研究领域
Our research interests primarily focus on biomaterials and biomolecular assemblies, including lamellar and non-lamellar lipid bilayer structures, amyloid protein and peptide fibrils, and elastic protein networks. We are interested in developing methods to control, align and investigate these systems without their needing to be dehydrated or crystallised. Molecular alignment gives us a wealth of additional structural information on the biomolecules, using x-ray scattering and polarized vibrational spectroscopy (IR and Raman).
In addition, the group has an interest in developing interactive animations and demonstrations based on Adobe (Macromedia) Flash, for use in teaching.
近期论文
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Seddon, A. M., Richardson, S. J., Rastogi, K., Plivelic, T. S., Squires, A. M. and Pfrang, C. (2016) Control of nanomaterial self-assembly in ultrasonically levitated droplets. Journal of Physical Chemistry Letters, 7 (7). pp. 1341-1345. ISSN 1948-7185 doi: 10.1021/acs.jpclett.6b00449
Richardson, S. J., Burton, M. R., Staniec, P. A., Nandhakumar, I. S., Terrill, N.J., Elliott, J. and Squires, A. (2016) Aligned platinum nanowire networks from surface-oriented lipid cubic phase templates. Nanoscale, 8 (5). pp. 2850-2856. ISSN 2040-3364 doi: 10.1039/c5nr06691c
Asghar, K. A., Rowlands, D. A., Elliott, J. M. and Squires, A. M. (2015) Predicting sizes of hexagonal and gyroid metal nanostructures from liquid crystal templating. ACS Nano, 9 (11). pp. 10970-10978. ISSN 1936-086X doi: 10.1021/acsnano.5b04176
Squires, A. M., Akbar, S., Tousley, M. E., Rokhlenko, Y., Singer, J. P. and Osuji, C. O. (2015) Experimental evidence for proposed transformation pathway from the inverse hexagonal to inverse diamond cubic phase from oriented lipid samples. Langmuir, 31 (28). pp. 7707-7711. ISSN 0743-7463 doi: 10.1021/acs.langmuir.5b01676
Richardson, S. J., Staniec, P. A., Newby, G. E., Rawle, J. L., Slaughter, A. R., Terrill, N. J., Elliott, J. and Squires, A. (2015) Glycerol prevents dehydration in lipid cubic phases. Chemical Communications, 51 (57). pp. 11386-11389. ISSN 1359-7345 doi: 10.1039/c5cc03771a
Richardson, S. J., Staniec, P. A., Newby, G. E., Terrill, N. J., Elliott, J. M., Squires, A. M. and Góźdź, W. T. (2014) Predicting the orientation of lipid cubic phase films. Langmuir, 30 (45). pp. 13510-13515. ISSN 0743-7463 doi: 10.1021/la503313n
Seddon, A. M., Hallett, J., Beddoes, C., Plivelic, T. S. and Squires, A. M. (2014) Experimental confirmation of transformation pathways between inverse double diamond and gyroid cubic phases. Langmuir, 30 (20). pp. 5705-5710. ISSN 0743-7463 doi: 10.1021/la5005837
Rittman, M., Amenitsch, H., Rappolt, M., Sartori, B., O’Driscoll, B.M.D. and Squires, A. M. (2013) Control and analysis of oriented thin films of lipid inverse bicontinuous cubic phases using grazing incidence small-angle X‑ray scattering. Langmuir, 29 (31). pp. 9874-9880. ISSN 0743-7463 doi: 10.1021/la401580y