个人简介
教育背景
2014-09至2019-06，中国科学院化学研究所，化学，博士
2010-09至2014-06，郑州大学，材料科学与工程，学士
工作经历
2021-12至今，北京航空航天大学，医学科学与工程学院，助理教授
2019-07至2021-12, 北京航空航天大学，博士后，导师: 田捷
代表性科研项目
科技部，国家重点研发计划“纳米科技”重点专项，2017YFA0205200，基于近红外纳米探针的肝癌分子影像及其手术导航技术研发，2017.07-2022.06，课题骨干
国家自然科学基金委员会，国家重大科研仪器研制专项，62027901，基于磁纳米粒子非线性响应的活体动物三维融合成像设备，2021.01-2025.12，课题骨干
中国博士后科学基金，第1批特别资助（站前），2019TQ0018，近红外光学手术导航探针设计与应用，2019.07-2021.12，主持
研究领域
荧光分子探针研发及荧光手术导航临床应用研究
磁粒子成像技术应用研究
近期论文
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Li Changjian#, Jiahui Mi#, Yueqi Wang#, Zeyu Zhang, Xiaoyong Guo, Jian Zhou*, Zhenhua Hu*, Jie Tian*. New and effective EGFR-targeted fluorescence imaging technology for intraoperative rapid determination of lung cancer in freshly isolated tissue. European Journal of Nuclear Medicine and Molecular Imaging.2022. (Accept)
Yueqi Wang#, Li Changjian#, Jiaming Zhuo, Hui Hui1*, Bing Zhou*, Jie Tian*. The Detection of Divalent iron and Reactive Oxygen Species during Ferroptosis with the use of a Dual-Reaction Turn-On fluorescent probe. Molecular Imaging and Biology.2022. (Accept)
Qu Qiaojun, Zhang Zeyu, Guo Xiaoyong, Yang Junying, Cao Caiguang, Li Changjian, Zhang Hui*, Xu Pengfei*, Hu Zhenhua*, Tian Jie*. Novel multifunctional NIR-II aggregation-induced emission nanoparticles-assisted intraoperative identification and elimination of residual tumor. Journal of Nanobiotechnology, 2022, 20(1): 143.
Feng Xin, Li Yuhao, Zhang Shiyuan, Li Changjian, Tian Jie*. Quantitative hypoxia mapping using a self-calibrated activatable nanoprobe. Journal of Nanobiotechnology, 2022, 20.1: 1-15.
Zhang Xiaoning, Li Changjian, Zhang Zeyu, Hu Zhenhua, Tian Jie, Residual learning network for accurate and stable reconstruction in Cerenkov luminescence tomography, Medical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging, SPIE.
Li Changjian, Wang Yueqi, Huang Saipeng, Zhang Xiaojie, Kang Xiaoxuan, Sun Yanchi, Hu Ziyuan, Han Lu, Du Libo*, Liu Yang*. A photostable fluorescent probe for long-time imagining of lysosome in cell and nematode. Talanta. 2018; 188: 316-24.
Li Changjian, Wang Yueqi, Zhang Xiaojie, Guo Xueling, Kang Xiaoxuan, Du Libo*, Liu Yang*. Red fluorescent carbon dots with phenylboronic acid tags for quick detection of Fe(III) in PC12 cells. Journal of Colloid and Interface Science. 2018; 526:487-96.
Wang Yueqi#, Li Changjian#, Zhang Xiaojie, Kang Xiaoxuan, Li Yaru, Zhang Wenyu, Chen Yan, Liu Yang, Wang Weigang*, Ge Maofa, Du Libo*. Exposure to PM2.5 aggravates Parkinson’s disease via inhibition of autophagy and mitophagy pathway. Toxicology. 2021; 456:152770.
Wang Yueqi#, Li Changjian#, Du Libo*, Liu Yang*. A reactive oxygen species-responsive dendrimer with low cytotoxicity for efficient and targeted gene delivery. Chinese Chemical Letters. 2020; 31(1):275-80.
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