王小虎 - 清华大学

个人简介

王小虎副研究员于2007年获得美国贝勒医学院分子病毒与微生物学博士学位，之后在贝勒医学院和美国德州MD安德森癌症中心进行博士后研究，2014年全职加入清华大学董晨院士团队，现为清华大学医学院副研究员。学术荣誉与奖励 2010-2013 美国多发性硬化症协会(NMS)博士后基金 fellowship

研究领域

王小虎副研究员长期从事Th17细胞领域相关的基础和应用研究

近期论文

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Chang D, Xing Q, Su Y, Zhao X, Xu W,Wang X*, Dong C*. (2020). The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation.Immunity.53(3):614-626.e4.(*共通迅论文) Wang X# *, Ni L#, Wan S, Zhao X, Ding X, Dejean A, Dong C*.(2020).Febrile temperature critically controls the differentiation and pathogenicity of T helper 17 cells.Immunity,52(2):328-341（共一作兼共通迅论文） Xu T#, Stewart KM#,Wang X#, Liu K, Xie M, Kyu JK, Li K, Ma T, Wang H, Ni L, Zhu S, Cao N, Zhu D, Zhang Y, Akassoglou K, Dong C, Driggers EM, Ding S. (2017). Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.Nature. 548(7666):228-233.（共一作论文） Wang X*, Ni L, Chang D, Lu H, Jiang Y, Kim BS, Wang A, Liu X, Zhong B, Yang X, Dong C*. (2017). Cyclic AMP-Responsive Element-Binding Protein (CREB) is Critical in Autoimmunity by Promoting Th17 but Inhibiting Treg Cell Differentiation.EBioMedicine.25:165-174.(一作兼共通讯) Wang Xand Dong C. (2013). The CD70-CD27 axis, a new brake in the T helper 17 cell response.Immunity. 38, 1-3. Wang X, Zhang Y, Yang XO, Nurieva RI, Chang SH, Ojeda SS, Kang HS, Schluns KS, Gui J, Jetten AM and Dong C. (2012). Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2.Immunity,36(1):23-31. Xu T#,Wang X#, Zhong B, Nurieva RI, Ding S, Dong C. (2011). Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein.J Biol Chem. 286(26):22707-10.(共一作论文) Wang X, Gao H, Shen Y, Weinstock G, Zhou J, and Palzkill T. (2008). A high-throughput percentage-of-binding strategy to measure binding energies in DNA-protein interactions: application to genome scale site discovery. Nucleic Acids Res. 36, 4863-71