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研究领域

Neuroendocrinology and Molecular Endocrinology with an emphasis on behaviour using physiologically relevant model systems. Mechanisms of estrogen action in neuronal cells, including an emphasis on non-genomic and non-transcriptional signalling and their relevance to behaviour. Mechanisms by which GPR30, a putative membrane Estrogen Receptor (mER) signals in neurons and the relevance to behaviour. Role of locally synthesized steroids and their relevance to social behaviors. Role of thyroid hormones in the regulation of anxiety and cognition.

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Fisher, M. and Vasudevan, N. (2015) Cognition and anxiety are regulated by thyroid hormone signaling. Immunology‚ Endocrine and Metabolic Agents in Medicinal Chemistry, 15 (1). pp. 60-70. ISSN 1875-5844 doi: 10.2174/187152221501150710130829 Clark, S., Pollard, K., Rainville, J. and Vasudevan, N. (2015) Detection of the phosphorylation of the estrogen receptor alpha as an outcome of GPR30 activation. In: Eyster, K. M. (ed.) Estrogen receptors: methods and protocols. Methods in Molecular Biology, 1366. Humana Press, New York, pp. 457-470. ISBN 9781493931262 doi: 10.1007/978-1-4939-3127-9_36 Rainville, J., Pollard, K. and Vasudevann, N. (2015) Membrane-initiated non-genomic signaling by estrogens in the hypothalamus: cross-talk with glucocorticoids with implications for behavior. Frontiers in Endocrinology, 6. 18. ISSN 1664-2392 doi: 10.3389/fendo.2015.00018 Hawley, W. R., Grissom, E. M., Moody, N. M., Dohanich, G. P. and Vasudevan, N. (2014) Activation of G-protein-coupled receptor 30 is sufficient to enhance spatial recognition memory in ovariectomized rats. Behavioural Brain Research, 262. pp. 68-73. ISSN 0166-4328 doi: 10.1016/j.bbr.2014.01.006 Hart, D., Nilges, M., Pollard, K., Lynn, T., Patsos, O., Shiel, C., Clark, S. M. and Vasudevan, N. (2014) Activation of the G-protein coupled receptor 30 (GPR30) has different effects on anxiety in male and female mice. Steroids, 81. pp. 49-56. ISSN 0039-128X doi: 10.1016/j.steroids.2013.11.004

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