Donaldson, Craig - Plymouth University - School of Biomedical and Healthcare Sciences

个人简介

Qualifications 2004 PGCert in Teaching and Learning in Higher Education. University of the West of England 2003 CSci: Chartered Scientist 2003 PhD, Faculty of Medicine and Dentistry, University of Bristol 1987 Certificate in Health Service Management from Institute of Health Service Managers. 1985 M.Sc. Biochemical Immunology from CNAA, North East London Polytechnic 1982 FIBMS: Fellow of the Institute of Biomedical Sciences - Immunology 1980 HND in Medical Laboratory Sciences. Bristol Polytechnic

研究领域

My research expertise encompasses several aspect of stem cell transplantation. My current research focuses on chemotherapeutic damage to the marrow microenvironment /mesenchymal stem cells. At the University of Bristol I worked as a Research Fellow on the Cord Blood Research Programme which was set up to investigate the feasibility of collecting cord blood donations to extend the pool of donors available to patients requiring a haemopoietic stem cell (HSC) transplant. I gained extensive experience in managing a research programme having set up the techniques and procedures for the Bristol Cord Blood Bank. Subsequent research into expanding HSC in culture, to increase the stem dose available for transplant, thereby enhancing engraftment, gave me extensive experience of cell culture techniques.

近期论文

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Andrews SW, Kabrah S, May JE, Donaldson C & Morse HR 2013 'Multiple myeloma: the bone marrow microenvironment and its relation to treatment' Br J Biomed Sci 70, (3) 110-120 Author Site May JE, Morse HR, Xu J & Donaldson C 2012 'Development of a novel, physiologically relevant cytotoxicity model: application to the study of chemotherapeutic damage to mesenchymal stromal cells' Toxicol Appl Pharmacol 263, (3) 374-389 Author Site , DOI Brincat P, Degaetano J & Donaldson C 2012 'Evaluation of a method allowing preservation of fresh lymph nodes for flow cytometric immunophenotyping' CYTOMETRY PART B-CLINICAL CYTOMETRY 82B, (4) 245-251 Author Site , DOI Kemp K, Morse R, Sanders K, Hows J & Donaldson C 2011 'Alkylating chemotherapeutic agents cyclophosphamide and melphalan cause functional injury to human bone marrow-derived mesenchymal stem cells' Ann Hematol 90, (7) 777-789 Author Site , DOI May JE, Morse R, Xu J, Avent ND, Cox C, Wexler SA & Donaldson C 2010 'An in vitro model of chemotherapeutic damage to mesenchymal stem cells' MUTAGENESIS 25, (6) 633-633 Author Site Kemp K, Morse R, Wexler S, Cox C, Mallam E, Hows J & Donaldson C 2010 'Chemotherapy-induced mesenchymal stem cell damage in patients with hematological malignancy' Ann Hematol 89, (7) 701-713 Author Site , DOI Rees B, Morse R, Robinson S, Hows J & Donaldson C 2009 'A preliminary study of human natural killer T-cell recovery post allogeneic stem cell transplantation' BONE MARROW TRANSPLANTATION 43, S368-S368 Author Site May JE, Xu J, Morse HR, Avent ND & Donaldson C 2009 'Toxicity testing: the search for an in vitro alternative to animal testing' Br J Biomed Sci 66, (3) 160-165 Author Site Kemp KC, Hows J & Donaldson C 2005 'Bone marrow-derived mesenchymal stem cells' Leuk Lymphoma 46, (11) 1531-1544 Author Site , DOI