个人简介
学习经历
2013.09-2018.06，中国农业大学，临床兽医学专业，博士生
2009.09-2013.06，安徽农业大学，动物医学专业，本科生
工作经历
2020.07-至今，中国农业大学动物科技学院，副教授
2018.07-2020.06，中国农业大学，畜牧学博士后流动站，博士后
科研项目
国家自然科学基金面上项目：PTP1B介导巨噬细胞源外泌体改善仔猪肠上皮屏障功能的机制研究（2022.01-2025.12）
国家自然科学基金青年科学基金项目：乳脂球膜介导M2巨噬细胞分型调控IUGR仔猪肠炎的分子机制（2020.01-2022.12）
中国博士后科学基金面上项目：NLRP6炎性体调控AHLs诱发猪肠上皮细胞炎性损伤的机制（2018.11-2020.06）
中国农业大学基本科研业务费专项资金项目：乳脂球膜缓解IUGR仔猪肠炎的机制研究（2020.01-2020.11）
近期论文
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Shilan Wang, Shiyi Zhang, Shimeng Huang, Zhenhua Wu, Jiaman Pang, Yujun Wu, Junjun Wang, Dandan Han*. Resistant maltodextrin alleviates dextran sulfate sodium-induced intestinal inflammatory injury by increasing butyric acid to inhibit proinflammatory cytokine levels. BioMed Research International. 2020, 2020: 7694734.
Dandan Han, Lili Jiang, Xiaolong Gu, Shimeng Huang, Jiaman Pang, Yujun Wu, Jingdong Yin, Junjun Wang*. SIRT3 deficiency is resistant to autophagy-dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels. Journal of Cellular Physiology. 2020, 235: 8839-8851.
Dandan Han, Xiaolong Gu, Jian Gao, Zhi Wang, Gang Liu, Herman W Barkema, Bo Han*. Chlorogenic acid promotes the Nrf2/HO-1 anti-oxidative pathway by activating p21Waf1/Cip1 to resist dexamethasone-induced apoptosis in osteoblastic MC3T3-E1 cells. Free Radical Biology Medicine. 2019, 137: 1-12.
Dandan Han, Jian Gao, Xiaolong Gu, Jan Georg Hengstler, Limei Zhang, Muhammad Shahid, Tariq Ali, Bo Han*. P21Waf1/Cip1 depletion promotes dexamethasone-induced apoptosis in osteoblastic MC3T3-E1 cells by inhibiting the Nrf2/HO-1 pathway. Archives of Toxicology. 2018, 92(2): 679-692.
Dandan Han#, Wei Chen#, Xiaolong Gu, Ruixue Shan, Jiaqi Zou, Gang Liu, Muhammad Shahid, Jian Gao, Bo Han*. Cytoprotective effect of chlorogenic acid against hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells through PI3K/Akt-mediated Nrf2/HO-1 signaling pathway. Oncotarget. 2017, 8(9): 14680-14692.
Dandan Han, Changrong Wan, Fenghua Liu*, Xiaolong Xu, Linshu Jiang*, Jianqin Xu*. Jujuboside A protects H9C2 cells from isoproterenol-induced injury via activating PI3K/Akt/mTOR signaling pathway. Evidence-Based Complementary Alternative Medicine. 2016, doi: 10.1155/2016/9593716.
Changrong Wan#, Dandan Han#, Jianqin Xu, Peng Yin, Xiaolong Xu, Chen Mei, Fenghua Liu*, Zhaofei Xia*. Jujuboside A attenuates norepinephrine-induced apoptosis in H9c2 cardiomyocytes by modulating MAPK and AKT signaling pathways. Molecular Medicine Reports. 2018, 17(1): 1131-1140.
庞家满, 王军军, 王春林, 谈苏贞, 杨富裕, 张燕, 赵应堂, 韩丹丹*. 辣木叶替代不同水平豆粕对生长猪生长性能的影响[J]. 中国畜牧杂志, 2021, doi: 10.19556/j.0258-7033.20201217-07.
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