赵心彬 - 北京航空航天大学 - 医学科学与工程学院 / 医工交叉创新研究院

个人简介

教育背景 2015.9-2018.10 清华大学药学院博士学位 2010.9-2013.6 第二军医大学长征医院硕士学位 2006.9-2010.6 江苏大学药学院学士学位工作经历 2018.11-2021.12 北京航空航天大学生物与医学工程学院博士后 2013.7-2015.8 清华大学医学院科研助理代表性科研项目国家自然科学基金青年基金，11902020，2020.01-2022.12，20万元，在研，主持中国博士后科学基金面上资助，2019M660390, 2019.05-2021.12，8万元，结题，主持北航青年拔尖人才计划，2022.6-2026.12，50万元，在研，主持国家自然科学基金面上项目，81470839，2015/01-2018/12，120万元，已结题，参与

研究领域

材料、生物、医学交叉等多学科交叉细胞外基质材料对干细胞分化和保持干性的研究肿瘤细胞迁移浸润过程中的生物力学机制肿瘤细胞微环境中巨噬细胞极化的研究

近期论文

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Xin-Bin Zhao, Yun-Ping Chen, Min Tan, ..., Xi-Qiao Feng, Jing Du,* and Yu-Bo Fan*. Extracellular Matrix Stiffness Regulates DNA Methylation by PKCα-Dependent Nuclear Transport of DNMT3L. (2021). Advanced Healthcare Materials. 2100821. Xinbin Zhao, Yuecheng Ding, Jing Du, Yubo Fan. 2020 update on human coronaviruses: One health, one world. (2020). Medicine in Novel Technology and Devices. 8,100043. Liangliang Ji#, Xinbin Zhao#, ..., Ligong Chen* and Xiaoyu Hu*. Slc6a8-mediated creatine uptake and accumulation reprogram macrophage polarization via regulating cytokine responses. (2019). Immunity. 51, 272-284. Yunan Luo#, Xinbin Zhao#, Jingtian Zhou#, ..., Ligong Chen* and Jianyang Zeng*. (2017). A network integration approach for drug-target interaction prediction and computational drug repositioning from heterogeneous information. Nature Communications, 8, 573-586. Xinbin Zhao, ..., Siegenthaler Julie A and Ligong Chen*. (2017). Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Scientific Reports, 7, 46344-46359. Xinbin Zhao, ..., Fuming Shen, Xiao Tao*. (2014). Simvastatin attenuates radiation-induced tissue damage in mice. Journal of Radiation Research. 5,257-264. Wenhua Kuang, ..., Xinbin Zhao, ..., Ligong Chen. SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility. (2020). Cell Reports. 35, 109025. Lili Cheng, Mengmeng Ge, ..., Xinbin Zhao, ..., Ligong Chen*. Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity. (2018). Archives Toxicology. 92, 469-485. Hong Yang, Fei Huang, Yulong Tao, Xinbin Zhao, Lina Liao, Xia Tao. Simvastatin ameliorates ionizing radiation-induced apoptosis in the thymus by activating the AKT/sirtuin 1 pathway in mice. (2017). International Journal of Molecular Medicine. 40: 762-770, 2017 Ung Peter Man-Un, Wenxin Song, Lili Cheng, Xinbin Zhao, Hailin Hu, Ligong Chen* and Schlessinger Avner*. Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening.(2016). ACS Chemical Biology. 11, 1908?1916. Haiping Tang, ..., Ligong Chen, Xinbin Zhao, Haiteng Deng, Xiaohui Liu. Establishment of local searching methods for orbitrap-based high throughput metabolomics analysis. (2016). Talanta156-157,163-171. Hong Yang, Fei Huang, Min Ni, Xinbin Zhao, Ya-Ping Deng, Jia-Wen Yu, Guo-Jun Jiang and Xia Tao. Cognitive Function is Impaired by Obesity and Alleviated by Lorcaserin Treatment in Mice. (2015). CNS. Neuroscience & Therapeutics. 21, 472-474 Jikuai Chen, Zhangpeng Li, Yunzi Liu, Ting Zhao, Xinbin Zhao, Min Ni, Guojun Jiang * and Fuming Shen *. Activation of Alpha 7 Nicotinic Acetylcholine Receptor Protects Mice from Radiation-Induced Intestinal Injury and Mortality. (2014). Radiation Research. 181, 666-671.