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Yu H T#, Ma Z X#, Meng S Y, Qiao S Y, Zeng X F, Tong Z H, Jeong K C. A novel nanohybrid antimicrobial based on chitosan nanoparticles and antimicrobial peptide microcin J25 with strong antibacterial activity and low toxicity. Carbohydrate Polymers, 2021, 253:117309.
Yu H T, Shang L J, Yang G X, Dai Z Q, Zeng, X F, Qiao S Y. Biosynthetic microcin J25 exerts strong antibacterial, antiinflammatory activities, low cytotoxicity without increasing drugresistance to bacteria target. Frontiers in Immunology, 2022, 13, 811378.
Yu H T, Wang Y M, Zeng X F, Cai S, Wang G, Liu L, Huang S, Li N, Liu H B, Ding X L, Song Q L, Qiao S Y. Therapeutic administration of the recombinant antimicrobial peptide microcin J25 effectively enhances host defenses against gut inflammation and epithelial barrier injury induced by enterotoxigenic Escherichia coli infection. The FASEB Journal, 2020, 34(1):1018-1037.
Yu H T, Shang L J, Zeng X F, Li, N, Liu H B, Cai S, Huang S, Wang G, Wang Y M, Song Q L, Qiao S Y. Risks related to high-dosage recombinant antimicrobial peptide microcin J25 in mice Model: Intestinal microbiota, intestinal barrier function and immune regulation. Journal of Agricultural and Food Chemistry, 2018, 66(43):11301-11310.
Yu H T, Chen Y F, Sun M C, Han S J. A novel polymeric nanohybrid antimicrobial engineered by antimicrobial peptide mccj25 and chitosan nanoparticles exerts strong antibacterial and anti-inflammatory activities. Frontiers in Immunology, 2022, 12, 811381.
Yu H T, Li N, Zeng X F, Liu L, Wang Y M, Wang G, Cai S, Huang S, Ding X L, Song Q L, Qiao S Y. A comprehensive antimicrobial activity evaluation of the recombinant antimicrobial peptide microcin J25 against the foodborne pathogens Salmonella and E. coli O157 and its potential beneficial effects as an antimicrobial agent. Frontiers in Microbiology, 2019, 10:1954 .
Yu H T, Zhang J Q, Sun M C, Chen, H, Shi X M. Polymeric Nanohybrids Engineered by Chitosan Nanoparticles and Bioactive Peptides as Novel Antimicrobials in Food Biopreservatives: Risk Assessment and Anti-Foodborne Pathogen E. coli O157:H7 Infection by Immune Regulation. Journal of Agricultural and Food Chemistry, 2022, 70(39):12535-12549.
Yu H T, Ding X L, Shang L J, Zeng X F, Liu H B, Li N, Huang S, Wang Y M, Wang G, Cai S, Chen M X, Levesque C L, Johnston L J, Qiao S Y. Protective ability of biogenic antimicrobial peptide microcin J25 against enterotoxigenic Escherichia coli-induced intestinal epithelial dysfunction and inflammatory responses IPEC-J2 cells. Frontiers in Cellular and Infection Microbiology, 2018, 8:242.
Yu H T, Ding X L, Li N, Zhang X Y, Zeng X F, Wang S, Liu H B, Wang Y M, Jia H M, Qiao S Y. Dietary supplemented antimicrobial peptide microcin J25 improves the growth performance, apparent total tract digestibility, fecal microbiota, and intestinal barrier function of weaned pigs. Journal of Animal Science, 2017, NOV, 95(11):5064-5076.
Kuang M#, Yu H T#,*, Qiao S Y, Huang T, Zhang J Q, Sun M C, Shi X M, Chen H. A novel nano-antimicrobial polymer engineered with Chitosan nanoparticles and bioactive peptides as promising Food biopreservative effective against foodborne pathogen E. Coli O157-caused epithelial barrier dysfunction and inflammatory responses. International Journal of Molecular Sciences, 2021, 22, 13580. .
Liu T T#, Yu H T#, Zhang Z M#, Xie Y F, Yang L, You F P. Intestinal ELF4 deletion exacerbates alcoholic liver disease by disrupting gut homeostasis. International Journal of Molecular Sciences, 2022, 23, 4825.
Zi-qi Dai, Li-jun Shang, Yu-shu Wei, Ze-qiang Li, Xiang-fang Zeng, Mei-xia Chen, Xin-yu Wang, Si-yu Li, Shiyan Qiao, Haitao Yu*. Immunomodulatory Effects of Microcin C7 in Cyclophosphamide-Induced Immunosuppressed Mice. Journal of Agricultural and Food Chemistry, 2023, In Press.
Lijun Shang, Fengjuan Yang, Yushu Wei, Ziqi Dai, Qingyun Chen, Xiangfang Zeng, Shiyan Qiao, Haitao Yu *. Multi-omics analysis reveals gut microbiota characteristics in diarrheal piglets treated with gentamicin. Antibiotics, 2023, In Press.
Guangxin Yang, Lijun Shang, Lu Liu, Zeqiang Li, Xiangfang Zeng, Xiuliang Ding, Jinxiu Huang, Shiyan Qiao, Haitao Yu *. Engineering and Purification of Microcin C7 Variants Resistant to Trypsin and Analysis of Their Biological Activity. Antibiotics, 2023, In Press.
于海涛, 周智旋, 陆文清. 角蛋白酶水解豆粕的微生物多样性分析[J]. 微生物学通报, 2019, 46(4): 729-740
于海涛, 周智旋, 耿正颖, 陆文清. 角蛋白酶体外酶解豆粕对其营养价值的影响和在断奶仔猪生产中的应用. 中国畜牧杂志, 2019, 55(07):122-127
于海涛, 周智旋, 张波, 孙得发, 陆文清. 酶解豆粕工艺参数的探索和优化[J]. 中国畜牧杂志, 2018, 54(9):77-83
Shang L J, Yu H T, Liu H B, Chen M X, Zeng X F, Qiao S Y. Recombinant antimicrobial peptide microcin J25 alleviates DSS-induced colitis via regulating intestinal barrier function and modifying gut microbiota. Biomed Pharmacother. 2021, 139:111127.
Ding X L, Yu H T, Qiao S Y. Lasso peptide Microcin J25 Effectively Enhances Gut Barrier Function and Modulates Inflammatory Response in an Enterotoxigenic Escherichia Coli-Challenged Mouse Model [J]. International Journal of Molecular Sciences, 2020, 21(18), 6500
Shang L J, Liu H B, Yu H T, Chen M X, Yang T R, Zeng X F, Qiao S Y. Core Altered Microorganisms in Colitis Mouse Model: A Comprehensive Time-Point and Fecal Microbiota Transplantation Analysis. Antibiotics, 2021, 10(6), 643.
Han S J, Yu H T, Yang F F, Qiao S Y, He P L. Effect of dietary supplementation with hyperimmunized hen egg yolk powder on diarrhoea incidence and intestinal health of weaned pigs. Food and Agricultural Immunology, 2019, 30(1):333-348.
Wang Y M, Yu H T, Zhou J Y, Zeng X F, Wang G, Cai S, Huang S, Zhu Z P, Tan J J, Johnston L J, Levesque C L, Qiao S Y. Effects of feeding growing-finishing pigs with low crude protein diets on growth performance, carcass characteristics, meat quality and nutrient digestibility in different areas of China. Animal Feed Science and Technology, 2019, 256:114256.
Li N, Yu H T, Liu H B, Wang Y M, Zhou J Y, Ma X, Wang Z, Sun C T, Qiao S Y. Horizontal transfer of vanA between probiotic Enterococcus faecium and Enterococcus faecalis in fermented soybean meal and in digestive tract of growing pigs. Journal of Animal Science and Biotechnology, 2019, 10:36.
Jia H M, He T, Yu H T, Zeng X F, Zhang S H, Ma W F, Zhang J, Qiao S Y, Ma X. Effects of L-lysine·H2SO4 product on the intestinal morphology and liver pathology using broiler model. Journal of Animal Science and Biotechnology, 2019, 10:10.
Jiaqi Zhang, Haitao Yu, Huiyan Zhang, Qingyu Zhao, Wei Si, Yuchang Qin, Junmin Zhang. Dietary Epimedium extract supplementation improves intestinal functions and alters gut microbiota in broilers. Journal of Animal Science and Biotechnology, 2023 Jan 18;14(1):14.
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