进猪小肠上皮细胞凋亡、降低肠屏障功能的机理研究(参与) 2016-2019: 国家自然科学基金面上项目,脯氨酸促进胎猪生长发育的分子机制研究(参与) 社会服务工作 中国畜牧兽医学会(CAAV)动物营养学分会会员 中国营养学会(CNS)会员 中国生理学会(CAPS)会员 International Journal of Clinical Practice(Invited reviewer) 获得奖励与荣誉 北京大学医学部优秀博士后(2021年) 北京市优秀毕业生(2018年) 中国农业大学优秀毕业生(2018年)

研究领域

营养与肠道健康;营养与代谢性疾病

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Ji Y, Yang Y, Sun S, Dai Z, Ren F, Wu Z. Insights into diet-associated oxidative pathomechanisms in inflammatory bowel disease and protective effects of functional amino acids. Nutrition Reviews. 2022. Accepted. Ji Y, He Y, Yang Y, Dai Z, Wu Z. Hydroxyproline alleviates 4-hydroxy-2-nonenal-induced DNA damage and apoptosis in porcine intestinal epithelial cells. Animal Nutrition, 2022, 9: 7-15. Ji Y#, Fang S#, Yang Y, Wu Z. Inactivation of the Wnt/beta-catenin signaling contributes to the epithelial barrier dysfunction induced by sodium oxalate in canine renal epithelial cells. Journal of Animal Science, 2021, 99(10). (#co-first author) Ji Y#, Fan X#, Zhang Y, Li J, Dai Z, Wu Z. Glycine regulates mucosal immunity and the intestinal microbial composition in weaned piglets. Amino Acids, 2022, 54(3): 385-398. (#co-first author) Ji Y, Yin Y, Sun L, Zhang W. The Molecular and Mechanistic Insights Based on Gut-Liver Axis: Nutritional Target for Non-Alcoholic Fatty Liver Disease (NAFLD) Improvement. International journal of molecular sciences. 2020, 21(9), doi: 10.3390/ijms21093066. Ji Y, Yin W, Liang Y, Sun L, Yin Y, Zhang W. Anti-Inflammatory and Anti-Oxidative Activity of Indole-3-Acetic Acid Involves Induction of HO-1 and Neutralization of Free Radicals in RAW264.7 Cells. International journal of molecular sciences. 2020, 21(5). doi: 10.3390/ijms21051579. Ji Y, Yin Y, Zhang W. Integrated Bioinformatic Analysis Identifies Networks and Promising Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma. International Journal of Genomics.2020 Jul 28;2020:2061024. doi: 10.1155/2020/2061024. Ji Y, Gao Y, Chen H, Yin Y, Zhang W. Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress. Nutrients,2019,11, doi:10.3390/nu11092062. Ji Y, Yin Y, Li Z, Zhang W. Gut Microbiota-Derived Components and Metabolites in the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD). Nutrients, 2019, 11, doi:10.3390/nu11081712. Ji Y, Dai Z, Sun S, Ma X, Yang Y, Tso P, Wu G, Wu Z. Hydroxyproline attenuates dextran sulfate sodium-induced colitis in mice: involvment of the NF-κB signaling and oxidative stress. Molecular Nutrition and Food Research, 2018; doi.org/10.1002/mnfr.201800494 Ji Y, Luo X, Yang Y, Dai Z, Wu G, Wu Z. Endoplasmic reticulum stress-induced apoptosis in intestinal epithelial cells: a feed-back regulation by mechanistic target of rapamycin complex 1 (mTORC1). Journal of Animal Science and Biotechnology, 2018; 9: 38. Ji Y, Wu Z, Dai Z, Wang X, Li J, Wang B, Wu G. Fetal and neonatal programming of postnatal growth and feed efficiency in swine. Journal of Animal Science and Biotechnology, 2017; 8(1): 42. Ji Y, Dai Z, Wu G, Wu Z. 4-Hydroxy-2-nonenal induces apoptosis by activating ERK1/2 signaling and depleting intracellular glutathione in intestinal epithelial cells. Scientific reports, 2016;6:32929. Ji Y, Wu Z, Dai Z, Sun K, Zhang Q, Wu G. Excessive L-cysteine induces vacuole-like cell death by activating endoplasmic reticulum stress and mitogen-activated protein kinase signaling in intestinal porcine epithelial cells. Amino acids, 2016;48(1):149-56. Ji Y, Wu Z, Dai Z, Sun K, Wang J, Wu G. Nutritional epigenetics with a focus on amino acids: implications for the development and treatment of metabolic syndrome. Journal of nutritional biochemistry, 2016;27:1-8. Wang MZ#, Ji Y#, Wang C, Chen LM, Wang HR, Loor, JJ. The preliminary study on the effects of growth hormone and insulin-like growth factor-I on kappa-casein synthesis in bovine mammary epithelial cells in vitro. Journal of Animal Physiology and Animal Nutrition. 2016 Apr;100(2):251-5. (#co-first author) Yang Y, Fan X, Ji Y, Li J, Dai Z, Wu Z. Glycine represses endoplasmic reticulum stress-related apoptosis and improves intestinal barrier by activating mammalian target of rapamycin complex 1 signaling[J]. Animal Nutrition, 2022, 8(1): 1-9. Liu N, Ji Y, Yang Y, Jia H, Si X, Jiang D, Zhang Y, Dai Z, Wu Z. Impact of Dietary Crude Protein Level on Hepatic Lipid Metabolism in Weaned Female Piglets. Animals. 2021.Jun 18;11(6):1829. Yang Y, Ji Y, Wu G, Sun K, Dai Z, Wu Z. Dietary L-methionine restriction decreases oxidative stress in porcine liver mitochondria. Experimental gerontology. 2015; 65:35-41. Wang B, Wu Z, Ji Y, Sun K, Dai Z, Wu G. L-Glutamine Enhances Tight Junction Integrity by Activating CaMK Kinase 2-AMP-Activated Protein Kinase Signaling in Intestinal Porcine Epithelial Cells. The Journal of nutrition. 2016;146(3):501-508. Sun K, Wu Z, Ji Y, Wu G. Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts. The Journal of nutrition, 2016; 146(12): 2461-2467. Liang H, Dai Z, Liu N, Ji Y, Chen J, Zhang Y, Yang Y, Li J, Wu Z, Wu G. Dietary L-Tryptophan Modulates the Structural and Functional Composition of the Intestinal Microbiome in Weaned Piglets. Frontiers in Microbiology, 2018, 9, 1736, doi:10.3389/fmicb.2018.01736. Lei J, Wang S, Kang W, Chu Q, Liu Z, Sun L, Ji Y, Esteban CR, Yao Y, Belmonte JCI, Chan P, Liu GH, Zhang W, Song M, Qu J. FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction. Protein & Cell. 2021,12(2):145-151. Fan T, Wang S, Jiang Z, Ji S, Cao W, Liu W, Ji Y, Li Y, Shyh-Chang N, Gu Q. Controllable assembly of skeletal muscle-like bundles through 3D bioprinting. Biofabrication. 2021, 14(1): 015009.

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