Anthony, Daniel C - University of Oxford - Department of Pharmacology

个人简介

Dr Daniel Anthony joined the Department in 2004 from Southampton (1998-2004) and runs the Experimental Neuropathology Laboratory.

研究领域

The focus of the work of our laboratory is research to identify how inflammation contributes to the outcome of acute and chronic brain injury or infection. There is now considerable evidence to support the idea that inflammation contributes, in a deleterious manner, not only to the archetypal inflammatory disease of the brain, multiple sclerosis, but also to acute neurological diseases, such as stroke and head trauma, and to chronic neurodegenerative diseases, such as Alzheimer's disease, prion disease, and HIV-related dementia.

近期论文

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Dickens, AM, Larkin, JR, Griffin, JL, Cavey, A, Matthews, L, Turner, MR, Wilcock, GK, Davis, BG, Claridge, TDW, Palace, J, Anthony, DC, and Sibson, NR (2014) A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis. Gunnoo, SB, Finney, HM, Baker, TS, Lawson, AD, Anthony, DC, and Davis, BG (2014) Creation of a gated antibody as a conditionally functional synthetic protein. Connell, JJ, Chatain, G, Cornelissen, B, Vallis, KA, Hamilton, A, Seymour, L, Anthony, DC, and Sibson, NR (2013) Selective permeabilization of the blood-brain barrier at sites of metastasis. Mardiguian, S, Serres, S, Ladds, E, Campbell, SJ, Wilainam, P, McFadyen, C, McAteer, M, Choudhury, RP, Smith, P, Saunders, F, Watt, G, Sibson, NR, and Anthony, DC (2013) Anti-IL-17A treatment reduces clinical score and VCAM-1 expression detected by in vivo magnetic resonance imaging in chronic relapsing EAE ABH mice. Jagannath, A, Butler, R, Godinho, SIH, Couch, Y, Brown, LA, Vasudevan, SR, Flanagan, KC, Anthony, D, Churchill, GC, Wood, MJA, Steiner, G, Ebeling, M, Hossbach, M, Wettstein, JG, Duffield, GE, Gatti, S, Hankins, MW, Foster, RG, and Peirson, SN (2013) The CRTC1-SIK1 pathway regulates entrainment of the circadian clock. Couch, Y, Martin, CJ, Howarth, C, Raley, J, Khrapitchev, AA, Stratford, M, Sharp, T, Sibson, NR, and Anthony, DC (2013) Systemic inflammation alters central 5-HT function as determined by pharmacological MRI.