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个人简介

学习经历 2015.09-2019.07:中国农业大学动物科学技术学院,博士 2008.09-2015.07:山东农业大学动物科技学院,学士、硕士 工作经历 2022.10-至今:中国农业大学动物科学技术学院,副教授 2020.10-2022.09:中国农业大学食品科学与营养工程学院,博士后 2019.07-2020.08:北京协和医学院中国医学科学院医药生物技术研究所,助理研究员 科研项目 2021-2023:国家自然科学基金青年项目,主持 2020-2022:中国博士后科学基金面上项目,主持 2019-2021:动物营养学国家重点实验室开放课题,主持 2021-2025:现代农业产业技术体系建设项目-兔,CARS-44-A-5,团队成员 2022-2025:“十四五”国家重点研发专项“牦牛乳高值化加工关键技术研发“,骨干参与 2016-2021:国家自然科学基杰出青年项目,参与 2016-2019:国家自然科学基金面上项目,骨干参与 社会服务工作 第105批中国博士后科技服务团(东川行) Journal of Animal Physiology and Animal Nutrition审稿人 Annals of Hepatology审稿人

研究领域

营养与繁殖;肠道微生物与肠上皮细胞互作;免疫及肠道健康

近期论文

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Liu, N., Yang, Y., Chen, J., Jia, H., Zhang, Y., Jiang, D., Wu, G., Wu, Z., 2020. 3-Acetyldeoxynivalenol induces lysosomal membrane permeabilization-mediated apoptosis and inhibits autophagic flux in macrophages. Environmental Pollution 265: 114697. Liu, N., Ma, X., Luo, X., Zhang, Y., He, Y., Dai, Z., Yang, Y., Wu, G., Wu, Z., 2018. l-Glutamine Attenuates Apoptosis in Porcine Enterocytes by Regulating Glutathione-Related Redox Homeostasis. Journal of Nutrition 148: 526-534. Liu, N., Dai, Z., Zhang, Y., Chen, J., Yang, Y., Wu, G., Tso, P., Wu, Z., 2019. Maternal L-proline supplementation enhances fetal survival, placental development, and nutrient transport in mice. Biology of Reproduction 100: 1073-1081. Liu, N., Yang, Y., Si, X., Jia, H., Zhang, Y., Jiang, D., Dai, Z., Wu, Z., 2021. L-Proline Activates Mammalian Target of Rapamycin Complex 1 and Modulates Redox Environment in Porcine Trophectoderm Cells. Biomolecules. 11(5): 742. Liu, N. #, Sun, S. #, Wang, P., Sun, Y., Hu, Q., Wang, X., 2021. The Mechanism of Secretion and Metabolism of Gut-Derived 5-Hydroxytryptamine. Int J Mol Sci. 22(15): 7931. Liu, N., Chen, J., He, Y., Jia, H., Jiang, D., Li, S., Yang, Y., Dai, Z., Wu, Z., Wu, G., 2020. Effects of maternal L-proline supplementation on inflammatory cytokines at the placenta and fetus interface of mice. Amino Acids 52: 587-596. Liu N., Feng G., Zhang X., Hu Q., Sun S., Sun J., Sun Y., Wang R., Zhang Y., Wang P., Li Y., 2021 The Functional Role of Lactoferrin in Intestine Mucosal Immune System and Inflammatory Bowel Disease. Front Nutr. 25(8): 759507. Li, Y.#, Liu, N.#, Ge, Y., Yang, Y., Ren, F., Wu, Z. 2022 Tryptophan and the innate intestinal immunity: Crosstalk between metabolites, host innate immune cells, and microbiota. Eur J Immunol 52: 856-868. Liu, N., Dai, Z., Zhang, Y., Jia, H., Chen, J., Sun, S., Wu, G., Wu, Z., 2019. Maternal L-proline supplementation during gestation alters amino acid and polyamine metabolism in the first generation female offspring of C57BL/6J mice. Amino Acids 51: 805-811. Liu, N., Ji, Y., Yang, Y., Jia, H., Si, X., Jiang, D., Zhang, Y., Dai, Z., Wu, Z., 2021. Impact of Dietary Crude Protein Level on Hepatic Lipid Metabolism in Weaned Female Piglets. Animals (Basel). 11(6): 1829. Liu, N., Yang, L., Yang, W.R., Jiang, S.Z., Zhang, G.G., Niu, Q.S., Qian, X., Yang, Z.B., 2016. Effects of feeding naturally contaminated diet with zearalenone, fumonisin and deoxynivalenol with or without yeast cell wall adsorbent on growth, vulva size and organ weights of gilts. Journal of Animal and Feed Sciences 25: 145-151. Zhang, S., Jin, W., Zhang, W., Ren, F., Wang, P., Liu, N., 2022 Pea Albumin Attenuates Dextran Sulfate Sodium-Induced Colitis by Regulating NF-κB Signaling and the Intestinal Microbiota in Mice. Nutrients 14: 17:3611. Liu, N., Song, Z., Jin, W., Yang, Y., Sun, S., Zhang, Y., Zhang, S., Liu, S., Ren, F., Wang, P., 2022 Pea albumin extracted from pea (Pisum sativum L.) seed protects mice from high fat diet-induced obesity by modulating lipid metabolism and gut microbiota, Journal of Functional Foods, 97: 105234. Zhang, Y., Si, X., Yang, L., Wang, H., Sun, Y.#, Liu, N. #, 2022 Association between intestinal microbiota and inflammatory bowel disease 5(4): 311-322. Jia, H., Liu, N., Zhang, Y., Wang, C., Yang, Y., Wu, Z., 2021. 3-Acetyldeoxynivalenol induces cell death through endoplasmic reticulum stress in mouse liver. Environ Pollut. 286:117238. Si, X., Liu N., Jia H., Wang J., Pan L., Dong L., Rong Z., Yang Y., Wu Z. Gut relief formula attenuates dextran sulfate sodium-induced colitis by regulating NF-κB signaling and the intestinal microbiota in mice. Food Funct. 2021, 12(21):10983-10993. 5.536 Wang, R., Liu, N., Yang, Y., Lei, Y., Lyu. J., Dai, Z., Kim, I H., Li, Ju., Wu, Z., Li, D., 2021. Flavor supplementation during late gestation and lactation periods increases the reproductive performance and alters fecal microbiota of the sows. Animal Nutrition. 7(3):679-687. Liang, H., Liu, N., Wang, R., Zhang, Y., Chen, J., Dai, Z., Yang, Y., Wu, G., Wu, Z., 2020. N-Acetyl Serotonin Alleviates Oxidative Damage by Activating Nuclear Factor Erythroid 2-Related Factor 2 Signaling in Porcine Enterocytes. Antioxidants (Basel) 9. Liang, H., Dai, Z., Liu, N., Ji, Y., Chen, J., Zhang, Y., Yang, Y., Li, J., Wu, Z., Wu, G., 2018. Dietary L-Tryptophan Modulates the Structural and Functional Composition of the Intestinal Microbiome in Weaned Piglets. Frontiers in Microbiology 9, 1736. Li, S., Zhang, Y., Liu, N., Chen, J., Guo. L., Dai. Z., Wang. C., Wu Z., Wu G., 2020. Dietary L-arginine supplementation reduces lipid accretion by regulating fatty acid metabolism in Nile tilapia (Oreochromis niloticus). Journal of Animal Science and Biotechnology 11:82. Yang, Y., Li, C., Liu, N., Wang, M., Zhou, X., Kim, IH., Wu, Z., 2021. Ursolic acid alleviates heat stress-induced lung injury by regulating endoplasmic reticulum stress signaling in mice. J Nutr Biochem. 2021 89:108557. Pang, X., Zhao, J., Liu, N., Chen, M.,Ma, B., 2020. Anthraquinone analogues with inhibitory activities against influenza a virus from Polygonatum odoratum. Journal of Asian Natural Products Research. 1-7. He, Y., Fan, X., Liu, N., Song, Q., Kou, J., Shi, Y., Luo, X., Dai, Z., Yang, Y., Wu, Z., Wu, G., 2019. l-Glutamine Represses the Unfolded Protein Response in the Small Intestine of Weanling Piglets. Journal of Nutrition 149, 1904-1910. Wang, B., Sun, S., Liu, M., Chen, H., Liu, N., Wu, Z., Wu, G., Dai, Z., 2020. Dietary L-Tryptophan Regulates Colonic Serotonin Homeostasis in Mice with Dextran Sodium Sulfate-Induced Colitis. Journal of Nutrition. Zhang, Y., Jia, H., Jin, Y., Liu, N., Chen, J., Yang, Y., Dai, Z., Wang, C., Wu, G., Wu, Z., 2020. Glycine Attenuates LPS-Induced Apoptosis and Inflammatory Cell Infiltration in Mouse Liver. Journal of Nutrition 150, 1116-1125. Zhang, X., Chen, S., Zhang, M., Ren, F., Ren, Y., Li, Y., Liu, N., Zhang, Y., Zhang, Q., Wang, R., 2021. Effects of Fermented Milk Containing Lacticaseibacillus paracasei Strain Shirota on Constipation in Patients with Depression: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 13(7):2238.

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