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个人简介

In 2011, I joined the School of Pharmacy and Biomedical Sciences at the University of Portsmouth. My research focuses on the molecular networks that control the simultaneous production of differentiating muscle cells and muscle stem cells. I have established novel collaborations to accompany the work on the mouse and chicken model with work on zebrafish and Xenopus, aimed at identifying the basic, vertebrate specific regulatory mechanisms for muscle and muscle stem cell formation. Moreover, I have established collaborations to join “wet” laboratory work with “dry” bioinformatics. Furthermore, I have established collaborations to investigate the assembly of functional organs, including the innervation of muscle and the contribution of multi-potent precursors to either head skeletal muscle or heart. All of these collaborations have led to or are being prepared for publications. My findings have made a significant contribution to the field of developmental biology and are well represented in text books such as the renowned Gilbert’s “Developmental Biology”; I am also regularly invited for seminars. In 1998, I established the King’s College seminar series "Development and Evolution”. In 2008, also at King’s, I founded a novel national conference for young researchers in the area of muscle developmental, cell and molecular biology. Moreover, I was peer-selected to organise the 2009 Keystone muscle meeting “Making muscle in the embryo and the adult” in New York. I am on the editorial board of the leading journals in my field, “Development” and “Developmental Biology”, and I am regularly invited by journals and research councils to peer-review publications and grant applications.

研究领域

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Tissue interactions and molecular networks that control how a multi-potent mesodermal precursor cell commits to a particular cell fate when a cell may differentiate how the balance between cell differentiation and maintenance of a precursor/stem cell pool is achieved how this cell recognises and reaches its target sites how cells from different sources and tissues assemble into a functional organ

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